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121.
The performance of an optimization tool is largely determined by the efficiency of the search algorithms used in the process as well as the proper handling of complex constraints. From the implementation point of view, an important part of task ensuring an efficient algorithm to work to its best capability is to handle the boundary constraints properly and effectively. As most studies in the literature have focused on the development of algorithms and performance evaluation and comparison of optimization algorithms, this crucial step has not been explored very well, and consequently only limited studies have been carried out in this field. This paper intends to propose a simple and yet efficient evolutionary scheme for handling boundary constraints. The simplicity of this approach means that the proposed scheme is very easy to implement and thus can be suitable for many applications. We demonstrate this approach with an efficient algorithm, differential evolution, and we also compare it with other boundary constraint handling approaches for a wide set of benchmark problems. Based on statistical parameters and especially mean values, the results obtained by the evolutionary scheme are better than the best known solutions obtained by the existing methods.  相似文献   
122.
Because failures in lead-free solder joints occur at locations other than the most highly shear-strained regions, reliability prediction is challenging. To gain physical understanding of this phenomenon, physically based understanding of how elastic and plastic deformation anisotropy affect microstructural evolution during thermomechanical cycling is necessary. Upon solidification, SAC305 (Sn-3.0Ag-0.5Cu) solder joints are usually single or tricrystals. The evolution of microstructures and properties is characterized statistically using optical and orientation imaging microscopy. In situ synchrotron x-ray measurements during thermal cycling are used to examine how crystal orientation and thermal cycling history change strain history. Extensive characterization of a low-stress plastic ball grid array (PBGA) package design at different stages of cycling history is compared with preliminary experiments using higher-stress package designs. With time and thermal history, microstructural evolution occurs mostly from continuous recrystallization and particle coarsening that is unique to each joint, because of the specific interaction between local thermal and displacement boundary conditions and the strong anisotropic elastic, plastic, expansion, and diffusional properties of Sn crystals. The rate of development of recrystallized microstructures is a strong function of strain and aging. Cracks form at recrystallized (random) boundaries, and then percolate through recrystallized regions. Complications arising from electromigration and corrosion are also considered.  相似文献   
123.
124.
Construction of mechanically stabilized earth (MSE) walls in multi-tiered configurations is a promising solution for increasing the height of such walls. The good performance of this type of walls after recent major earthquakes was reported in a number of technical studies. In the present study, an experimental approach was adopted to compare the seismic performance of single-tiered and multi-tiered MSE walls using physical modeling and through conducting a series of uniaxial shaking table tests. To do so, several geogrid-reinforced soil walls with wrap-around facing (i.e., three-, two-, and single-tiered) with a total height of 10 m were designed in the form of prototypes of 1-m-height wall models. The step-wise intensified sinusoidal waves were applied to the models in 14 typical forms. Comparing the shaking table test results confirmed the post-earthquake advantages of multi-tiered MSE walls. The results revealed that tiered walls exhibited better behaviors under earthquake loading in terms of the seismic stability of the wall, displacement of the wall crest, horizontal displacement of the wall facing, deformation mode and failure mechanism of the wall, settlement of backfill surface, and seismic acceleration responses.  相似文献   
125.
Non-small cell lung cancer (NSCLC) patients with sensitizing mutations in the exons 18–21 of the epithelial growth factor receptor (EGFR) gene show increased kinase activity of EGFR. Hence, tyrosine kinase inhibitors (TKIs) such as erlotinib (ETB) have commonly been used as the second line therapeutic option for the treatment of metastatic NSCLC. While the ETB is available as an oral dosage form, the local delivery of this TKI to the diseased cells of the lung may ameliorate its therapeutic impacts. In the current study, we report on the development of ETB-loaded solid lipid nanoparticle (SLN) based formulation of dry powder inhaler (ETB-SLN DPI). ETB-SLNs were formulated using designated amount of compritol/poloxamer 407. The engineered ETB-SLNs showed sub-100?nm spherical shape with an encapsulation efficiency of 78.21%. MTT assay and DAPI staining revealed that the ETB-SLNs enhanced the cytotoxicity of cargo drug molecules in the human alveolar adenocarcinoma epithelial A549 cells as a model for NSCLC. To attain the ETB-SLN DPI, the ETB-SLNs were efficiently spray dried into microparticles (1–5?μm) along with mannitol. The ETB-SLN DPI powder displayed suitable flowability and aerodynamic traits. The Carr's Index, Hausner ratio and Next Generation Impactor (NGI) analyses confirmed deep inhalation pattern of the formulation. Based on these findings, we propose the ETB-SLN DPI as a promising treatment modality for the NSCLC patients.  相似文献   
126.
By the exponential increase in cellular communication area, the user demands and with their side problems also tend to increase. Several techniques such as cell splitting, frequency reuse, diversity and so on have already been applied to overcome these problems. In all these procedures, smart antenna is one of the best techniques used to boost capacities, enlarge bandwidth, raise the SIR ratios, minimize the effects of fading and improve MIMO communications. An ordinary antenna array which can turn up into a smart antenna array is due to the signal processing algorithms, which consists of angle of arrival (AOA) estimations and Beamforming. In this paper, I will discuss and analyse about the MUSIC algorithm for AOA estimation and least mean squares algorithm for Beamforming.  相似文献   
127.
Providing precise estimations of soil deformation modulus is very difficult due to its dependence on many factors. In this study, gene expression programming (GEP) and multi-expression programming (MEP) systems are presented to derive empirical equations for the prediction of the pressuremeter soil deformation modulus. The employed expression programming (EP) systems formulate the soil deformation modulus in terms of the soil physical properties. Selection of the best models is on the basis of developing and controlling several models with different combinations of the affecting parameters. The proposed EP-based models are established upon 114 pressuremeter tests on different soil types conducted in this study. The generalization capabilities of the models are verified using several statistical criteria. Contributions of the variables influencing the soil modulus are evaluated through a sensitivity analysis. The GEP and MEP approaches accurately characterize the soil deformation modulus resulting in a very good prediction performance. The result indicates that moisture content and soil dry unit weight can efficiently represent the initial state and consolidation history of soil for determining its modulus.  相似文献   
128.
In this communication, the kinetic parameters of methane hydrate formation (induction time, quantity and rate of gas uptake, storage capacity (SC), and apparent rate constant) in the presence of sodium dodecyl sulfate (SDS), synthetized silver nanoparticles (SNPs), and mixture of SDS?+?SNPs have been studied. Experimental measurements were performed at temperature of 273.65?K and initial pressure of 7?MPa in a 460?cm3 stirred batch reactor. Our results show that adding SDS, SNPs and their mixture increases the quantity of gas uptake, water to hydrate conversion, and SC of methane hydrate formation, noticeably. Using 300?ppm SDS increases the SC and the quantity of methane uptake 615, and 770%, respectively, compared with pure water. Investigating the hydrate growth rate at the start of hydrate formation process shows that, using SNPs, SDS, and their mixture increases the initial apparent rate constant of hydrate rate, considerably. Our results show that the system of methane?+?water?+?SDS 500?ppm?+?SNPs 45?µM represents the maximum value of initial apparent rate constant, compared with other tested systems.  相似文献   
129.
Vanadium pentoxide nanoparticles were synthesized using a solvo-thermal method and were characterized via X-ray powder diffraction (XRD) and field emission scanning electron microscopy (FE-SEM). The ozonation of palm oil was performed by using vanadium pentoxide nanoparticles as catalysts to synthesize ethyl malonate. This procedure presented several advantages, such as simple operation for a precise ozonation, excellent yield, short reaction times and reusability because of the recyclability of palm oil. Ethyl malonate was synthesized via the one-step ozonolysis of palm oil and was spectroscopically characterized using gas chromatography-mass spectroscopy (GC-MS).  相似文献   
130.
This paper describes two novel algorithms based on the time-modulo reconstruction method intended for detection of the parametric faults in analogue-to-digital converters (ADC). In both algorithms, a pulse signal, in its slightly adapted form to allow sufficient time for converter settling, is taken as the test stimulus relieving the burden placed on the accuracy requirement of the excitation source. Instead of calculating the accurate conventional dynamic and static parameters, a signature result is obtained through the analysis of the output data in the time domain. The basic concept of the algorithms is the evaluation on the performance of ADCs by the comparison of the similarity of the output waveforms. The multi-site test is expensive for traditional specification-based tests of ADCs, as high quality analogue data generators are required. Based on these two algorithms, this paper proposes a solution for this problem. The objective of the test scheme is not to completely replace traditional specification-based tests, but to provide a reliable method for early identification of excessive parameter variations in production test that allows quickly discarding of most of the faulty circuits before performing a conventional test. The efficiency of the methods is validated on an industrial 12-bit pipelined ADC both in simulations and in measurements.  相似文献   
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