Passive Filtration of Airborne Particles from Buildings Ventilated by Natural Convection: Design Procedures and a Case Study at the Buddhist Cave Temples at Yungang,China

Air exchange between interior spaces and the outdoor atmosphere can occur due to a variety of processes, including wind-driven flows and natural convectiondriven flows. As air is exchanged with the outdoors, airborne particles can be brought inside. Depending on the use of the indoor space, the presence of particles in indoor air could be a nuisance to the occupants or could be damaging to materials kept indoors. While one obvious solution to such problems is to install a mechanical air filtration system, that is not always practical. In particular, the character of some historical houses and some archaeological sites would be degraded by the presence of a mechanical air distribution system, and in some parts of the world the reliable electrical power supply needed for such a filtration system may not be available. In the present paper we consider principles for the design of passive filtration systems in which air motion through the filter material is induced by a natural convection flow rather than by a mechanical fan. A fluid mechanical model first is described for predicting the air flow through an interior space that acts as a thermal siphon. The effect of placing filter material in the path of such air flows is examined next. The indoor-outdoor air quality model of Nazaroff and Cass (1989a) is matched to the natural convection air exchange model, and calculations are performed to determine the relationship between the outdoor particle size distribution and indoor particle size distributions and particle deposition rates given a passive filtration system. Example calculations are worked for the case of a passive particle filtration system that could be installed to protect the interior of the Buddhist cave temples at Yungang, China. These are a collection of manmade cave temples dating from the 5th century AD, now situated in the middle of one of China's largest coal-mining regions with its accompanying air pollution problems.     

Levels of polybrominated diphenyl ether (PBDE) flame retardants in animals representing different trophic levels of the North Sea food Web

The levels of individual PBDE congeners were investigated in the invertebrate species whelk (Buccinum undatum), seastar (Asterias rubens), and hermit crab (Pagurus bernhardus), the gadoid fish species whiting (Merlangius merlangus) and cod (Gadus morhua), and the marine mammal species harbor seal (Phoca vitulina) and harbor porpoise (Phocoena phocoena). These species are all important representatives of different trophic levels of the North Sea food web. All six major PBDE congeners detected (BDEs 28, 47, 99, 100, 153, and 154) are most prevalent in the commercial Penta-BDE formulation. There is no evidence for the occurrence of the Octa-BDE formulation in the North Sea food web, since its dominant congener, BDE183, was never detected. BDE209, the main congener (> 97%) in the Deca-BDE formulation, was detected only in a minority of the samples and always in concentrations around the limit of detection. Since BDE209 is often the major BDE congener in sediments from the area, the main reason for its low concentrations in biota from the North Sea seems to be a relatively low bioaccumulation potential. This can either be due to a low uptake rate of the very large molecule or a relatively rapid excretion after biotransformation. Since all invertebrates investigated are sentinel species, they are highly representative for the area of capture. The highest lipid-normalized concentrations of PBDEs in the invertebrates occurred near the mouth of the river Tees at the East coast of the UK. The geographical distribution of the PBDEs can be explained by the residual currents in the area. The direction of these currents differs between the summer and the winter season as a result of the presence or absence of vertical summer stratification of the deeper waters north of the Dogger Bank. Summer stratification results in the development of a density-driven bottom water current formed after the onset of vertical stratification of the water column in May leaving the UK coast near Flamborough Head toward the Dogger Bank. In winter, the residual currents run in a more southerly direction and follow the UK coastline. The distribution pattern of the PCBs and p,p'-DDE in the invertebrates was entirely different from that of the PBDEs, which could be expected, since the use of these organochlorines in western Europe peaked in the 1960s and 1970s but has been forbidden more than two decades ago, whereas the production and use of the penta-BDE formulation is of a more recent origin. The higher trophic levels of the North Sea food web were represented by the predatory gadoid fish species whiting and cod and the marine mammal species harbor seal and harbor porpoise. The lipid-normalized levels of the six major PBDE congeners in fish were similar to the levels in the invertebrates, but a biomagnification step in concentrations of generally more than an order of magnitude occurred from gadoid fish to marine mammals. Based on the limited number of samples, no differences could be observed between harbor seal and harbor porpoise. In summary, the results in three species of sentinel invertebrates from a network of stations covering a major part of the North Sea basin showed that the estuary of the river Tees at the UK East coast is a major source for tri- to hexa-PBDEs. Throughout the food-chain, the most marked increase in (lipid-normalized) levels of all six PBDE congeners occurred from predatory (gadoid) fish to marine mammals, agreeing with the transition from gill-breathing to lung-breathing animals. This has serious consequences for the route of elimination of POPs, since their elimination from the blood into the ambient seawater via the gill-membrane is no longer possible.     

Reliable 3-phase PWM boost rectifiers employing a stacked dualboost converter subtopology

This paper describes circuit topologies for three-phase pulse-width modulation (PWM) boost rectifiers that operate with a unity fundamental power factor and a low-distortion AC line current. Overlap delays between the switching of the upper and lower devices in a PWM rectifier leg are not critical and diodes eliminate the possibility of the DC-link capacitor discharging into short circuits and shoot-through fault conditions. The rectifiers are controlled using a “stacked dual boost converter cell” subtopology model that can be used in two current control modes. The dual current-control mode shapes two line currents and can achieve current distortion levels below 5%. The single current control mode shapes one line current and can achieve current distortion levels close to 5% with the rectifier output DC voltage at the standard level associated with a rectified mains voltage. The per-unit current ratings for the switches in the three-phase PWM switch networks are around 15-20% of the input RMS line current as compared to 71% for a standard three-phase PWM rectifiers. Circuit simulations and experimental results are used to demonstrate the performance and feasibility of the rectifiers described     

Algorithm analysis of lectin glycohistochemistry and Feulgen cytometry for a new classification of nasal polyposis

The aim of this study is to present a new classification of nasal polyps. This classification is based both on morphologic criteria relating to morphonuclear features from isolated Feulgen-stained nuclei and on glycohistochemical characteristics from histologic slides submitted to three lectins (peanut, wheat germ, and gorse seed agglutinins) and one neoglycoconjugate glycohistochemical stain. While the morphonuclear features (including 30 variables) relate essentially to chromatin pattern, the glycohistochemical stains (including 16 variables) are linked to the presence of specific carbohydrate moieties in cell membranes and cytoplasm. Forty-nine nasal polyps, including single polyps, diffuse polyposis, cystic fibrosis-related polyposis, and aspirin idiosyncracy-related polyposis associated with asthma, were thus characterized. All the variables were obtained quantitatively by means of computer-assisted microscopy. Two complementary methods of data classification were used to determine the actual diagnostic value contributed by each quantitative variable, namely, discriminant analysis, which forms part of multifactorial statistical analysis, and the decision tree technique, which is an artificial intelligence-related algorithm. The data so obtained show that our morphologic classification of nasal polyps fits in with the classification of nasal polyps defined on the basis of clinical criteria.     

Event-related brain potentials during semantic categorization in normal aging and senile dementia of the Alzheimer's type

To assess the effects of normal aging and senile dementia of the Alzheimer's type (SDAT) on semantic analysis of words, we examined the N400 component of the event-related potential (ERP) elicited during the processing of highly constrained (opposites) and less constrained materials (category-category exemplars) in 12 young control subjects, 12 elderly control subjects and 12 patients with SDAT. We employed a priming paradigm in which a context phrase was spoken and a target word (congruent or incongruent) was presented visually. The N400 effect was reduced in amplitude and delayed in the elderly control group relative to that of the younger subjects, and was further attenuated in amplitude, delayed in latency and somewhat flatter in its distribution across the scalp in the SDAT patients. These findings are consistent with less efficient processing and integration of lexical items with semantic context in normal aging, which is further exacerbated by SDAT. Differences in the N400 range associated with the opposite and category conditions were observed only in the young subjects, suggesting less use of controlled attentional resources or perhaps weaker associative links with age.     

Processing and retention of complex auditory stimuli in monkeys (Cebus apella).

Four monkeys were trained to discriminate between "tunes" that differed primarily in their temporal structure, or frequency envelopes. The conclusion drawn from a variety of transfer tests was that they learned the discrimination on the basis of local features of the tunes rather than on their temporal patterns. Subsequent comparisons of retention based on auditory–visual and visual–visual matching tasks suggested that this deficiency was not due to a truncated auditory short-term store. Indeed, when previous experience with remembering visual and auditory stimuli was comparable, short-term memory also seemed comparable in the 2 modalities. It is noted that the ability to discriminate and employ the frequency contours of tonal patterns may be related to the capacity for acoustically based language, and that in the human infant, these skills seem to develop in parallel. (French abstract) (36 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

A naturally occurring mutation in Fc gamma RIIA: a Q to K127 change confers unique IgG binding properties to the R131 allelic form of the receptor

Fc gamma RIIa is widely expressed on hematopoietic cells. There are two known allelic polymorphic forms of Fc gamma RIIa, Fc gamma RIIa-R131 and Fc gamma RIIa-H131, which differ in the amino acid at position 131 in the second lg-like domain. In contrast to Fc gamma RIIa-R131, Fc gamma RIIa-H131 binds hlgG2 but not mIgG1, and this differential binding has clinical implications for host defense, autoimmune disease, immunohematologic disease, and response to therapeutic monoclonal antibodies. We identified a novel Fc gamma RIIA genotype in a healthy individual homozygous for Fc gamma RIIA R/R131 in whom a C to A substitution at codon 127 changes glutamine (Q) to lysine (K) in one of the two Fc gamma RIIA genes. This individual's homozygosity for Fc gamma RIIA-R/R131 leads to the prediction that the receptors on her cells would not bind hIgG2. Monocyte and neutrophil phagocytosis of hIgG2-opsonized erythrocytes was significantly higher (P < .05) for cells from this K/Q127, R/R131 individual than for Q/Q127, R/R131 donors. Platelet aggregation stimulated by an mIgG1 anti-CD9 antibody in this individual was significantly different (P < .05) from Q/Q127, H/R131 and Q/Q127, H/H131 donors and similar to Q/Q127, R/R131. Our data show that the K127/R131 receptors have a unique phenotype, binding both hIgG2 and mIgG1. Further functionally significant mutations in human Fc gamma receptors and possible novel mechanisms for inherited differences in disease susceptibility should be sought with unbiased screening methods.     

Design of linear feedback controllers for nonlinear plants

Two related methods are developed for designing linear feedback controllers for nonlinear plants with initial states that are unknown but restricted to a given domain. It is shown that the well-known neighboring optimum method of controller design can be considered as a special case of the methods proposed here.