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81.
W.M. Charles E. van den BergAuthor Vitae H.X. LinAuthor VitaeA.W. HeeminkAuthor Vitae M. Verlaan 《Journal of Parallel and Distributed Computing》2008
This paper describes the parallel simulation of sediment dynamics in shallow water. By using a Lagrangian model, the problem is transformed to one in which a large number of independent particles must be tracked. This results in a technique that can be parallelised with high efficiency. We have developed a sediment transport model using three different sediment suspension methods. The first method uses a modified mean for the Poisson distribution function to determine the expected number of the suspended particles in each particular grid cell of the domain over all available processors. The second method determines the number of particles to suspend with the aid of the Poisson distribution function only in those grid cells which are assigned to that processor. The third method is based on the technique of using a synchronised pseudo-random-number generator to generate identical numbers of suspended particles in all valid grid cells for each processor. Parallel simulation experiments are performed in order to investigate the efficiency of these three methods. Also the parallel performance of the implementations is analysed. We conclude that the second method is the best method on distributed computing systems (e.g., a Beowulf cluster), whereas the third maintains the best load distribution. 相似文献
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Alireza Kargar Supanee Sukrittanon Chang Zhou Yun Goo Ro Xiaoqing Pan Shadi A. Dayeh Charles W. Tu Sungho Jin 《Small (Weinheim an der Bergstrasse, Germany)》2017,13(21)
The growth and characterization of an n‐GaP/i‐GaNP/p+‐GaP thin film heterojunction synthesized using a gas‐source molecular beam epitaxy (MBE) method, and its application for efficient solar‐driven water oxidation is reported. The TiO2/Ni passivated n‐GaP/i‐GaNP/p+‐GaP thin film heterojunction provides much higher photoanodic performance in 1 m KOH solution than the TiO2/Ni‐coated n‐GaP substrate, leading to much lower onset potential and much higher photocurrent. There is a significant photoanodic potential shift of 764 mV at a photocurrent of 0.34 mA cm?2, leading to an onset potential of ≈0.4 V versus reversible hydrogen electrode (RHE) at 0.34 mA cm?2 for the heterojunction. The photocurrent at the water oxidation potential (1.23 V vs RHE) is 1.46 and 7.26 mA cm?2 for the coated n‐GaP and n‐GaP/i‐GaNP/p+‐GaP photoanodes, respectively. The passivated heterojunction offers a maximum applied bias photon‐to‐current efficiency (ABPE) of 1.9% while the ABPE of the coated n‐GaP sample is almost zero. Furthermore, the coated n‐GaP/i‐GaNP/p+‐GaP heterojunction photoanode provides a broad absorption spectrum up to ≈620 nm with incident photon‐to‐current efficiencies (IPCEs) of over 40% from ≈400 to ≈560 nm. The high low‐bias performance and broad absorption of the wide‐bandgap GaP/GaNP heterojunctions render them as a promising photoanode material for tandem photoelectrochemical (PEC) cells to carry out overall solar water splitting. 相似文献
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Chinazom Agbo Franklin Kenechukwu John Ogbonna Salome Chime Charles Lovelyn 《Drug development and industrial pharmacy》2016,42(10):1708-1721
Context: Poor aqueous solubility of artemether and lumefantrine makes it important to seek better ways of enhancing their oral delivery and bioavailability.Objective: To formulate and carry out in vitro and anti-malarial pharmacodynamic evaluations of solidified reverse micellar solutions (SRMS)-based solid lipid microparticles (SLMs) of artemether and lumefantrine for oral delivery and improved bioavailability.Materials and methods: Rational blends of Softisan®154 and Phospholipon®90H lipid matrices, and different concentrations of artemether and lumefantrine were used to formulate several batches of SLMs. Drug-free SLMs were also formulated. Morphology, particle size, encapsulation efficiency (EE%) and pH studies were performed. In vitro release studies were performed in alcoholic buffer, simulated gastric fluid (SGF) and simulated intestinal fluid (SIF) without enzymes. Anti-malarial pharmacodynamic studies were conducted in mice.Results: Stable, smooth and spherical particles with sizes ranging from 4.2?±?0.02 to 9.3?±?0.8?µm were formed. EE% of 92.2–97.3% and 30.2–84.7% and pH of 3.0?±?0.02 to 4.9?±?0.12 and 3.0?±?0.02 to 5.8?±?0.05 were obtained for artemether and lumefantrine SLMs, respectively. Release of 100, 88.28 and 75.49%, as well as 63.26, 34.31 and 56.17% were recorded for artemether and lumefantrine in alcoholic buffer, SGF and SIF, respectively. Pharmacodynamic studies indicated very significant (p?0.05) clearance of parasitaemia in plasmodium-infected mice by the drug-loaded SLMs.Conclusion: Oral delivery and bioavailability of artemether and lumefantrine could be improved using SRMS-based SLMs. 相似文献
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Dorsa Parviz Fahmida Irin Smit A. Shah Sriya Das Charles B. Sweeney Micah J. Green 《Advanced materials (Deerfield Beach, Fla.)》2016,28(40):8796-8818
Recent developments in the exfoliation, dispersion, and processing of pristine graphene (i.e., non‐oxidized graphene) are described. General metrics are outlined that can be used to assess the quality and processability of various “graphene” products, as well as metrics that determine the potential for industrial scale‐up. The pristine graphene production process is categorized from a chemical engineering point of view with three key steps: i) pretreatment, ii) exfoliation, and iii) separation. How pristine graphene colloidal stability is distinct from the exfoliation step and is dependent upon graphene interactions with solvents and dispersants are extensively reviewed. Finally, the challenges and opportunities of using pristine graphene as nanofillers in polymer composites, as well as as building blocks for macrostructure assemblies are summarized in the context of large‐scale production. 相似文献
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Provides an overview of the 1995 Consumer Reports survey of the effectiveness of psychotherapy. Specific issues addressed include the study's goals; the findings for mental health professionals, family doctors, and self-help groups; and methodological strengths and weaknesses related to external validity, sampling, controls, self-reports, and time frame. The data show that, free of the artificial constraints of controlled studies in the real world, a population of consumers can often benefit from psychological intervention services. Real relief can be found at the hands of professional mental health providers. M. Kotkin et al reaffirm their independence from M. E. P. Seligman (see record 1996-13324-001) regarding the interpretation of the data. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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Borkin MA Gajos KZ Peters A Mitsouras D Melchionna S Rybicki FJ Feldman CL Pfister H 《IEEE transactions on visualization and computer graphics》2011,17(12):2479-2488
Heart disease is the number one killer in the United States, and finding indicators of the disease at an early stage is critical for treatment and prevention. In this paper we evaluate visualization techniques that enable the diagnosis of coronary artery disease. A key physical quantity of medical interest is endothelial shear stress (ESS). Low ESS has been associated with sites of lesion formation and rapid progression of disease in the coronary arteries. Having effective visualizations of a patient's ESS data is vital for the quick and thorough non-invasive evaluation by a cardiologist. We present a task taxonomy for hemodynamics based on a formative user study with domain experts. Based on the results of this study we developed HemoVis, an interactive visualization application for heart disease diagnosis that uses a novel 2D tree diagram representation of coronary artery trees. We present the results of a formal quantitative user study with domain experts that evaluates the effect of 2D versus 3D artery representations and of color maps on identifying regions of low ESS. We show statistically significant results demonstrating that our 2D visualizations are more accurate and efficient than 3D representations, and that a perceptually appropriate color map leads to fewer diagnostic mistakes than a rainbow color map. 相似文献
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