中药知母有效组分——知母皂甙元“滋阴”作用的研究

本工作以~(123)I-心得静结合分析法及环核苷酸RIA法观察了知母中提取得到的知母皂甙元对甲亢模型(模拟“阴虚”)βAR-cAMP系统的作和,结果表现,知母皂甙元明显降低甲亢小鼠脑β受体的RT值,显著降低甲亢小鼠β受体-cAMP系统的反应性,重现了知母水煎剂的下调作用。体外竞争抑制实验表明,知母皂甙元和知母皂甙元半琥珀酸都不能抑制~(125)I-心得静与β受体的结合。     

水利对粮食生产贡献率的认识与思考

针对目前很多人对农业科技进步贡献率和水利对粮食生产贡献率的不同认识,从发展历程、概念内涵、测算思路方法等方面,剖析了二者差异,认为二者在测算范围上存在大口径与小口径的差异,在测算对象上存在增量与总量的差异,在测算指标上存在产值与产量的差异,在测算方法上存在余值法与有无对比法的差异,为正确认识这两个指标提供了参考。     

Acoustic emission from gas-filled coal under triaxial compression

Acoustic emission (AE) experiments have been performed on gas-saturated coal specimens under conventional triaxial compression. The AE characteristics were investigated for a methane gas flow through the coal specimen. One AE parameter, AE count, when normalized by the total count number was used to represent the damage evolution in the gassy coal. It is shown that this AE parameter is a reasonable indicator for damage occurring within the coal specimen since its envelope has almost the same shape as the complete stress–strain curve, except for a short time delay. In addition, the change in AE count is highly consistent with the change in coal permeability. Test results also show that methane containing coal emits a small number of AE events before entering the yield stage. AE activity gradually increases during the yield process up to the peak stress. The lowest permeability corresponds to the highest AE activity, implying failure will soon occur. An AE based constitutive model was constructed and the theoretical results agree well with those of experiments.     

Robust and efficient ridge-based palmprint matching

During the past decade, many efforts have been made to use palmprints as a biometric modality. However, most of the existing palmprint recognition systems are based on encoding and matching creases, which are not as reliable as ridges. This affects the use of palmprints in large-scale person identification applications where the biometric modality needs to be distinctive as well as insensitive to changes in age and skin conditions. Recently, several ridge-based palmprint matching algorithms have been proposed to fill the gap. Major contributions of these systems include reliable orientation field estimation in the presence of creases and the use of multiple features in matching, while the matching algorithms adopted in these systems simply follow the matching algorithms for fingerprints. However, palmprints differ from fingerprints in several aspects: 1) Palmprints are much larger and thus contain a large number of minutiae, 2) palms are more deformable than fingertips, and 3) the quality and discrimination power of different regions in palmprints vary significantly. As a result, these matchers are unable to appropriately handle the distortion and noise, despite heavy computational cost. Motivated by the matching strategies of human palmprint experts, we developed a novel palmprint recognition system. The main contributions are as follows: 1) Statistics of major features in palmprints are quantitatively studied, 2) a segment-based matching and fusion algorithm is proposed to deal with the skin distortion and the varying discrimination power of different palmprint regions, and 3) to reduce the computational complexity, an orientation field-based registration algorithm is designed for registering the palmprints into the same coordinate system before matching and a cascade filter is built to reject the nonmated gallery palmprints in early stage. The proposed matcher is tested by matching 840 query palmprints against a gallery set of 13,736 palmprints. Experimental results show that the proposed matcher outperforms the existing matchers a lot both in matching accuracy and speed.     

Identification of Breast Cancer Prognosis Markers via Integrative Analysis

In breast cancer research, it is of great interest to identify genomic markers associated with prognosis. Multiple gene profiling studies have been conducted for such a purpose. Genomic markers identified from the analysis of single datasets often do not have satisfactory reproducibility. Among the multiple possible reasons, the most important one is the small sample sizes of individual studies. A cost-effective solution is to pool data from multiple comparable studies and conduct integrative analysis. In this study, we collect four breast cancer prognosis studies with gene expression measurements. We describe the relationship between prognosis and gene expressions using the accelerated failure time (AFT) models. We adopt a 2-norm group bridge penalization approach for marker identification. This integrative analysis approach can effectively identify markers with consistent effects across multiple datasets and naturally accommodate the heterogeneity among studies. Statistical and simulation studies demonstrate satisfactory performance of this approach. Breast cancer prognosis markers identified using this approach have sound biological implications and satisfactory prediction performance.     

自行车椭圆链轮传动机构的分析设计

分析了自行车的连续圆周运动不能使脚蹬力均匀变化的特性,对传统自行车的传动机构中存在的问题进行了改进。本文基于人机工程学原理用椭圆链轮代替主动圆链轮作为自行车的不等速传动装置,对该传动机构进行了优化,克服了自行车传动过程中出现的缺点,能最大限度的发挥人体结构的用力功能,从而推广了自行车的新应用。     

Monitoring the Synthesis and Composition Analysis of Microsilica Encapsulated Acetylacetonatocarbonyl TriphenylphosphinerhodiumCatalyst by Inductively Coupled Plasma (ICP) Techniques

A novel technique to monitor the synthesis process of encapsulated acetylacetonatocarbonyl triphenylphosphinerhodium within a microsilica nanoshell has been studied using inductively coupled plasma (ICP) techniques. Nanospheres sized around 50-100 nm were obtained and ICP was used to quantify the exact composition of rhodium, phosphorous, and silicon with differing digestion solvents. In addition, ICP was used to detect rhodium and phosphorous in the nano core-shell catalysts as a quality control procedure     

基于Intel 815E芯片组的PCI-104 CPU模块设计

本文描述了基于Intel815E芯片组的PCl-104 CPU模块设计,对系统结构、总线拓扑、系统存储器以及外设等在设计过程中的注意事项作了阐述.     

喷射沉积柱坯的生长模型

根据现有喷射沉积设备的喷射几何关系推导了柱状沉积坯生长的数学模型,并利用该模型对沉积器的临界下降速度进行了初步估算。     

高性能聚酰亚胺纤维

本文综述了聚酰亚胺纤维的性能及其制备工艺,以及聚酰亚胺纤维在结构方面的研究及纤维成型新技术、新工艺。