Background synaptic activity as a switch between dynamical states in a network

A bright red light may trigger a sudden motor action in a driver crossing an intersection: stepping at once on the brakes. The same red light, however, may be entirely inconsequential if it appears, say, inside a movie theater. Clearly, context determines whether a particular stimulus will trigger a motor response, but what is the neural correlate of this? How does the nervous system enable or disable whole networks so that they are responsive or not to a given sensory signal? Using theoretical models and computer simulations, I show that networks of neurons have a built-in capacity to switch between two types of dynamic state: one in which activity is low and approximately equal for all units, and another in which different activity distributions are possible and may even change dynamically. This property allows whole circuits to be turned on or off by weak, unstructured inputs. These results are illustrated using networks of integrate-and-fire neurons with diverse architectures. In agreement with the analytic calculations, a uniform background input may determine whether a random network has one or two stable firing levels; it may give rise to randomly alternating firing episodes in a circuit with reciprocal inhibition; and it may regulate the capacity of a center-surround circuit to produce either self-sustained activity or traveling waves. Thus, the functional properties of a network may be drastically modified by a simple, weak signal. This mechanism works as long as the network is able to exhibit stable firing states, or attractors.     

Specific interactions study in complexes of poly(mono-n-alkyl itaconates) with tertiary polyamides

This paper reports an FT-IR study of blends of poly(mono-n-alkyl itaconates) with poly(N,N-dimethylacrylamide) (PDMA) and poly(ethyloxazoline) (PEOX). Strong hydrogen bonding has been found, and both polybases have shown similar acceptor strengths. Derivative techniques show asymmetric profiles for the free carbonyl band of the polybases, resulting in shifted band locations. The extent of the interassociation has been estimated by spectral curve fitting of the polybase carbonyl band. The results show that the interaction degree in blends with PEOX does not depend on the length of the poly(monoalkyl itaconate) side group, while an inter-associating ability loss is observed in blends with PDMA as the side-group size of the polyacid increases. This different behavior is attributed to the greater interspacing between vicinal carbonyl groups in PEOX. This band shows conformational sensitivity and reflects the conformational changes that occur as the steric hindrances present in the medium (due to the bulky side groups of the polyacids) increase.     

Maximum and Minimum Likelihood Hebbian Learning for Exploratory Projection Pursuit

In this paper, we review an extension of the learning rules in a Principal Component Analysis network which has been derived to be optimal for a specific probability density function. We note that this probability density function is one of a family of pdfs and investigate the learning rules formed in order to be optimal for several members of this family. We show that, whereas we have previously (Lai et al., 2000; Fyfe and MacDonald, 2002) viewed the single member of the family as an extension of PCA, it is more appropriate to view the whole family of learning rules as methods of performing Exploratory Projection Pursuit. We illustrate this on both artificial and real data sets.     

Structural and physical properties of microwave synthesized orthorhombic perovskite erbium chromite ErCrO3

Rare-earth chromite ErCrO₃ powder was synthesized from metal nitrate precursors using microwave synthesis. (Micro-) structural characterizations were performed using X-ray diffraction, Rietveld refinement, High Resolution Transmission Electron Microscopy and Electron Micro-Diffraction. Magnetization vs. temperature measurements revealed anti-ferromagnetism with T_Neel ≈ 135 K. An anti-ferrimagnetic moment of ≈0.4 μ_B was determined from magnetization vs. applied field measurements. Temperature dependent impedance spectroscopy (IS) indicated 3 dielectric relaxation processes: electrode interface, grain boundary and bulk. The intrinsic bulk activation energy was found to be 0.27 eV and the dielectric permittivity ?_r was ≈23 in excellent agreement with Clausius-Mossotti predictions and showed no perceptible temperature dependence. This and the low ?_r value suggested that ErCrO₃ is a dielectric rather than ferroelectric compound. IS measurements with applied dc bias revealed the signs of an unconventional type of Schottky barrier at the metallic Au electrode/ceramic ErCrO₃ interface.     

Enzymatic production of human milk fat substitutes containing palmitic and docosahexaenoic acids at sn-2 position and oleic acid at sn-1,3 positions

This paper studies the synthesis of structured triacylglycerols (STAGs) rich in palmitic and docosahexaenoic acids (PA and DHA) at sn-2 position and oleic acid (OA) at sn-1,3 positions by a four step process. First, triacylglycerols (TAGs) were obtained with 63–66 mol PA/100 mol total fatty acids and 10 mol DHA/100 mol by acidolysis of tuna oil and commercial PA, catalyzed by the non-positionally specific lipase Novozym 435. Then these TAGs were purified neutralizing the free fatty acids (FFAs) by KOH hydroethanolic solutions and extracting TAGs with hexane; these TAGs were completely recovered as pure TAGs (without FFAs). The third step involved the displacement of fatty acids located at sn-1,3 positions by acidolysis of PA and DHA enriched TAGs with OA rich FFAs, catalyzed by the sn-1,3 specific lipase DF from Rhizopus oryzae, immobilized on Accurel MP-1000; TAGs with 67 mol OA/100 mol at sn-1,3 positions and 52.1 and 15.4 mol PA and DHA, respectively, per 100 mol at sn-2 position were obtained. Both acidolysis reactions were carried out in stirred tank reactors (STRs) with lipase both dispersed in the reaction medium and contained in a cartridge filter attached to the stirrer rod. Finally STAGs were purified and obtained with yields of over 80 mol STAGs/100 mol STAGs in the reaction product (no FFAs were detected).     

Smart Collaborative Mobile System for Taking Care of Disabled and Elderly People

Official statistics data show that in many countries the population is aging. In addition, there are several illnesses and disabilities that also affect a small sector of the population. In recent years, researchers and medical foundations are working in order to develop systems based on new technologies and enhance the quality of life of them. One of the cheapest ways is to take advantage of the features provided by the smartphones. Nowadays, the development of reduced size smartphones, but with high processing capacity, has increased dramatically. We can take profit of the sensors placed in smartphones in order to monitor disabled and elderly people. In this paper, we propose a smart collaborative system based on the sensors embedded in mobile devices, which permit us to monitor the status of a person based on what is happening in the environment, but comparing and taking decisions based on what is happening to its neighbors. The proposed protocol for the mobile ad hoc network and the smart system algorithm are described in detail. We provide some measurements showing the decisions taken for several common cases and we also show the performance of our proposal when there is a medium size group of disabled or elderly people. Our proposal can also be applied to take care of children in several situations.     

Needs and desires: transcending the ‘bipolar tendency’

The paper connects two of the concerns of this special issue: the way to transcend the ‘bipolar tendency’ of the market culture and to ‘deal with the swings between prophesies of doom that serve only to paralyse us further, and the unbridled consumerism that makes things worse’, and how to remain human when being mediated by technology in contrast to how we are in the presence of others. Our contribution is based on an extensive conception of human beings (HBs). HBs cannot be considered only as cognitive subjects but also in their anthropological integrity. What we mean by this that they think and feel, they share concepts and emotions, they plan and desire. It implies that any attempt at reducing this complexity is a way to diminish human beings and their capabilities. HBs need meaningful course of actions to manage complexity and to tackle alternatives. Meanings come from purposeful activities, and people’s purposes are based not only on utilitarian or rational enquiries but also on what they consider right and good, according to their vision of the world. This is also the key to overcome the ‘bipolar tendency’.     

Asset Price Anomalies under Bounded Rationality

We analyze the classical asset pricing model assuming non fully rationalagents.Agents forecast future prices cum dividend through an adaptive learning rule.This assumption provides an explanation of some anomalies encounteredin the empirical analysis of asset prices under full rationality:returns are serially correlated(positively over a short horizon and negatively over a longer horizon)and the dividend yield predicts future returns (positive correlation).Considering the continuous time limit process,the same regularities are established analytically for price increments.