No, It Is Not Possible to Be Schizophrenic Yet Neuropsychologically Normal.

Cognitive impairment is well documented in schizophrenia, though some reports have been interpreted to suggest that it is possible to have schizophrenia without neuropsychological impairment. The authors tested this by comparing the neuropsychological profiles of closely matched patients with schizophrenia and healthy comparison participants. Sixty-four patients with schizophrenia and 64 healthy comparison cases, matched to within 3 Full-Scale IQ points, were tested using the Wechsler Adult Intelligence Scale (3rd ed.; D. Wechsler, 1997b) and the Wechsler Memory Scale (3rd ed.; D. Wechsler, 1997c). Neuropsychological profiles for these groups were markedly different, with the group of patients with schizophrenia exhibiting performance deficits in memory and speeded visual processing but superior verbal comprehension and perceptual organization relative to the group of healthy comparison participants matched on Full-Scale IQ. Thus, scoring in the normal range does not preclude neuropsychological abnormality in schizophrenia, confirming that neuropsychological impairment is a core feature of the illness. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Innovative hydrogen release from sodium borohydride hydrolysis using biocatalyst-like Fe2O3 nanoparticles impregnated on Bacillus simplex bacteria

For the first time in this innovative study, microorganisms such as Bacillus simplex bacteria, mostly used in biological activity studies, are used as a bio-supporter agent of iron to release hydrogen from sodium borohydride hydrolysis at 25.0 ± 0.1 °C. The goal is to investigate thoroughly sodium borohydride hydrolysis catalyzed by Fe₂O₃ nanoparticles impregnated on microorganism such as Bacillus simplex (BS) bacteria (Fe₂O₃@BS NPs) known with strong antibacterial properties, which makes innovative them a candidate for hydrolysis reaction. This study was focused on the preparation, identification, and catalytic use of biocatalyst-like Fe₂O₃@BS NPs for hydrogen release from the sodium borohydride hydrolysis at 25.0 ± 0.1 °C. The characterization results made after and before hydrolysis reaction using by SEM/SEM-EDX, FT-IR, XRD, UV–vis, XPS, DLS, ELS Zeta potential, ESR, and TEM techniques reveal the formation of highly active, stable, durable, and long-lived biocatalysts-like Fe₂O₃@BS NPs.     

Restoring coverage to the Bayesian false discovery rate control procedure

Principal among knowledge discovery tasks is recognition of insightful patterns or features from data that can inform otherwise challenging decisions. For the costly future decisions, there is little room for error. Features must provide substantial evidence to be robust for classification and dependable for important decisions. Here we seek statistical evidence for feature selection, that feature signals are of sufficient magnitude and frequency to be generalizable for classification. The Bayesian false discovery rate (bFDR) error control procedure is powerfully suited for this task. In realistic situations often encountered in practice, the bFDR procedure is biased, yielding a greater than desired FDR. In other less typical cases, the FDR is less than desired. We investigate the sources of bias in the bFDR procedure, and predict the direction of bias. A new algorithm has been developed to recover the bias in the bFDR control procedure. In simulation and real data mining examples, the new bFDR control algorithm shows promise. The strengths and limitations of the new approach are presented with examples and discussed.     

Linear nearest neighbor optimization in quantum circuits: a multiobjective perspective

Several current implementations of quantum circuits rely on the linear nearest neighbor restriction, which only allows interaction between adjacent qubits. Most methods that address the process of converting a generic circuit to an equivalent circuit which satisfies this restriction, minimize the number of additional SWAP gates required by this process. Moreover, most methods which address this problem are designed for 1D circuits. Considering the new and promising proposals for 2D quantum circuits, what we propose is a new perspective on this problem, namely that it can be seen as a multiobjective optimization problem. To test our hypothesis, we developed a multiobjective evolutionary algorithm that solves this problem by considering two objectives: minimizing the size of the 2D grid where the circuit is placed, and minimizing the number of additional SWAP gates. Of the methods designed for 2D circuits, only one considers different grid sizes which are much larger than strictly necessary. Consequently, our algorithm makes considerations which other methods do not make, since it naturally finds the grid which requires fewer SWAP gates for the circuit conversion, whether it is one-dimensional or two-dimensional. Our experimental results indicate that allowing a larger grid size results in fewer additional SWAP gates in about 73% of the tested circuits. Additionally, the average improvement we found when using larger grid sizes is about 30%, while the best improvement over using the smallest possible grid is 63.8%.     

Effect of Vertical Misfit on Screw Joint Stability of Implant-Supported Crowns

The passive fit between prosthesis and implant is a relevant factor for screw joint stability and treatment success. The aim of this study was to evaluate the influence of vertical misfit in abutment-implant interface on preload maintenance of retention screw of implant-supported crowns. The crowns were fabricated with different abutments and veneering materials and divided into 5 groups (n = 12): Gold UCLA abutments cast in gold alloy veneered with ceramic (Group I) and resin (Group II), UCLA abutments cast in titanium veneered with ceramic (Group III) and resin (Group IV), and zirconia abutments with ceramic veneering (Group V). The crowns were attached to implants by gold retention screws with 35-N cm insertion torque. Specimens were submitted to mechanical cycling up to 10⁶ cycles. Measurements of detorque and vertical misfit in abutment-implant interface were performed before and after mechanical cycling. ANOVA revealed statistically significant difference (P < 0.05) among groups for vertical misfit measured before and after mechanical cycling. The abutments cast in titanium exhibited the highest misfit values. Pearson correlation test did not demonstrate significant correlation (P > 0.05) between vertical misfit and detorque value. It was concluded that vertical misfit did not influence torque maintenance and the abutments cast in titanium exhibited the highest misfit values.