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71.
Alireza Shamsi Amir Shamloo Negar Mohammadaliha Hassan Hajghassem Jalil Fallah Mehrabadi Masoumeh Bazzaz 《Microsystem Technologies》2016,22(10):2447-2454
Since plasma is rich in many biomarkers used in clinical diagnostic experiments, microscale blood plasma separation is a primitive step in most of microfluidic analytical chips. In this paper, a passive microfluidic device for on-chip blood plasma separation based on Zweifach–Fung effect and plasma skimming was designed and fabricated by hot embossing of microchannels on a PMMA substrate and thermal bonding process. Human blood was diluted in various times and injected into the device. The main novelty of the proposed microfluidic device is the design of diffuser-shaped daughter channels. Our results demonstrated that this design exerted a considerable positive influence on the separation efficiency of the passive separator device, and the separation efficiency of 66.6 % was achieved. The optimum purity efficiency of 70 % was achieved for 1:100 dilution times. 相似文献
72.
Murad Khan Awais Ahmad Shehzad Khalid Syed Hassan Ahmed Sohail Jabbar Jamil Ahmad 《Multimedia Tools and Applications》2017,76(23):24649-24674
Vertical handover gain significant importance due to the enhancements in mobility models by the Fourth Generation (4G) technologies. However, these enhancements are limited to specific scenarios and hence do not provide support for generic mobility. Similarly, various schemes are proposed based on these mobility models but most of them are suffered from the high packet loss, frequent handovers, too early and late handovers, inappropriate network selection, etc. To address these challenges, a generic vertical handover management scheme for heterogeneous wireless networks is proposed in this article. The proposed scheme works in three phases. In the first phase, a handover triggering approach is designed to identify the appropriate place for initiating handover based on the estimated coverage area of a WLAN access point or cellular base station. In the second phase, fuzzy rule based system is designed to eliminate the inappropriate networks before deciding an optimal network for handover. In the third phase, a network selection scheme is developed based on the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) decision mechanism. Various parameters such as delay, jitter, Bit Error Rate (BER), packet loss, communication cost, response time, and network load are considered for selecting an optimal network. The proposed scheme is tested in a mobility scenario with different speeds of a mobile node ranging from very low to very high. The simulation results are compared with the existing decision models used for network selection and handover triggering approaches. The proposed scheme outperforms these schemes in terms of energy consumption, handover delay and time, packet loss, good put, etc. 相似文献
73.
Amino acid propensity score is one of the earliest successful methods used in protein secondary structure prediction. However, the score performs poorly on small-sized datasets and low-identity protein sequences. Based on current in silico method, secondary structure can be predicted from local folds or local protein structure. In biology, the evolution of secondary structure produces local protein structure with different lengths. To precisely predict secondary structures, we propose a derivative feature vector, DPS that utilizes the optimal length of the local protein structure. DPS is the unification of amino acid propensity score and dihedral angle score. This new feature vector is further normalized to level the edges. Prediction is performed by support vector machines (SVM) over the DPS feature vectors with class labels generated by secondary structure assignment method (SSAM) and secondary structure prediction method (SSPM). All experiments are carried out on RS126 sequences. The results from this proposed method also highlight the overall accuracy of our method compared to other state-of-the-art methods. The performance of our method was acceptable specifically in dealing with low number and low identity sequences. 相似文献
74.
Salman A. Al‐Shami Md Rawi Che Salmah Siti Azizah Mohd Nor Abu Hassan Ahmad Nur Adibah Mohd Ishadi Hamady Dieng 《河流研究与利用》2013,29(9):1195-1204
Rapid industrialization and urbanization has led to increasing input of chemical contaminants into the aquatic environment of Malaysia. Despite the threat civilization poses to the biota, there are still very few relevant studies on ecotoxicological testing of river ecosystems. To overcome this knowledge gap, we examined lethal and genotoxic effects of sediments from different rivers of the northern Malaysia against Chironomus kiiensis, a group well represented in the aquatic fauna of this region. We exposed the larvae to sediments from Selama River (SR), Permatang Rawa River (PRR) and Kilang Ubi River (KUR) at various durations (0, 6, 12, 24 and 48 h). The larval mortality was monitored, whereas DNA damage in survivors' cells was determined using the comet assay. Pollution level indexed by the amounts of heavy metals and other organic contaminants in the sediment showed progressive increases from SR to PRR to KUR. Highly polluted sediments (PRR to KUR) were detrimental to C. kiiensis larvae, most of which did not survive following exposure for long periods. DNA analyses revealed greater damages in nuclei derived from larvae maintained on polluted sediments, in particular, those from KUR. The effects on the genomic material of C. kiiensis larvae occurred in a time‐dependent manner, with damage level increasing as exposure time progressed. Our results highlight the genotoxic properties of polluted sediments. More importantly, this study showed that C. kiiensis larvae could respond to different levels of pollution with respect to exposure time. It is concluded that C. kiiensis larvae is a potential candidate for river ecotoxicological monitoring. Copyright © 2012 John Wiley & Sons, Ltd. 相似文献
75.
Amin Manouchehrian Mostafa Sharifzadeh Rasoul Hamidzadeh Moghadam Tohid Nouri 《矿业科学技术学报(英文版)》2013,23(4):495-501
Recently, many regression models have been presented for prediction of mechanical parameters of rocks regarding to rock index properties. Although statistical analysis is a common method for developing regression models, but still selection of suitable transformation of the independent variables in a regression model is difficult. In this paper, a genetic algorithm (GA) has been employed as a heuristic search method for selection of best transformation of the independent variables (some index properties of rocks) in regression models for prediction of uniaxial compressive strength (UCS) and modulus of elasticity (E). Firstly, multiple linear regression (MLR) analysis was performed on a data set to establish predictive models. Then, two GA models were developed in which root mean squared error (RMSE) was defined as fitness function. Results have shown that GA models are more precise than MLR models and are able to explain the relation between the intrinsic strength/elasticity properties and index properties of rocks by simple formulation and accepted accuracy. 相似文献
76.
ABSTRACT In this paper, the finite element technique used in the analysis and design of water distribution networks will be presented. The method was applied successfully to the solution of three different networks. In order to demonstrate the feasibility of the approach and to show some merits and demerits of the finite element method, a comparison was made on a digital computer with the standard Hardy Cross method. In all cases the finite element method was shown to provide superior performance. Moreover, the programmes were run on three different machines [Wang vs 100, Apple IIe, and IBM micro-computer] to show the effect of increasing storage capacity, machine accuracy, and time saving. 相似文献
77.
Raheel Hassan Syed Jasmina Pazardzievska Julien Bourgeois 《The Journal of supercomputing》2012,62(2):804-827
Due to the extensive growth of grid computing networks, security is becoming a challenge. Usual solutions are not enough to prevent sophisticated attacks fabricated by multiple users especially when the number of nodes connected to the network is changing over the time. Attackers can use multiple nodes to launch DDoS attacks which generate a large amount of security alerts. On the one hand, this large number of security alerts degrades the overall performance of the network and creates instability in the operation of the security management solutions. On the other hand, they can help in camouflaging other real attacks. To address these issues, a?correlation mechanism is proposed which reduces the security alerts and continue detecting attacks in grid computing networks. To obtain the more accurate results, a?major portion of the experiments are performed by launching DDoS and Brute Force (BF) attacks in real grid environment, i.e., the Grid??5000 (G5K) network. 相似文献
78.
Two modified electrodes (Pb/PbO2 and C/PbO2) were prepared by electrodepositing a lead oxide layer on lead and carbon sub-strates. These modified electrodes were used as anodes for the generation of sodium hypochlorite (NaOCl) from sodium chloride solution. Different operating conditions and factors affecting the treatment process of NaOCl generation, including current density, pH values, con-ductive electrolytes, and electrolysis time, were studied and optimized. By comparison the C/PbO2 electrode shows a higher efficiency than the Pb/PbO2 electrode for the generation of NaOCl. 相似文献
79.
80.
Yuanxin Zhou Mohammed A. Baseer Hassan Mahfuz Shaik Jeelani 《Materials Science and Engineering: A》2006,420(1-2):63-71
This paper presents an analytical approach which combines the modified shear-lag model and Monte Carlo simulation technique to simulate the tensile failure process of unidirectional T700 carbon reinforced composite. Two kinds of matrix were investigated in the present paper, one is neat epoxy and the other one is SiC nano-particle filled epoxy. In the model, the strength of the fiber elements is randomly allocated by the Monte Carlo method, the elastic properties of the matrix elements and the friction after the interfaces breakage are definitely allocated. Using this model, the deformation, damage and failure process of the composite are simulated on the microscopic level, the tensile stress–strain relationship is well predicted. The relationship between mechanical properties of the fiber, matrix and composites was discussed. The analysis also shows that, compared with the neat system, nano-phased composite exhibits 10% improvement in tensile strength, which agrees with the experimental data. 相似文献