A new method for the electro-optical measuring of fast high voltage pulses

This report describes a new method for measuring fast high voltage electric pulses based on one particular application of the Kerr effect. This work was carried out in order to further the development of optical particle detectors. At the present time with our method, the minimum risetime of the measured pulse reaches the nanosecond domain while the maximum voltage is limited only by the physical dimension of the electro-optical transducer.The measuring principle chosen requires a new calibration method in order to reconstruct the observed signal.The use of nitrobenzol as the active liquid allows the continuous modification of the cell sensitivity over a ratio of 1 to 3 without changing the geometry of the cell.     

An interregional labour market model incorporating vacancy chains and social security

This paper deals with three aspects of interregional demo-economic models which are important with respect to the analysis of regional labour market developments. First, attention is paid to forecasts of the exogenous regional variables, such as investments, exports, etc. Because data at the regional level are usually scarce, it is suggested to make these projections by means of a top-down model. Second, the social security sector is incorporated in the model framework, because changes in social security benefits, which are common in many Western countries nowaday, usually have substantial impacts on regional economic and demographic structures. Third, a vacancy chain model instead of a simple employment growth equation is tied to the standard demo-economic model framework. In this way not only employment growth but also migration, job mobility and related income effects can be taken into account.     

Understanding TES microcalorimeter noise and energy resolution

We have performed numerical calculations of the noise in voltage-biased superconducting transition edge-based X-ray microcalorimeters, using a finite-element model. Details of the model are discussed, as well as results for different absorber geometries. The results are in agreement with an analytical model and show that the amount of internal thermal fluctuation noise can be reduced by using a segmented absorber. The simulation also agrees well with experimental data, which, for our detectors, contain no major unidentified noise sources. Furthermore, the discrepancy between the (small-signal) theoretical and the measured energy resolutions for 5.9 keV X-rays, for our sensors typically a factor of 2, is explained by a more accurate modelling of the sensor responsivity, taking into account the large signal behaviour.     

QFT control design for an approximately linearized pneumatic positioning system

A block‐oriented approximate feedback linearization for control of a pneumatic cylinder positioning system is introduced and a rather detailed discussion is presented on the uncertain linearization residual characterization. It is shown that making use of the characterized gain–phase information of the linearized system leads to a more reasonable trade‐off between performance and stability in the QFT control design and thus results in high control performance. Simulation and experimental results are shown. Copyright © 2003 John Wiley & Sons, Ltd.     

Evaluation of Digitally Encoded Layer‐by‐layer Coated Microparticles as Cell Carriers

To obtain more biologically relevant data there is a growing interest in the use of living cells for assaying the biological activity of unknown chemical compounds. Density ‘multiplex’ cell‐based assays, where different cell types are mixed in one well and simultaneously investigated upon exposure to a certain compound are beginning to emerge. To be able to identify the cells they should be attached to microscopic carriers that are encoded. This paper investigates how digitally encoded microparticles can be loaded with cells while keeping the digital code in the microcarriers readable. It turns out that coating the surface of the encoded microcarriers with polyelectrolytes using the layer‐by‐layer (LbL) approach provides the microcarriers with a ‘highly functional’ surface. The polyelectrolyte layer allows the growth of the cells, allows the orientation of the cell loaded microcarriers in a magnetic field, and does not hamper the reading of the code. It has further been shown that the cells growing on the polyelectrolyte layer can become transduced by adenoviral particles hosted by the polyelectrolyte layer. It is concluded that the digitally encoded microparticles are promising materials for use in biomedical and pharmaceutical in‐vitro research where cells are used as tools.     

Optimal and reinforced robustness designs of fuzzy variable structure tracking control for a piezoelectric actuator system

In this paper, a piezoelectric actuator (PEA) system is approximated by N subsystems, which are described by pulse transfer functions. The approximation error between the PEA system and the fuzzy linear pulse transfer function system is represented by additive nonlinear time-varying uncertainties in every subsystem. First, a dead-beat to the switching surface for every ideal subsystem is designed. It is called the "variable structure tracking control". The output disturbance of the ith subsystem is caused by the approximation error of fuzzy-model and the interaction dynamics resulting from other subsystems. In general, it is not small. Then, the H/sup /spl infin//-norm of the sensitivity function between the switching surface and the output disturbance is minimized. It is the "optimal robustness". Although the effect of the output disturbance is attenuated, a better performance can be reinforced by a switching control which is based on the Lyapunov redesign. This is the final step for the robustness design of control, which is "reinforced robustness". The stability of the overall system is verified by Lyapunov stability theory. Experimental work of a PEA system was carried out to confirm the validity of the proposed control.