焙烧温度对Fe-Mn催化剂结构和合成低碳烯烃性能的影响

在不同的焙烧温度下制备了Fe-Mn沉淀型催化剂,以CO加氢合成低碳烯烃为模型反应在固定床反应器上对催化剂的反应性能进行了考察,并借助X射线物相分析、N2物理吸附、程序升温还原等表征手段对催化剂进行了表征。实验结果表明,随着焙烧温度的升高,催化剂中α-Fe2O3晶粒增大,催化剂比表面积减小。在CO加氢反应中,焙烧温度的升高明显地提高了催化剂的运行稳定性,降低了CH4的选择性,促进了链增长。450℃条件下焙烧的催化剂烯烃选择性最高,有较高的低碳烯烃收率。     

浅析“禁止重复授权”原则——我国专利法如何避免“重复授权”

"禁止重复授权原则"是我国专利制度的基本原则,分析了我国专利法、实施细则关于"禁止重复授权"的规定,结合审查实践中所遇到的实际情况,较为全面地介绍了我国专利法如何避免"重复授权"的具体操作方式,为申请人如何保护自己的利益提供了帮助。     

Conjugated Polymer Based Nanoparticles as Dual‐Modal Probes for Targeted In Vivo Fluorescence and Magnetic Resonance Imaging

A facile strategy is developed to synthesize dual‐modal fluorescent‐magnetic nanoparticles (NPs) with surface folic acid by co‐encapsulation of a far‐red/near‐infrared (FR/NIR)‐emissive conjugated polymer (PFVBT) and lipid‐coated iron oxides (IOs) into a mixture of poly(lactic‐co‐glycolic‐acid)‐poly(ethylene glycol)‐folate (PLGA‐PEG‐FOL) and PLGA. The obtained NPs exhibit superparamagnetic properties and high fluorescence, which indicates that the lipid coated on IOs is effective at separating the conjugated polymer from IOs to minimize fluorescence quenching. These NPs are spherical in shape with an average diameter of ≈180 nm in water, as determined by laser light scattering. In vitro studies reveal that these dual‐modal NPs can serve as an effective fluorescent probe to achieve targeted imaging of MCF‐7 breast cancer cells without obvious cytotoxicity. In vivo fluorescence and magnetic resonance imaging results suggest that the NPs are able to preferentially accumulate in tumor tissues to allow dual‐modal detection of tumors in a living body. This demonstrates the potential of conjugated polymer based dual‐modal nanoprobes for versatile in vitro and in vivo applications in future.     

大中型沼气工程生命周期能效评价

基于生命周期评价理论,对山东某沼气工程进行了能效评价。研究得出,该沼气工程生命周期总能耗(折合标准煤)为561 471.47 kg/a(11.54 kg/GJ),其中,化石能耗占96.62%;节能量为1 100 271.42 kg/a;生命周期综合能源利用率为61.82%;生命周期新水耗量为26 552.56 m3/a。利用Sima Pro 8.0.2软件,采用生态指数法分析得出,该沼气工程生命周期产生的环境影响为364.303 3 k Pt/a(7.480 5 Pt/GJ);通过情景分析得出,沼气工程的环境损害减弱能力为191.805 2 k Pt/a(34.49%)。针对该沼气工程存在的一些问题,提出了开发沼液综合利用技术等建议,为提高沼气工程能效、减少环境损害提供理论参考。     

面向产品快速设计的有限理性用户建模方法

用户满意是工业产品设计成功的标志,然而用户与设计师对产品的认知与要求也存在着显著差异。分析了有限理性用户建模的依据,提出了面向产品快速设计的有限理性用户建模模型,从提高产品方案的设计效率和用户满意度出发,探讨了用户模型的分析方法,提出了面向产品快速设计的有限理性用户建模理论与方法体系。     

萃智(TRIZ)理论应用,创新的“点金术”

萃智理论就是由根里奇·阿奇舒勒通过对250万份发明专利的分析研究,总结归纳的一套发明创新理论,该理论由阿奇舒勒在20世纪40年代创立,总结了企业产品发展进化的客观规律,指导人们创造性地解决实际科研生产中遇到的技术难题。阐述企业应用萃智理论创新方法指导研发,成功研发出甘蔗收获机械系列产品投入市场应用并获得市场认可。     

Simulink应用于PLC运动控制系统初探

本文以交流伺服系统的三环控制为例,介绍通过Simulink平台进行建模仿真,使用Simulink PLC Coder生成符合IEC61131-3标准的结构化文本,继而导入PLC运动控制系统,运行结果和Simulink仿真结果一致。提供了一种复杂控制算法从Simulink仿真平台到PLC系统的自动化转化方法,对PLC系统工程实施有一定的借鉴作用。     

Identification and characterization of a novel angiotensin I-converting enzyme inhibitory peptide (ACEIP) from silkworm pupa

The angiotensin I-converting enzyme inhibitory peptide (ACEIP) was isolated and characterized from silkworm pupae and purified using Sephadex G-25 gel filtration. The structure and physicochemical properties of pupa ACEIP were analyzed. The α-P₃ fraction exhibited the most potent ACE inhibitory activity. After purification via semi-preparative reverse-phase HPLC (RP-HPLC) and HPLC, the α-P₃-6-b component was revealed to have the highest ACE inhibitory activity (IC₅₀=28.3 μg/mL). Edman degradation revealed a Val-Glu-Ile-Ser amino acid sequence in which novel active sequences were identified. Physicochemical property testing showed that purified pupa ACEIP exhibits good solubility, heat resistance, and acid resistance that all indicate ACEIP derived from silkworm pupa is an excellent food-derived ACEIP.     

赤霞珠葡萄籽多酚低共熔溶剂提取及其抗氧化活性研究

研究不同绿色低共熔溶剂（DESs）结合超声辅助对赤霞珠葡萄皮渣中葡萄籽多酚提取及提取物体外抗氧化活性的影响。结果表明,部分DESs对总酚及总黄酮的提取量显著优于传统提取溶剂（水、体积分数为80%乙醇、体积分数为80%甲醇）（P＜0.05）。提取总酚和总黄酮最优的DESs分别为氯化胆碱-乳酸和脯氨酸-乙酰丙酸。绝大部分DESs提取物中单体酚的含量显著高于传统提取溶剂（P＜0.05）。氯化胆碱-乙二醇提取物DPPH自由基清除能力最强,脯氨酸-乙二醇提取物ABTS+自由基清除能力最强,均显著高于传统溶剂提取物（P＜0.05）。皮尔森相关性分析结果表明,赤霞珠葡萄籽DESs提取物中总酚、儿茶素、表儿茶素含量与其体外抗氧化能力呈显著正相关（P＜0.05）。