Advances in the management of bronchial asthma

The ultrastructure of rat precorneal tear film was visualized by the quick freezing-freeze substitution (QF-FS) method and the conventional fixative method under the scanning electron microscope (SEM). In the QF-FS method, the eyeballs of rats were quickly frozen with an isopentane-propane mixture cooled by liquid nitrogen applied directly to the eyes. After enucleating the eyes and fracturing the frozen corneas, the corneas were prepared for SEM observation. In contrast to the conventional fixative method, by which the microvilli of the surface epithelial cells could be visualized clearly, a very thin membrane-like structure was observed to cover the corneal surface in the eyes prepared by the QF-Fs method. Between the membrane-like structure and corneal surface, a homogeneous and fine network-like structure was observed. The results suggest that the structure of the tear film might be different from the one we have believed to consist of three layers until now. The QF-FS method is considered to be useful for the morphological study of the precorneal tear film.     

上海市吴淞工业区大气PM2.5水溶成分的元素分析及细胞毒性研究

通过ICP-MS测定了上海市吴淞地区大气PM2.5水溶成分金属元素含量,通过四唑盐(MTT)测定细胞存活率,通过超氧化歧化酶(SOD)和丙二醛(MDA)两个指标测定细胞氧化损伤,琼脂糖凝胶电泳测定细胞内DNA损伤,流式细胞仪(Flow cytometry)检测细胞凋亡和周期等实验研究了大气PM2.5水溶成分的细胞毒性.实验结果表明:PM2.5可溶成分中Zn元素含量最高,PM2.5在一定浓度范围内能导致细胞死亡,引起细胞的氧化损伤,影响DNA的复制,阻碍细胞增殖,但没有诱导细胞凋亡.PM2.5中可溶金属离子对细胞毒性表现为联合作用.     

水布垭水电站右岸防淘墙设计方案施工优化

水布垭水电站右岸防淘墙工程规模大、工程地质条件复杂、施工工期紧、危险性大,由于施工中参建各方的共同努力,对施工设计方案进行了优化,先后克服了地质条件差、塌方、大流量渗水等难题,从而确保了防淘墙全线提前完工,为电站尾水系统施工赢得了时间,也为水布垭水电站按期发电奠定了坚实的基础。     

钍归-化在盆地γ能谱资料处理中的应用

在应用γ能谱资料寻找砂岩型铀矿的过程中，要尽可能地消除非矿化因素引起的干扰，提取与铀矿化有关的信息。介绍了钍归-化的原理及特点，采用与矿化有关的元素迁移信息的钍归-化方法，分析了二连盆地东部的γ能谱资料，揭示了该区放射性元素的分布特征、地球化学作用和后期铀元素的迁移与富集。结合其他地质资料，分析了钾剩差的变异区（正、负高值区）及铀剩差正高值区形成的原因，同时指出了经过钍归-化处理所得到的铀剩差正高值区应为氧化与还原作用过渡带的直接指示，也是该区进一步寻找砂岩型铀矿的重要标志。