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RC Hickson WW Heusner WD Huss DE Jackson DA Anderson DA Jones AT Psaledas 《Canadian Metallurgical Quarterly》1976,8(3):191-195
The practice of sequential incubation in radio-immunoassay of TSH improves the sensitivity and precision without affecting the specificity compared with the method using simultaneous incubation of the constituents of the radio-immunological reaction. The determination of basic levels of TSH is more sensitive and more precise. 相似文献
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Antideuteron-nucleus absorptive cross sections for intermediate to high energies are calculated using an ion-ion optical model. Good agreement with experiment (within 15 percent) is obtained in this same model for mean p-nucleus cross sections at laboratory energies up to 15 GeV. We describe a technique for estimating antinucleus-nucleus cross sections from N mean N data and suggest that further cosmic ray studies to search for antideuterons and other antinuclei be undertaken. 相似文献
886.
Kerr CC Neymotin SA Chadderdon GL Fietkiewicz CT Francis JT Lytton WW 《IEEE transactions on neural systems and rehabilitation engineering》2012,20(2):153-160
Damage to a cortical area reduces not only information transmitted to other cortical areas, but also activation of these areas. This phenomenon, whereby the dynamics of a follower area are dramatically altered, is typically manifested as a marked reduction in activity. Ideally, neuroprosthetic stimulation would replace both information and activation. However, replacement of activation alone may be valuable as a means of restoring dynamics and information processing of other signals in this multiplexing system. We used neuroprosthetic stimulation in a computer model of the cortex to repair activation dynamics, using a simple repetitive stimulation to replace the more complex, naturalistic stimulation that had been removed. We found that we were able to restore activity in terms of neuronal firing rates. Additionally, we were able to restore information processing, measured as a restoration of causality between an experimentally recorded signal fed into the in silico brain and a cortical output. These results indicate that even simple neuroprosthetics that do not restore lost information may nonetheless be effective in improving the functionality of surrounding areas of cortex. 相似文献
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Liver failure and death after exposure to microcystins at a hemodialysis center in Brazil 总被引:5,自引:0,他引:5
EM Jochimsen WW Carmichael JS An DM Cardo ST Cookson CE Holmes MB Antunes DA de Melo Filho TM Lyra VS Barreto SM Azevedo WR Jarvis 《Canadian Metallurgical Quarterly》1998,338(13):873-878
BACKGROUND: Hemodialysis is a common but potentially hazardous procedure. From February 17 to 20, 1996, 116 of 130 patients (89 percent) at a dialysis center (dialysis center A) in Caruaru, Brazil, had visual disturbances, nausea, and vomiting associated with hemodialysis. By March 24, 26 of the patients had died of acute liver failure. METHODS: A case patient was defined as any patient undergoing dialysis at dialysis center A or Caruaru's other dialysis center (dialysis center B) during February 1996 who had acute liver failure. To determine the risk factors for and the source of the outbreak, we conducted a cohort study of the 130 patients at dialysis center A and the 47 patients at dialysis center B, reviewed the centers' water supplies, and collected water, patients' serum, and postmortem liver tissue for microcystin assays. RESULTS: One hundred one patients (all at dialysis center A) met the case definition, and 50 died. Affected patients who died were older than those who survived (median age, 47 vs. 35 years, P<0.001). Furthermore, all 17 patients undergoing dialysis on the Tuesday-, Thursday-, and Saturday-night schedule became ill, and 13 of them (76 percent) died. Both centers received water from a nearby reservoir. However, the water supplied to dialysis center B was treated, filtered, and chlorinated, whereas the water supplied to dialysis center A was not. Microcystins produced by cyanobacteria were detected in water from the reservoir and from dialysis center A and in serum and liver tissue of case patients. CONCLUSIONS: Water used for hemodialysis can contain toxic materials, and its quality should therefore be carefully monitored. 相似文献