Movement stability analysis of a pipe string in a thixotropic fluid

Features of movement of a drill pipe string in a well filled with a thixotropic fluid are analyzed taking into account inertial and elastic forces of the rope system. It is shown that processes of fluid structure degradation can lead to nonstationary movement of the pipes. In this case periodic and chaotic auto-oscillations are excited in the system.Bashkir State University, Ufa, Russia. Translated from Inzhenerno-Fizicheskii Zhurnal, Vol. 66, No. 4, pp. 405–411, April, 1994.     

Intracavitary afterloading therapy as a new technique of boost irradiation in anal canal carcinoma

PURPOSE: There are different techniques of boost irradiation in the treatment of patients with anal carcinoma. A new system of applicators is presented, which can be used for an intracavitary afterloading therapy. MATERIAL AND METHODS: Three different applicators are available, the first with a central catheter (K1), a second with 5 semicircular fixed catheters (K2) and an eccentric shield, a third with 8 circular fixed catheters and a central shield (K3). RESULTS: The adequate choice of applicator and catheters takes into consideration the individual localisation and extension of anal carcinoma in planning therapy. Thus, in circular growing tumors, an irradiation of the whole circumference of the anal canal is possible. In non-circular growing tumors, the dose applied in the non-affected part of the anal canal can be reduced to a quarter of the dose applied at the tumor. CONCLUSION: The new system of intracavitary afterloading therapy is a good alternative to previous techniques of boost irradiation in the treatment of anal carcinoma. By means of this technique, irradiation can be highly individualized, the tumor better included and non-affected sections of the anal canal saved.     

First evaluation of a year of ambulatory surgery in urology

Day surgery in urology is in full growth actually. The present report is based on our first 120 patients. Low post-operative complication rate, patients' satisfaction and economical savings are the main factors for the important increase in this type of surgery.     

EFFECT OF STORAGE ON THE RHEOLOGICAL BEHAVIOUR OF BABY FOODS

The effect of storage temperature on rheological behaviour of four varieties of baby foods was studied. After 24-month storage at 15C and 25C, the constant A in Weltman model increased significantly for the vegetables, meat and fish samples, and decreased significantly for the fruit samples. After 24-month storage at 5C and 15C there were no significant changes in flow behavior index, consistency index and yield stress of the Herschel-Bulkley model for the vegetables, meat, fish and fruit samples. Increase in storage temperature decreased the consistency index and yield stress of the fruit samples.     

NMR IMAGING, CALORIMETRIC, and MATHEMATICAL MODELING STUDIES of FOOD FREEZING

Nuclear magnetic resonance imaging (MRI), calorimetry, and temperature measurements were used to monitor cylindrical potato sections frozen at -11C and -42C. MRI showed the advance of the nonsymmetric freezing zone and loss of signal intensity as liquid water turned to ice. Differential calorimetry was used to follow heat removal during transient freezing. Measured times to 95% enthalpy change were 24 min (-42C) and 49 min (-11C), as compared to modeled values of 29 min (-42C) and 100 min (-11C). Times to 95% change in the NMR signal, integrated over the area of the image, were 21 min (-42C) and 56 min (-11C). Changes in NMR signal intensity could be correlated with the amount of unfrozen water remaining after a steady-state had been reached. At -42C, NMR indicated 25% unfrozen water remaining as compared to 26% by calorimetry, and 22% by modeling. At -11C, NMR measured 67% unfrozen water remaining as compared to 48% by calorimetry, and 25% by equilibrium modeling.     

Antibacterial activity of sourdough lactic acid bacteria: isolation of a bacteriocin-like inhibitory substance fromLactobacillus sanfranciscoC57

A total of 232 strains from nine species ofLactobacillusisolated from sourdoughs were screened for antagonistic activity against sourdough-related micro-organisms. Seventy-seven strains on agar medium and 52 in culture supernatants, re-adjusted to pH 6.5 and catalase-treated, showed antagonistic activity. The activities were species and strain specific showing different spectra of inhibition against sourdough lactobacilli. All the strains were inhibitory toBacillus subtilisbut not against sourdough yeasts and moulds.Lactobacillus sanfranciscoandLactobacillus plantarumstrains had the largest inhibitory spectrum. All the antimicrobial compounds produced from strains of different species contained a protein moiety and were differently sensitive to different proteinases. A bacteriocin-like inhibitory substance, which was heat-stable (100°C for 20 min), insensitive to lipase and α-amylase, of a protein nature, with an inhibitory spectrum centred about lactic acid bacteria and a bactericidal or bacteriolytic mode of action was isolated fromLb. sanfranciscoC57. The antimicrobial substance also inhibitedListeria monocytogenes, and was mainly produced in the stationary phase of growth and at pH 4.0–5.0.Lb. sanfranciscoC57 variants, which did not contain the nativec. 17 kbp plasmid, maintained their antagonistic activity, therefore, the gene encoding for the bacteriocin-like inhibitory substance fromLb. sanfranciscoC57 is chromosomally located.     

Acute and chronic fetal hypoxia in monochorionic and dichorionic twins

OBJECTIVE: To assess the risk for acute and chronic fetal hypoxia in twin pregnancies. METHODS: We investigated 50 sets of twins (24-38 weeks' gestation, 660-3200 g birth weight) admitted consecutively to our neonatal intensive care unit. Seventy-six infants were appropriate for gestational age (AGA; tenth to 90th percentile), 20 were small for gestational age (SGA; below the tenth percentile), and four were large for gestational age (above the 90th percentile). Twenty-six singleton AGA term newborns served as controls. Umbilical arterial pH was used as a marker for acute and umbilical venous erythropoietin concentration for chronic fetal hypoxia. The results are given as median followed by quartiles. RESULTS: We identified 40 sets of diamniotic-dichorionic twins and ten sets of diamniotic-monochorionic twins with transplacental vascular shunts. In the second-born twin, umbilical arterial pH was lower (7.29, 7.23-7.33) than in the firstborn (7.31, 7.25-7.34) (P = .03), and the incidence of a low pH (less than 7.20) was higher (19 versus 11%). Two second-born twins and none of the firstborn twins had an umbilical arterial pH less than 7.05. In SGA twins, the erythropoietin concentration was elevated (34.8, 22.8-325 mU/mL) compared with that in AGA twins (16.2, 8.2-26.6 mU/mL) (P < .01). In AGA twins, erythropoietin concentration did not differ from that in AGA singleton newborns (19.6, 14.7-31.6 mU/mL). In 12 of 17 twin sets with weight discordancy greater than 15% and in all five twin sets with weight difference greater than 25%, erythropoietin concentration was higher in the smaller twin. The proportion of infants and of complete sets with elevated erythropoietin levels was higher (P < .01) in monochorionic than in dichorionic pregnancies. CONCLUSION: The second-born twin is at increased risk for acute birth asphyxia. Fetal growth restriction in twin pregnancies is associated with chronic fetal hypoxia. Monochorionic twins are at higher risk for chronic fetal hypoxia than are dichorionic twins.     

Hinokitiol induces differentiation of teratocarcinoma F9 cells

Hinokitiol, a constituent of the wood of Chamaecyparis taiwanensis, was found to induce differentiation of teratocarcinoma F9 cells. When examined by the agar-overlay method, in which expression of plasminogen activator as a differentiation marker protein was detected, this compound exhibited a dose- and time-dependent induction. Induction of differentiation by hinokitiol occurred irreversibly and required its addition for more than 12h. Among its structure-related compounds tested, tropolone and two colchicine-related compounds exerted potent activities comparable to that of hinokitiol. These findings indicate that free tropolone structure in the molecules plays an essential role in inducing differentiation of F9 cells. Hinokitiol showed a strong inhibitory effect of DNA synthesis in very early stages of culture, suggesting that this effect may be responsible for triggering differentiation of F9 cells.     

Detecting delaminations in a composite beam using anti-optimization

The present study proposes a detection technique for delaminations in a laminated beam. The proposed technique optimizes the spatial distribution of harmonic excitation so as to magnify the difference in response between the delaminated and intact beam. The technique is evaluated by numerical simulation of two-layered aluminum beams. Effects of measurement and geometric noise are included in the analysis. A finite element model for a delaminated composite, based on a layer-wise laminated plate theory is used in conjunction with a step function to simulate delaminations     

An anthropocentric approach to knowledge-based preventive maintenance

It is common knowledge today that application of sound manufacturing concepts and techniques will only provide cost-effective, long-term return when manufacturing functions are totally integrated with the operators, maintenance engineers and other associated personnel. This paper presents a human-centred methodology and its associated knowledge-based tool, to utilize equipment failure information for the purpose of machine down-time minimization. Based upon a structured and rigorous assessment of each breakdown, and combined with total employee participation, continuous improvement of maintenance function and operational effectiveness of equipment can be made a reality.