Application potential of bone marrow mesenchymal stem cell (BMSCs) based tissue-engineering for spinal cord defect repair in rat fetuses with spina bifida aperta

Spina bifida aperta are complex congenital malformations resulting from failure of fusion in the spinal neural tube during embryogenesis. Despite surgical repair of the defect, most patients who survive with spina bifida aperta have a multiple system handicap due to neuron deficiency of the defective spinal cord. Tissue engineering has emerged as a novel treatment for replacement of lost tissue. This study evaluated the prenatal surgical approach of transplanting a chitosan–gelatin scaffold seeded with bone marrow mesenchymal stem cells (BMSCs) in the healing the defective spinal cord of rat fetuses with retinoic acid induced spina bifida aperta. Scaffold characterisation revealed the porous structure, organic and amorphous content. This biomaterial promoted the adhesion, spreading and in vitro viability of the BMSCs. After transplantation of the scaffold combined with BMSCs, the defective region of spinal cord in rat fetuses with spina bifida aperta at E20 decreased obviously under stereomicroscopy, and the skin defect almost closed in many fetuses. The transplanted BMSCs in chitosan–gelatin scaffold survived, grew and expressed markers of neural stem cells and neurons in the defective spinal cord. In addition, the biomaterial presented high biocompatibility and slow biodegradation in vivo. In conclusion, prenatal transplantation of the scaffold combined with BMSCs could treat spinal cord defect in fetuses with spina bifida aperta by the regeneration of neurons and repairmen of defective region.     

A relativistic extension of the complex scaling method using oscillator basis functions

We develop the complex scaling method within the relativistic framework by expanding the Dirac spinors in the complete set of eigensolutions of a harmonic oscillator potential, and present the theoretical formalism of describing the discrete bound and resonant states on the same footing. Based on a well established and frequently used model, we demonstrate the utility and applicability of the extended method and examine the stability of the results with respect to the variations of the parameters of the model. Satisfactory agreements are found for all the calculated results in comparison with some other calculations in references. Especially, the present calculation in the nonrelativistic limit gives a consistent result with that in the nonrelativistic calculation.     

现代空间环境中屏风设计理念的拓展和延伸

本文着重论述了在现代空间环境中如何拓展和延伸屏风的设计理念,使其在丰富多元的现代社会中具有更广阔的发展空间,并符合现代人的需求。     

A rough set approach to feature selection based on power set tree

Feature selection is viewed as an important preprocessing step for pattern recognition, machine learning and data mining. Traditional hill-climbing search approaches to feature selection have difficulties to find optimal reducts. And the current stochastic search strategies, such as GA, ACO and PSO, provide a more robust solution but at the expense of increased computational effort. It is necessary to investigate fast and effective search algorithms. Rough set theory provides a mathematical tool to discover data dependencies and reduce the number of features contained in a dataset by purely structural methods. In this paper, we define a structure called power set tree (PS-tree), which is an order tree representing the power set, and each possible reduct is mapped to a node of the tree. Then, we present a rough set approach to feature selection based on PS-tree. Two kinds of pruning rules for PS-tree are given. And two novel feature selection algorithms based on PS-tree are also given. Experiment results demonstrate that our algorithms are effective and efficient.     

医院虚拟化服务器部署

随着医院信息化的发展,需要有一种更有效率的方式来调配管理服务器资源。虚拟化能使服务器的资源被更有效地利用起来。通过虚拟化的技术,能将不适宜放在同一台服务器中的应用整合于一台物理服务器中。通过虚拟化软件的调配,能将一台服务器的资源利用率最大化。虚拟化服务器还能解决由于硬件、环境不足造成的资源紧张,提高医院信息系统管理的效率。     

A comment on “Using locally estimated geodesic distance to optimize neighborhood graph for isometric data embedding”

A geodesic distance-based approach to build the neighborhood graph for isometric embedding is proposed to deal with the highly twisted and folded manifold by Wen et al. [Using locally estimated geodesic distance to optimize neighborhood graph for isometric data embedding, Pattern Recognition 41 (2008) 2226-2236]. This comment is to identify the error in their example and the ineffectiveness of their algorithm.     

Externalizing cognitive maps via map reconstruction and verbal description

Universal Access in the Information Society - Helping blind people to build cognitive maps of an environment is one of the aims of several assistive systems. In order to evaluate such assistive...