焦化汽柴油加氢捕硅剂的制备及性能评价

目的 脱除焦化汽柴油馏分中的有机硅化合物,避免催化剂硅中毒。方法 以拟薄水铝石粉为载体制备原料,镍钼为活性金属组分,采用等体积浸渍法制备了加氢捕硅剂,利用N₂吸附脱附、X射线衍射、吡啶红外光谱、扫描电镜等方法对其进行分析表征,并在200 mL加氢中试装置上考查了捕硅剂的脱硅活性和2 000 h活性稳定性。结果 自主开发的捕硅剂比表面积和孔容较高,酸性适宜,活性金属分布均匀,强度满足工业装置装填要求。捕硅剂的脱硅活性较高,在典型的工业条件下,脱硅率>90%,在2 000 h活性稳定性试验过程中,脱硅率稳定>90%,活性稳定性良好,且具有较高的容硅能力。结论 自主开发的捕硅剂具有广阔的工业应用前景,对清洁燃料的生产及保护装置的长周期稳定运行具有十分重要的意义。     

A hierarchical test methodology for systems on chip

We present a hierarchical test methodology for testing a SOC with heterogeneous cores, including the 1149.1-wrapped, P1500-wrapped, and BIST memory cores. We propose an 1149.1-based hierarchical test manager that also provides P1500 test control signals. This scheme includes a memory BIST interface, providing both serial and parallel access ports for BIST circuits. Our approach offers low area and pin overhead, and high flexibility     

高压直流输电控制保护系统新技术——WIN-TDC

在新一代直流控制保护系统WIN-TDC中,极控、站控和直流保护等核心部分采用了基于64位精简指令集计算机(RISC)、实时操作系统、64位系统总线的工业控制通用平台--SIMATIC-TDC.SIMATIC-TDC的开发环境采用了单一的编程语言,调试软件集成在开发环境中.人机界面采用了通用工控组态软件--WINCC.利用时分复用(TDM)总线技术实现了测量系统的交叉冗余.WIN-TDC已经在澳大利亚的海底电缆直流工程(BASSLINK)中得到了成功的应用.     

Characterization of Inhibitory Capability on Hyperpolarization-Activated Cation Current Caused by Lutein (β,ε-Carotene-3,3′-Diol), a Dietary Xanthophyll Carotenoid

Lutein (β,ε-carotene-3,3′-diol), a xanthophyll carotenoid, is found in high concentrations in the macula of the human retina. It has been recognized to exert potential effectiveness in antioxidative and anti-inflammatory properties. However, whether and how its modifications on varying types of plasmalemmal ionic currents occur in electrically excitable cells remain incompletely answered. The current hypothesis is that lutein produces any direct adjustments on ionic currents (e.g., hyperpolarization-activated cation current, I_h [or funny current, I_f]). In the present study, GH₃-cell exposure to lutein resulted in a time-, state- and concentration-dependent reduction in I_h amplitude with an IC₅₀ value of 4.1 μM. There was a hyperpolarizing shift along the voltage axis in the steady-state activation curve of I_h in the presence of this compound, despite being void of changes in the gating charge of the curve. Under continued exposure to lutein (3 μM), further addition of oxaliplatin (10 μM) or ivabradine (3 μM) could be effective at either reversing or further decreasing lutein-induced suppression of hyperpolarization-evoked I_h, respectively. The voltage-dependent anti-clockwise hysteresis of I_h responding to long-lasting inverted isosceles-triangular ramp concentration-dependently became diminished by adding this compound. However, the addition of 10 μM lutein caused a mild but significant suppression in the amplitude of erg-mediated or A-type K⁺ currents. Under current-clamp potential recordings, the sag potential evoked by long-lasting hyperpolarizing current stimulus was reduced under cell exposure to lutein. Altogether, findings from the current observations enabled us to reflect that during cell exposure to lutein used at pharmacologically achievable concentrations, lutein-perturbed inhibition of I_h would be an ionic mechanism underlying its changes in membrane excitability.     

Effects of PCSK-9 Inhibition by Alirocumab Treatments on Biliary Cirrhotic Rats

Hyperlipidemia and oxidative stress with elevated oxidized low-density lipoprotein (ox-LDL) exacerbate hepatic inflammation and fibrosis. The plasma level of low-density lipoprotein (LDL) is controlled by proprotein convertase subtilisin/kexin 9 (PCSK9). Alirocumab is a monoclonal antibody that decreases LDL via inhibiting PCSK9 function. Apart from lipid-lowering effects, alirocumab exerts anti-inflammation, anti-angiogenesis and anti-oxidant effects. This study aims to investigate the impact of alirocumab treatment on common bile duct ligation (BDL)-induced biliary cirrhotic rats. After a 4-week treatment of alirocumab, the hemodynamic data, blood biochemistry, ox-LDL level, oxidative stress markers, severity of hepatic encephalopathy and abnormal angiogenesis of BDL rats were measured and compared to the control group. BDL rats presented cirrhotic pictures and elevated ammonia, total cholesterol, LDL and ox-LDL levels compared to the control group. Alirocumab decreased plasma levels of total cholesterol, LDL, and oxidative stress markers; however, it did not affect the hemodynamics, liver and renal biochemistry, and the plasma levels of ammonia and ox-LDL. The motor activities, portal-systemic collaterals and mesenteric vascular density were not significantly different between alirocumab-treated and control groups. In addition, it did not affect hepatic inflammation, intrahepatic angiogenesis, liver fibrosis and free cholesterol accumulation in the liver of BDL rats. In conclusion, PCSK9 inhibition by alirocumab treatment ameliorates hyperlipidemia and systemic oxidative stress in biliary cirrhotic rats. However, it does not affect the plasma level of ox-LDL, intrahepatic inflammation and fibrosis. In addition, PCSK9 inhibition has a neutral effect on abnormal angiogenesis and hepatic encephalopathy in biliary cirrhotic rats.     

P波空间斜入射下沥青混凝土面板堆石坝响应特性及面板破坏评价

地震波入射方位和斜入射角度对于沥青混凝土面板堆石坝地震响应结果有着显著影响。本文从地震动传播机制出发,基于波场叠加原理,推导了P波以任意入射方位角和斜入射角空间斜入射下弹性半空间自由场计算公式,建立了P波空间斜入射波动输入模型。以不同应变率下的沥青混凝土单轴动态拉伸试验结果为基础,提出了考虑抗拉强度随应变率实时变化的沥青混凝土面板破坏评价方法。考虑16种不同入射方位角和斜入射角下的P波空间斜入射工况,从面板应力和加速度两方面分析了入射方位角和斜入射角对某实际沥青混凝土面板地震响应特性的影响,并进行了沥青混凝土面板的抗拉破坏评价,分析了静态评价方法与动态评价方法的差异。结果表明,所建立的P波空间斜入射波动输入模型能够准确模拟半空间自由场,波动输入数值解与解析解符合良好;与垂直输入射相比,面板顺水流向、垂直水流向加速度峰值最大分别增加135.9%和92.7%,竖向加速度峰值最大减少68.3%;空间斜输入导致面板动应力增大,主拉应力和主压应力最大分别增加3.6倍和2.7倍,忽略入射方位角和斜入射角可能会严重低估面板的地震响应。传统将静态强度提高30%作为动态强度的面板抗拉破坏判别方法过于严格,本文提出的考虑应变率效应的沥青混凝土面板破坏评价方法较为符合实际。     

缆型钢丝圈在半钢轿车子午线轮胎中的应用

以245/45R18 100W轮胎为例,研究缆型钢丝圈替代六角形钢丝圈在半钢轿车子午线轮胎中的应用。结果表明,采用缆型钢丝圈生产工艺性能良好,可有效减小轮胎质量,降低滚动阻力,提高抗撞击性能,显著增强轮胎在使用过程中的抗风险能力。     

Sensing Matrix Optimization for Multi-Target Localization Using Compressed Sensing in Wireless Sensor Network

In the multi-target localization based on Compressed Sensing(CS), the sensing matrix’s characteristic is significant to the localization accuracy.To improve the CS-based localization approach’s performance, we propose a sensing matrix optimization method in this paper, which considers the optimization under the guidance of the t%-averaged mutual coherence. First, we study sensing matrix optimization and model it as a constrained combinatorial optimization problem. Second, the t%-averaged mutual ...     

Internal OH? induced cascade quenching of upconversion luminescence in NaYF4:Yb/Er nanocrystals

Internal hydroxyl impurity is known as one of the main detrimental factors affecting the upconversion (UC) efficiency of upconversion luminescence (UCL) nanomat...