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61.
The initiation temperature of methane partial oxidation was markedly lowered by platinum wire placed upstream of a high pressure reactor. Added hydrogen in the reactant gas promoted the methanol selectivity. The radicals formed on the platinum surface were desorbed from it and initiated the reaction. 相似文献
62.
Noriya Izu Haruo Kishimoto Takahisa Omata Takayuki Yao 《Science and Technology of Advanced Materials》2013,14(3-4):443-448
Electrical conductivity σt of metastable κ-CeZrO4 possessing ordered arrangement of Ce and Zr ions in a manner similar to a pyrochlore-type was measured as a function of temperature and time, and compared with tetragonal metastable t′-(Ce0.5Zr0.5)O2 and t′meta-(Ce0.5Zr0.5)O2 phases possessing random arrangement of the cations. The κ disk was prepared by reoxidizing a pyrochlore-type precursor in O2 gas at 873 K. The σt as measured for the κ-CeZrO4 was reproducible as a function of temperatures between 957 and 1190 K. At increasing temperatures above 1233 K, the σt decreased gradually with time due to the phase transition: κ → t′, and became consistent with the t′. Although the κ-CeZrO4 phase is thermodynamically less stable than the t′-(Ce0.5Zr0.5)O2, it was virtually stable up to around 1233 K. It was found from the change in the σt due to the phase transition that the σt(Ce0.5Zr0.5)O2 for the metastable κ-CeZrO4 was an order of magnitude higher than that for the t′ and was similar to that for the σtmeta. It was previously reported that a phase transition, t′ → t′, occurred above 1143 K. The phase transition, κ → t′, accompanied by redistribution of the cations appeared to occur at higher temperatures than that for t′meta → t′ leaving random cation arrangement. 相似文献
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Studies on the nitrite uptake capability of a mutant of Synechococcus sp. strain PCC 7942 lacking the ATP-binding cassette-type nitrate-nitrite-bispecific transporter revealed the occurrence of a nitrite-specific active transport system with an apparent Km (NO2-) of about 20 microM. Similar to the nitrate-nitrite-bispecific transporter, the nitrite-specific transporter was reversibly inhibited by ammonium in the medium. 相似文献
66.
M Ohashi F Kanai T Tanaka KH Lan Y Shiratori Y Komatsu T Kawabe H Yoshida H Hamada M Omata 《Canadian Metallurgical Quarterly》1998,89(4):457-462
The vascular endothelial injury with its consequent activation is actively involved in inflammation and promotion of a procoagulant state, which are likely to be of major importance in the pathogenesis of various disorders, including renal thrombotic microangiopathy. This study briefly reviews the consequences of glomerular endothelial cell injury or activation, as shown by recent experimental data. 相似文献
67.
W Omata H Shibata Y Suzuki S Tanaka T Suzuki K Takata I Kojima 《Canadian Metallurgical Quarterly》1997,241(2):401-406
Previous studies have suggested that the neurotrophins brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) are neuroprotective or neurotrophic for certain subpopulations of hippocampal neurons following various brain insults. In the present study, the expression of BDNF and NT-3 mRNAs in rat hippocampus was examined after traumatic brain injury. Following lateral fluid percussion (FP) brain injury of moderate severity (2.0-2.1 atm) or sham injury, the hippocampi from adult rats were processed for the in situ hybridization localization of BDNF and NT-3 mRNAs using 35S-labeled cRNA probes at post-injury survival times of 1, 3, 6, 24 and 72 h. Unilateral FP injury markedly increased hybridization for BDNF mRNA in the dentate gyrus bilaterally which peaked at 3 h and remained above control levels for up to 72 h post-injury. A moderate increase in BDNF mRNA expression was also observed bilaterally in the CA3 region of the hippocampus at 1, 3, and 6 h after FP injury, but expression declined to control levels by 24 h. Conversely, NT-3 mRNA was significantly decreased in the dentate gyrus following FP injury at the 6 and 24 h survival times. These results demonstrate that FP brain injury differentially modulates expression of BDNF and NT-3 mRNAs in the hippocampus, and suggest that neurotrophin plasticity is a functional response of hippocampal neurons to brain trauma. 相似文献
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S Kawahire M Takeuchi T Gohshi S Sasagawa M Shimada M Takahashi TK Abe T Ueda R Kuwano A Hikawa T Ichimura S Omata T Horigome 《Canadian Metallurgical Quarterly》1997,121(5):881-889
We previously purified and characterized a nuclear localization signal (NLS) binding protein, NBP60, in rat liver nuclear envelopes. In this study, we cloned and sequenced the cDNA of rat NBP60, and predicted an amino acid sequence comprising 620 amino acids. The sequence revealed that NBP60 is a rat homologue of lamin B receptor (LBR), and is 79 and 63% identical in amino acids to human and chicken LBR, respectively. Using three fusion proteins containing different parts of the amino-terminal domain of human LBR, it was shown that the stretch comprising amino acids 1 to 89, which contains a Ser-Arg rich region (RS region), binds to nucleoplasmin and that the binding was inhibited by a common NLS-peptide. These results suggested that the amino-terminal domain of LBR contains an NLS-binding site. Furthermore, it was shown that the stretch comprising amino acids 1 to 53, which does not contain the RS region or the predicted DNA-binding site, binds to Xenopus laevis sperm chromatin. 相似文献
70.
Insulin stimulates guanine nucleotide exchange on Rab4 via a wortmannin-sensitive signaling pathway in rat adipocytes 总被引:1,自引:0,他引:1
Rab4, a member of the Rab family of Ras-related small GTP-binding proteins, has been shown to be associated with GLUT4-containing vesicles and implicated in the insulin action on glucose transport in rat adipocytes. In the present study, we investigated the insulin effects on the guanine nucleotide exchange on Rab4. In electrically permeabilized rat adipocytes, the amount of [35S]guanosine 5'-O-(3-thiotrisphosphate) (GTPgammaS) bound to Rab4 increased in a time-dependent manner during 45 min of the incubation period. Addition of insulin resulted in about a 2-fold stimulation of the binding of [35S]GTPgammaS to Rab4, indicating that insulin stimulated the guanine nucleotide exchange on the GTPase. Pretreatment of the cells with wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase, completely abolished the stimulatory effect of insulin on [35S]GTPgammaS binding to Rab4. Wortmannin also attenuated the nucleotide binding to Rab4 in the basal cells, suggesting that phosphatidylinositol 3-kinase activity may be essential for regulation of guanine nucleotide exchange on the GTPase and insulin may up-regulate the exchange activity by stimulating the lipid kinase. Insulin-induced subcellular redistribution of Rab4 from the microsomal fraction to the soluble fraction was also inhibited by wortmannin. These results suggest that insulin stimulates the guanine nucleotide exchange on Rab4 via a phosphatidylinositol 3-kinase-dependent signaling pathway and that Rab4 is one of possible targets of insulin action on intracellular vesicle traffic in rat adipocytes. 相似文献