Influence of Hydroxypropyl Methylcellulose and of Manufacturing Technique on in Vitro Performance of Selected Antacids

Factors affecting the performance of antacids F-MA 11, dihydroxy aluminum aminoacetate, magaldrate and magnesium hydroxide were studied in vitro using Schaub's acid neutralization test, a modified Reheis reaction velocity test and the USP test. From the results obtained it was evident that type and combination of antacid, the adjuvants and formulation techniques used in preparation of antacids affect their performance. The USP preliminary antacid test and acid neutralization test are not optimal in vitro tests to evaluate in vitro onset and duration of action of antacids.     

XML data update management in XML-enabled database

With the increasing demand for a proper and efficient XML data storage, XML-Enabled Database (XEnDB) has emerged as one of the popular solutions. It claims to combine the pros and limit the cons of the traditional Database Management Systems (DBMS) and Native XML Database (NXD). In this paper, we focus on XML data update management in XEnDB. Our aim is to preserve the conceptual semantic constraints and to avoid inconsistencies in XML data during update operations. In this current era when XML data interchange mostly occurs in a commercial setting, it is highly critical that data exchanged be correct at all times, and hence data integrity in XML data is paramount. To achieve our goal, we firstly classify different constraints in XML documents. Secondly, we transform these constraints into XML Schema with embedded SQL annotations. Thirdly, we propose a generic update methodology that utilizes the proposed schema. We then implement the method in one of the current XEnDB products. Since XEnDB has a Relational Model as the underlying data model, our update method uses the SQL/XML as a standard language. Finally, we also analyze the processing performance.     

Ultrafast IR Laser Writing of Strong Bragg Gratings Through the Coating of High Ge-Doped Optical Fibers

Strong fiber Bragg gratings were written through the standard polymer coatings of "off-the-shelf" high numerical aperture single-mode optical fibers after a few seconds exposure with femtosecond pulse durations of infrared radiation through a phase mask. While writing through the acrylate coating, we obtained index modulations of up to 1.4 x 10^-3 and 7 x 10^-4 with and without H₂ -loading, respectively.     

DefibViz: A Visualization Tool for the Assessment of Electrode Parameters on Transthoracic Defibrillation Thresholds

DefibViz is a software application developed for defibrillation simulation and visualization. It exploits both surface techniques and methods for the interactive exploration of volumetric datasets for the analysis of transthoracic defibrillation simulation results. DefibViz has a graphical user interface for the specification of the shape, size, position, and applied voltage of a defibrillator's electrodes. An option is provided for using 3D slice plane widgets, which operate on the volumetric datasets, such that the distribution of the voltage gradient induced by an electric shock can be visually inspected in various tissues throughout the myocardium and torso. One goal of DefibViz is to enhance understanding of how electrode parameters relate to the change of the voltage gradient distribution throughout the heart, which may help lead to optimal defibrillator design. DefibViz is significant, in that, it is built by using an open-source graphics and visualization framework providing a platform for subsequent modifiability and extensibility. Moreover, it integrates simulation and visualization techniques, which previously required the running of several independent software executables, into an enhanced, seamless, and comprehensive software application.     

The Silicon Backplane Design for an LCOS Polarization-Insensitive Phase Hologram SLM

Polarization-insensitivity is achieved in a reflective spatial light modulator by laying a quarter-wave plate (QWP) at the incident wavelength directly over the mirror pixels of a silicon backplane, and forming a nematic Freedrickcz cell over the QWP to modulate the reflected phase. To achieve the highest drive voltage from the available silicon process, a switched voltage common front electrode design is described, with variable amplitude square wave drive to the pixels to maintain constant root-mean-square drive and minimize phase fluctuations during the dc balance refresh cycle. The silicon has been fabricated and liquid-crystal-on-silicon cells both with and without the QWP assembled; applications include optically transparent switches for optical networks, beam steering for add-drop multiplexers for wavelength-division-multiplexing telecommunications, television multicast, and holographic projection.     

Progress toward roll-to-roll processing of inorganic monolithic electrochromic devices on polymeric substrates

As electrochromic device (ECD) emerges into the market, the necessity of cost reduction via high-throughput manufacturing is unavoidable. Inorganic monolithic ECD has compatibility in its manufacturing steps, allows continuous processing and hence low-cost ECD. A roll-to-roll (R2R) production is the industrial standard for high-throughput processing and was chosen to synthesize ECD on polymeric substrates. Preliminary success by implementing methods compatible to the aforementioned R2R processing has been achieved; however, continuous test-runs on an R2R machine are still limited.     

A comparative study on the effect of VUV radiation in plasma SiOx-coated polyimide and polypropylene films

Wettability of polyimide (PI) and polypropylene (PP) films have been improved using SiO_x-like thin layers deposited from a mixture of hexamethyldisiloxane (HMDSO) and oxygen in a microwave distributed electron cyclotron resonance plasma reactor. The films wettability evolution behaviors were evaluated through the results of contact angle measurements, atomic force microscopy (AFM) and X-ray photoelectron spectroscopy (XPS). The plasma depositions of SiO_x thin layers in presence of VUV radiation induce a contact angle decrease to about 7° and 35° for PI and PP films, respectively. XPS data showed that such difference in wettability is attributed to the increase of hydrophilic group's proportion at the surface of coated PI films due to VUV irradiation. AFM images showed that the PI surface topography remains relatively smooth when coated in presence of VUV radiation. However, in the case of PP films, AFM images revealed the growth of irregular structure due to a substrate etching effect supported by VUV radiation. For polymers coated without VUV irradiation, the deconvolution of the C1s peaks showed a significant decrease of CO bonds for both PI and PP substrates.     

Mechanical State Estimation for Overhead Transmission Lines With Level Spans

Electric power transmission lines face increased threats from malicious attacks and natural disasters. This underscores the need to develop new techniques to ensure safe and reliable transmission of electric power. This paper deals with the development of an online monitoring technique based on mechanical state estimation to determine the sag levels of overhead transmission lines in real time and hence determine if these lines are in normal physical condition or have been damaged or downed. A computational algorithm based on least squares state estimation is applied to the physical transmission line equations to determine the conductor sag levels from measurements of tension, temperature, and other transmission line conductor parameters. The estimated conductor sag levels are used to generate warning signals of vertical clearance violations in the energy management system. These warning signals are displayed to the operator to make appropriate decisions to maintain the line within the prescribed clearance limits and prevent potential cascading failures.      

Optimal synthesis of tunable elastic wave-guides

Topology optimization, or control in the coefficients of partial differential equations, has been successfully utilized for designing wave-guides with precisely tailored functionalities. For many applications it would be desirable to have the possibility of drastically altering the wave-guiding properties of a device “on the fly,” in a controllable manner as an influence of some external input. This would enable wave-guides with highly non-linear input-output mappings, such as for example controllable wave switches.In this paper, we propose using finite elastic pre-straining for the purpose of tuning a wave-guide. In order to systematically formulate and solve the wave-guide synthesis problems we utilize mathematical programming methods in conjunction with topology optimization for parametrizing the design space. The resulting extremal problem is, from a practical point, equivalent to finding an optimal subdivision of a given control volume into two disjoint subsets occupied by two different materials, normally resulting in a highly heterogeneous elastic body with desired wave-guiding functionalities in the original and finitely deformed configurations.The proposed methodology is illustrated with numerical examples.