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81.
82.
Prateeksha Prateeksha Vivek Sharma Nemkumar Nagpoore Vishwjeet Jadaun Chandana Rao Brahma Singh 《Advanced functional materials》2023,33(28):2214852
Microbial biofilm formation on implantable devices causes chronic infections that cannot be treated with existing antimicrobials. Quorum sensing inhibitors (QSIs) have recently emerged as novel antimicrobials for the prevention of biofilm formation. But blocking QS alone is insufficient to inhibit biofilm-associated chronic infections. Herein, chitosan hollow nanospheres are capped by bacteria-responsive β-casein to form a synergistic antifouling nanosystem consisting of a QSI and bactericide. β-casein is degraded by protease in a bacteria-colonized microenvironment in situ thus, QSI and bactericide are released sequentially. The release of QSI sensitises bacteria effectively through reduction of surface hydrophobicity, eDNA content, and lipopolysaccharide production in biofilms, amplifying the chemotherapeutic action of the bactericide. Compared to the uncoated surface, the coated surface inhibits biofilm formation and removes preformed biofilms of Pseudomonas aeruginosa PAO1 and methicillin-resistant Staphylococcus aureus by 1.8 logs and 1.9 logs of biomass inhibition, respectively. The coated catheters are found to stay clean for 30 days under artificial urine flow, while the uncoated catheters are clogged by bacterial biofilms within 5 days. Finally, the long term antifouling activity in vivo is confirmed. Overall, the nanosystem is devoted to making urinary catheters resistant to bacterial biofilm formation for the long term. 相似文献
83.
84.
S. Prasanna G. Krishnendu S. Shalini P. Biji G. Mohan Rao S. Jayakumar R. Balasundaraprabhu 《Materials Science in Semiconductor Processing》2013,16(3):705-711
Thin films of alumina (Al2O3) were deposited over Si 〈1 0 0〉 substrates at room temperature at an oxygen gas pressure of 0.03 Pa and sputtering power of 60 W using DC reactive magnetron sputtering. The composition of the as-deposited film was analyzed by X-ray photoelectron spectroscopy and the O/Al atomic ratio was found to be 1.72. The films were then annealed in vacuum to 350, 550 and 750 °C and X-ray diffraction results revealed that both as-deposited and post deposition annealed films were amorphous. The surface morphology and topography of the films was studied using scanning electron microscopy and atomic force microscopy, respectively. A progressive decrease in the root mean square (RMS) roughness of the films from 1.53 nm to 0.7 nm was observed with increase in the annealing temperature. Al–Al2O3–Al thin film capacitors were then fabricated on p-type Si 〈1 0 0〉 substrate to study the effect of temperature and frequency on the dielectric property of the films and the results are discussed. 相似文献
85.
浅层油气运聚理论与渤海大油田群的发现 总被引:3,自引:0,他引:3
渤海油区年产原油3 000×10~4t,约占中国海洋石油产量的70%。渤海油区位于渤海湾新生代陆内裂谷盆地的中东部,勘探面积约4.5×104km2。渤海油区具有鲜明的石油地质特征:著名的郯庐大断裂纵贯渤海,新近纪断裂活动强烈,促进石油的纵向运移,但不利于油藏的保存;中新世—上新世发育河湖相沉积,上部储-盖组合广泛分布,为浅层石油富集创造了条件;古近系生油岩埋藏深,新近系储-盖层较浅,石油垂向运移距离远,运移途径复杂。针对渤海复杂的石油地质条件,经过20年认识—实践—再认识的探索,提出1大断裂-砂体"中转站"模式运移能力强、2小断层及走滑断裂运移油气能力弱、3地层—断层组合关系控制油气富集部位、4临界盖层控制断裂活动带油田形成、5圈闭汇油面积大小决定油田规模、6主力油田展布可分为凸起与凹陷富集型、7小凸起上的披覆背斜利于形成大油田7项创新学术思想,构成了浅层油气运聚理论并指导勘探,渤海勘探团队在短期内高效发现了7个大油田、17个中型油田,共27×10~8 m~3地质储量,奠定了中国第二大油区的储量基础。 相似文献
86.
To obtain highly conductive buried layers in InP:Fe, MeV energy Si, S, and Si/ Simplantations are performed at 200°C. The
silicon and sulfer implants gave 85 and 100 percent activation, respectively, for a fluence of 8 × 1014 cm−2. The Si/S co-implantation also gave almost 100 percent donor activation for a fluence of 8 × 1014 cm−2 of each species. An improved silicon donor activation is observed in the Si/S co-implanted material compared to the material
implanted with silicon alone. The peak carrier concentration achieved for the Si/S co-implant is 2 × 1019 cm3. The lattice damage on the surface side of the profile is effectively removed after rapid thermal annealing. Multiple-energy
silicon and sulfur implantations are performed to obtain thick and buried n+ layers needed for microwave devices and also hyper-abrupt profiles needed for varactor diodes. 相似文献
87.
Two concepts of communication network reliability are considered. The first one, the ‘s-t’ reliability, is relevant for communication between a source station and a terminal station as in the case of a two way telephone communication. The second one, the overall reliability, is a measure of simultaneous connectedness among all stations in the network. An algorthm is presented which selects the optimal set of links that maximizes the overall reliability of the network subject to a cost restriction, given the allowable node-link incidences, the link costs and the link reliabilities. The algorithm employs a variaton of the simulated annealing approach coupled with a hierarchical strategy to achieve the gobal optimum. For complex networks, the present algorithm is advantageous over the traditional heuristic procedures. The solutions of two representative example network optimization problems are presented to illustrate the present algorithm. The potential utilization of parallel computing strategies in the present algorithm is also identified. 相似文献
88.
本文提出了适于三种序号的Chrestenson函数序列的复制方法,对其复制过程进行了数学分析,并指出当Chrestenson函数退化为Walsh函数时,此方法即为复制理论中的平移复制方法。 相似文献
89.
Rao Y.J. Kalli K. Brady G. Webb D.J. Jackson D.A. Zhang L. Bennion I. 《Electronics letters》1995,31(12):1009-1010
A prototype fibre-optic system using interferometric wavelength-shift detection, capable of multiplexing up to 32 fibre-optic Bragg grating strain and temperature sensors with identical characteristics, has been demonstrated. This system is based on a spatially multiplexed scheme for use with fibre-based low-coherence interferometric sensors, reported previously. Four fibre-optic Bragg grating channels using the same fibre grating have been demonstrated for measuring quasi-static strain and temperature 相似文献
90.
Transient scattering (transverse electric case) by two-dimensional cylinders, both open and closed, is investigated using the marching-on-in-time technique. A simple averaging scheme is also presented to control the late-time oscillations. Numerical results are presented for certain representative geometries and compared with inverse Fourier transform techniques. Good agreement is noted in each case 相似文献