Building micro and nanosystems with electrochemical discharges

Since the discovery of the electrochemical discharge phenomenon by Fizeau and Foucault, several contributions have expanded the wide range of applications associated with this high current density electrochemical process. The complexity of the phenomenon, from the macroscopic to the microscopic scales, led since then to experimental and theoretical studies from different research fields. This contribution reviews the chemical and electrochemical perspectives where a mechanistic model based on results from radiation chemistry of aqueous solutions is proposed. In addition applications to micro-machining and fabrication of nanoparticles are discussed.     

Biological properties of iron oxide nanoparticles for cellular and molecular magnetic resonance imaging

Superparamagnetic iron-oxide particles (SPIO) are used in different ways as contrast agents for magnetic resonance imaging (MRI): Particles with high nonspecific uptake are required for unspecific labeling of phagocytic cells whereas those that target specific molecules need to have very low unspecific cellular uptake. We compared iron-oxide particles with different core materials (magnetite, maghemite), different coatings (none, dextran, carboxydextran, polystyrene) and different hydrodynamic diameters (20-850 nm) for internalization kinetics, release of internalized particles, toxicity, localization of particles and ability to generate contrast in MRI. Particle uptake was investigated with U118 glioma cells und human umbilical vein endothelial cells (HUVEC), which exhibit different phagocytic properties. In both cell types, the contrast agents Resovist, B102, non-coated Fe(3)O(4) particles and microspheres were better internalized than dextran-coated Nanomag particles. SPIO uptake into the cells increased with particle/iron concentrations. Maximum intracellular accumulation of iron particles was observed between 24 h to 36 h of exposure. Most particles were retained in the cells for at least two weeks, were deeply internalized, and only few remained adsorbed at the cell surface. Internalized particles clustered in the cytosol of the cells. Furthermore, all particles showed a low toxicity. By MRI, monolayers consisting of 5000 Resovist-labeled cells could easily be visualized. Thus, for unspecific cell labeling, Resovist and microspheres show the highest potential, whereas Nanomag particles are promising contrast agents for target-specific labeling.     

全球电子废物的研究(中)

(续接本刊2007年第7期第36页)2电子废物管理方式和立法提案2.1延伸生产者责任制延伸生产者责任制(EPR)作为废物管理的新模式得以广泛推广。OECD将EPR定义为一种新的环境制度,在该制度下,生产者对其产品的责任延伸到产品销售后的整个生命周期,包括最终处置(OECD,2001)。与污染者付费原则一致,     

The Geometric Dilation of Finite Point Sets

Let G be an embedded planar graph whose edges may be curves. For two arbitrary points of G, we can compare the length of the shortest path in G connecting them against their Euclidean distance. The supremum of all these ratios is called the geometric dilation of G. Given a finite point set, we would like to know the smallest possible dilation of any graph that contains the given points. In this paper we prove that a dilation of 1.678 is always sufficient, and that π/2 = 1.570... is sometimes necessary in order to accommodate a finite set of points.