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21.
The fibrinolytic capacity of patients with acute myocardial infarction (AMI) is known to be impaired. The primary regulatory element of the fibrinolytic system is plasminogen activator inhibitor (PAI). It has been previously observed that there are 2 peaks in the plasma PAI level of AMI patients at 4h and 16h after thrombolytic therapy with recombinant tissue plasminogen activator (rtPA). Lanoteplase/SUN9216 is a mutant tPA with a biological half-life longer than that of rtPA. Thrombolytic therapy with mutant tPA or rtPA was carried out consecutively in 21 patients with AMI (8 patients as the mutant tPA group, and 13 patients as the rtPA group). The recanalization time of the mutant tPA group was significantly faster than that of the rtPA group (16.1 +/- 3.9 min vs 39.6 +/- 4.8 min, p<0.01). The PAI activity at 4h after the initiation of thrombolysis was significantly lower in the mutant tPA group than in the rtPA group (8.74 +/- 5.46IU/L vs 26.74 +/- 3.35 IU/L, p<0.01). There was a one mild peak in serial plasma PAI activity levels 24h after the initiation of thrombolysis. The results suggest that thrombolytic therapy with mutant tPA reduced the impairment of fibrinolytic capacity. The mutant tPA gives faster recanalization and lower PAI activity after successful thrombolysis, compared with rtPA.  相似文献   
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Winner-Take-All (WTA) or K-Winner-Take-All (KWTA) networks have been frequently used as the basic building blocks of complex neural networks. This paper introduces a new selection rule for network connections that implements stable KWTA networks. To widen the applications of WTA networks, a new class of WTA networks is proposed, and their efficient design methods are presented. We demonstrate the properties of the generalized class of WTA networks, through three application examples.  相似文献   
24.
本文研究了TiO2掺入对CaO稳定ZrO2(简称CaSZ-NiCr)金属陶瓷烧结特性的影响,测定了CaSZ-NiCr-TiO2金属陶瓷烧结样品的密度和显微硬度,结果表明,TiO2的掺入能提高CaSZ-NICr金属陶瓷的烧结密度和显微硬度,对CaSZ-NiCr金属陶瓷有助烧结作用.金相观察表明,TiO3的掺入改变了NiCr相在金属陶瓷中的形貌,说明了NiCr与CaSZ的浸润性有一定的改善.XRD和EPMA分析结果显示,TiO2偏聚在NiCr金属相中,不影响CaSZ的稳定性.  相似文献   
25.
The rapidly increasing popularity of mobile devices has changed the methods with which people access various network services and increased network traffic markedly. Over the past few decades, network traffic identification has been a research hotspot in the field of network management and security monitoring. However, as more network services use encryption technology, network traffic identification faces many challenges. Although classic machine learning methods can solve many problems that cannot be solved by port- and payload-based methods, manually extract features that are frequently updated is time-consuming and labor-intensive. Deep learning has good automatic feature learning capabilities and is an ideal method for network traffic identification, particularly encrypted traffic identification; Existing recognition methods based on deep learning primarily use supervised learning methods and rely on many labeled samples. However, in real scenarios, labeled samples are often difficult to obtain. This paper adjusts the structure of the auxiliary classification generation adversarial network (ACGAN) so that it can use unlabeled samples for training, and use the wasserstein distance instead of the original cross entropy as the loss function to achieve semisupervised learning. Experimental results show that the identification accuracy of ISCX and USTC data sets using the proposed method yields markedly better performance when the number of labeled samples is small compared to that of convolutional neural network (CNN) based classifier.  相似文献   
26.
The Journal of Supercomputing - In this paper, we propose a parallel source separation system designed to extract heart and lung sounds from single-channel mixtures. The proposed system is based on...  相似文献   
27.
The explosive growth of Chinese electronic market has made it possible for companies to better understand consumers?? opinion towards their products in a timely fashion through their online reviews. This study proposes a framework for extracting knowledge from online reviews through text mining and econometric analysis. Specifically, we extract product features, detect topics, and identify determinants of customer satisfaction. An experiment on the online reviews from a Chinese leading B2C (Business-to-Customer) website demonstrated the feasibility of the proposed method. We also present some findings about the characteristics of Chinese reviewers.  相似文献   
28.
Oblivious signature-based envelope (OSBE) schemes have demonstrated their potential applications in the protection of users privacy and rights. In an OSBE protocol, an encrypted message can only be decrypted by the receiver who holds a valid signature on a public message, while the sender (encrypter) does not know whether the receiver has the signature or not. Our major contributions in this work lie in the following aspects. We improve the notion of OSBE so that a valid credential holder cannot share his/her credential with other users (i.e., all-or-nothing non-transferability). We clarify the relationship between one-round OSBE and identity-based encryption (IBE) and show that one-round OSBE and semantically secure IBE against the adaptively chosen identity attack (IND-ID-CPA) are equivalent, if the signature in the OSBE scheme is existentially unforgeable against adaptively chosen message attacks. We propose an oblivious access control scheme to protect user privacy without the aid of any zero-knowledge proof. Finally, we also highlight some other novel applications of OSBE, such as attributed-based encryption.  相似文献   
29.
Industrial effluents usually include multicomponent organic solutes. The optimum pH for adsorption of a specific industrial effluent on activated carbon should be determined experimentally because, in general, more than one mechanism is involved. A series of experiments was conducted to establish the influence of the initial hydrogen ion concentration on carbon adsorption of organic solutes. For these studies, powdered activated carbon was used, and the water systems studied included both single component pure organic compounds as well as multicomponent organic wastes. Results indicate that the pH effect upon the effectiveness of carbon adsorption mainly depends upon the nature of the adsorbed substance. In general, the degree of ionisation is the controlling factor for adsorption of ionic organic solutes on activated carbon. Adsorption reaches a maximum at the point of least ionisation of the adsorbate. As the organic compounds become more complex (i.e. longer hydrocarbon chains, higher molecular weights, increased branching), the electrical adsorption forces between activated carbon and ionic organic solutes will govern. Anionic surfactants meet with decreased electronegative repulsive forces at low pH levels, which increase the effectiveness of carbon adsorption. However, the adsorption of a cationic surfactant is increased by an increase in the electronegative carbon surface at high pH levels. When ionic organic solutes become much more complex, like a polymer, the effects of both ionisation and electrical adsorption forces become less important. Instead, the adsorption rate will be controlled by the extent of hydrolysis caused by the pH adjustment. For non-ionic organic solutes, chemical reaction(s) between the adsorbate and the added chemical (acid or base) for pH adjustment is an important controlling factor. Again, hydrolysis is responsible for the breakdown of larger size molecules to smaller sizes. Then an increase in adsorption rate with decreasing molecular weight of adsorbate is expected.  相似文献   
30.
塑料在包装领域有着广泛的应用,其中聚酯(PET)性能优良,应用领域不断扩大。介绍了塑料包装不断通现的新技术,以及塑料包装环保问题的几点思路。  相似文献   
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