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111.
112.
Ryuji Miura Hideo Yamano Ryo Yamauchi Masahiko Katagiri Momoji Kubo Rajappan Vetrivel Akira Miyamoto 《Catalysis Today》1995,23(4):409-416
We have developed a new computer graphics (CG) code RYUGA for three-dimensional dynamic visualization of molecular dynamics (MD) results. The applicability of RYUGA for visualizing and analyzing the dynamics of atomic motions in various materials was demonstrated. RYUGA supports various functions, such as solid-modeling CG pictures (called the CPK model), CG animation of the MD results, Miller plane cutting of crystal structures, building graphs, etc., similar to other CG codes for MD simulation. In addition, RYUGA has a number of advantages as follows: (i) a perspective is employed for drawing CG pictures, (ii) three-dimensional trajectories of atoms can be constructed, (iii) an operator can travel inside the materials, (iv) graphic speed and animation speed are enhanced because of the specific algorithms, and (v) it works on any workstations, moreover even personal computers with a UNIX operating system and an X window system are available. 相似文献
113.
Tohma Y. Yamano H. Ohba M. Jacoby R. 《IEEE transactions on pattern analysis and machine intelligence》1991,17(5):483-489
Six ways to estimate parameters of the hypergeometric distribution are investigated, and their accuracies are examined comparatively. It is demonstrated that the least-squares sum method is the best one among those tried, and can be applied to real test/debug data for estimating the number of faults still resident in a program after test/debugging. By this method the estimation time can be reduced greatly 相似文献
114.
N Misawa S Yamano H Linden MR de Felipe M Lucas H Ikenaga G Sandmann 《Canadian Metallurgical Quarterly》1993,4(5):833-840
The possibility that extracellular matrix-cell surface interaction might lead to signalling was examined in human mononuclear cells. In mononuclear cells loaded with Indo-1 acetoxymethylester, collagen binding elicited a 2-3 fold increase in cytosolic free calcium concentration within seconds. Plasma fibronectin, serum albumin and heparin did not cause any significant change in intracellular calcium levels. Collagen I, collagen IV and glucosylated collagen I evoked an increase in intracellular Ca++ both in the presence and absence of extracellular calcium. However, in the presence of 2mM EDTA, the increase in cytosolic free calcium concentration caused by collagen I and collagen IV was partly abolished, suggesting the requirement of a cation-dependent interaction of collagen with mononuclear cells. Glucosylated collagen induced intracellular calcium mobilization even in the presence of EDTA suggesting a cation-independent interaction. These results indicate that collagen binding induces rapid mobilization of calcium in human mononuclear cells, apparently from intracellular sources. 相似文献
115.
Daichi Asakawa Masako Uemura Takanori Sakiyama Testuo Yamano 《Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment》2018,35(6):1116-1126
The development of a sensitive and accurate analytical method for monitoring aminoglycosides in food, environmental, and clinical samples is needed for many purposes. This study found that the responses of sodiated and protonated aminoglycosides in hydrophilic interaction chromatography with tandem mass spectrometry were enhanced upon addition of sodium acetate in methanol (5 mg L?1 at a flow rate of 0.2 mL min?1) as a post-column reagent. The sensitivities of sodiated spectinomycin, kanamycin, gentamicins, neomycin, and amikacin were significantly higher than those of the protonated molecules. Streptomycin and dihydrostreptomycin only formed protonated molecules, suggesting the preferential ionisation of the guanidine moieties in these aminoglycosides. The limits of quantification of these aminoglycosides were 0.19–2.5 ng mL?1. Notably, this is the first quantification of aminoglycosides that uses the sodiated molecules. The enhancement technique enables us to eliminate a concentration step from the clean-up process from food samples. We also proposed a rapid analytical method for residual aminoglycosides in milk and meat samples; validation showed good accuracy and precision of this method at the Japanese maximum residual limits of aminoglycosides (40–500 µg kg?1). The application of this method to contaminated bovine tissues revealed remarkably high residual levels of kanamycin. This technique will be useful for the sensitive detection of aminoglycosides not only in food, but also in environmental samples and human plasma. 相似文献
116.
Yamano Y. Tsurumizu T. 《Dielectrics and Electrical Insulation, IEEE Transactions on》1998,5(2):174-180
Surface PD (partial discharge) on an insulator from a TJ (triple junction) are reduced by recessing the TJ at the HV electrode. The insulators have an inner electrode connected to the ground potential. PD pulses whose magnitude is >10 pC are measured. The applied HV (50 Hz) is 1 to 1.5× higher than that at the initiation of the PD. The thickness of the insulator is in a range from 2 to 7.5 mm. For insulator thickness of 7.5 mm, the integrated magnitude and number of the PD pulses from the recessed TJ are reduced to ~20% and 50% of those from TJ without recess, respectively. The reduction in the pD by the recessed TJ is explained by the field conditions on the insulator near the TJ. It is considered that the reduction in the pD by the recessed TJ results mainly from the following three factors: high surface potential (Vs ) on the insulator, weak parallel component of electric field on the insulator surface, and strong normal component of the field on the surface. Propagation of the pD is restricted by these three factors. We have designed the improved configuration of recessed TJ in order to further emphasize these three factors. It is experimentally confirmed that the improved one reduces surface pD more efficiently than the recessed TJ before the improvement. At 7.5 mm insulator thickness, the integrated magnitude and number of pD pulses are reduced to ~5% and 15% of those for TJ without recess, respectively 相似文献
117.
N Yamano Y Matsushita Y Kamada S Fujishima M Arita 《Canadian Metallurgical Quarterly》1996,60(8):1320-1323
An enzyme that deacetylates N-acetylglucosamine to glucosamine from Vibrio cholerae non-O1 was purified to homogeneity by sequential procedures. The native enzyme had a molecular mass of 190,000 Da and was predicted to be composed of four identical subunits with molecular masses of 45,000 Da. The purified enzyme hydrolyzed N-acetylglucosamine, N-acetylglucosamine 6-phosphate, and N-acetylglucosamine 6-sulfate, but not chitin oligosaccharides, and N-acetylgalactosamine. The deacetylase activity was completely abolished by N-ethylmaleimide, p-chloromercuribenzoate, EDTA, and Cu2+. On the other hand, the activity was activated by Co2+. The amino-terminal amino acids of the purified enzyme were sequenced. Among the 22 N-terminal amino acid residues, 12 residues of Vibrio deacetylase were identical with that of Escherichia coli GlcNAc 6-phosphate deacetylase. 相似文献
118.
Evaluation of cleaning methods for residual orange extract on different cookware materials using ELISA with profilin allergen indicator 下载免费PDF全文
119.
Sadaji Ohkubo Kazuhiro Taniwaki Nagahiro Yamano 《Computer-Aided Civil and Infrastructure Engineering》1992,7(3):201-221
Abstract: A general-purpose, rigorous and efficient optimum design system for steel cable-stayed bridges is developed, in which not only can the cable anchor positions on the main girder and pylon, and the crosssectional dimensions of the member elements be dealt with as design variables, but also the pseudo-loads applied to the cables. A powerful two-stage optimum design method is proposed to determine the optimum values of design variables for the cost minimization problem under stress constraints. At the first-stage optimization process, the cable arrangement and sizing variables are optimized by using the approximate concept and dual method with mixed direct/inverse design variables. Then the optimum values of pseudoloads, which induce the optimum prestresses into the cables, and the optimum sizing variables are determined so as to minimize the total cost of the bridge further by utilizing the sensitivities with respect to the pseudo-loads and a modified linear programming algorithm. The rigorousness, eficiency and practical usefulness of the proposed optimum design system are demonstrated by giving numerical design examples and the investigations of the optimum solutions at various design conditions. The significances of dealing with cable anchor positions and pseudo-loads as design variables are also emphasized. 相似文献
120.
Tohru Suzuki Yoshiharu Tobita Hidemasa Yamano Satoru Kondo Koji Morita Tatsuya Matsumoto Ryo Akasaka Kenji Fukuda 《Nuclear Engineering and Design》2003,220(3):240-254
Complex phenomena such as phase transitions and heat transfers in multiphase, multicomponent flows were modeled in the fluid-dynamics portion of SIMMER-III, which was developed to appropriately assess core disruptive accidents (CDAs) in liquid–metal fast reactors (LMFRs). A new multicomponent vaporization/condensation (V/C) model was developed and introduced to SIMMER-III by the authors. In the present study, a new series of multi-bubble condensation experiments was performed to demonstrate that SIMMER-III with the present V/C model is practically applicable to multicomponent, multiphase flow systems with phase transition. In the experiments, bubble diameters and void fractions were quantified from visualization images using original image-processing techniques. Comparing SIMMER-III predictions with experimental data, it was confirmed that SIMMER-III with the proposed V/C model could suitably represent the effects of noncondensable components on the condensation process in multi-bubble systems. This work has improved the reliability of SIMMER-III with regard to multicomponent phase-transition phenomena. 相似文献