Design of CMIP-SNMPv2 Proxy Gateway for Network Management Interoperability

This paper describes the essential specificationand design of a CMIP-SNMPv2 application gateway fornetwork management integration and interoperability.Such a intermediate proxy software device allows management of Internet MIB-II objects throughISO/CCITT manager supporting CMIP protocol and CMISmanagement services. All the gateway functionality areexplained using dataflow diagrams. CMIP indication PDUs are transformed into functionallycorresponding SNMPv2 PDUs. Detailed service-mapping andname-mapping aspects consistent with the protocols,Internet MIB-II and the GDMO MIB are fully explored.SNMPv2 to CMIP inverse mapping is also explained indetail, followed by conclusions capturing the salientaspects of this design.     

Scattering characteristics of FSS comprised of L-shaped and one-turn helix shaped conductors for TE and TM excitation

The boundary value problem of doubly infinite periodic conductor arrays of L-shape and one-turn helix shape frequency selective surfaces (FSSs) backed by dielectric substrate are investigated by using modal expansion method. The moment method is employed by expressing the current induced on the metallic surfaces in terms of Piecewise Sinusoidal (PWS) functions. The variation of the reflection and transmission coefficients versus frequency for dielectric backed FSS is investigated for both transverse electric and transverse magnetic wave excitations at normal incidence. Reflection coefficients of dielectric backed FSS at normal and oblique incidence are plotted against frequency. The correctness of the algorithm is ensured by comparing the numerical results with the experimental results in the literature for an FSS composed of strips and proved to be as good. Tel.: +90-342-3601200 ext: 2131     

Minimization of warpage and sink index in injection-molded thermoplastic parts using Taguchi optimization method

The objective of this paper consist of minimization of the warpage and sink index in terms of process parameters of the plastic parts have different rib cross-section types, and rib layout angle using Taguchi optimization method. Considering the process parameters such as mold temperature, melt temperature, packing pressure, in addition to rib cross-section types, and rib layout angle, a series of mold analyses are performed to exploite the warpage and sink index data. The polymeric materials were selected PC/ABS, POM, and PA66. Taguchi optimization method was used by exploiting mold analyses based on three level factorial design. Orthogonal arrays of Taguchi, the signal-to-noise (S/N) ratio, the analysis of variance (ANOVA) are utilized to find the optimal levels and the effect of process parameters on warpage and sink index. Confirmation analysis test with the optimal levels of process parameters are carried out in order to demonstrate the goodness of Taguchi method. From this, it can be concluded that Taguchi method is very suitable to solve the quality problem occurring the injection-molded thermoplastic parts.     

The estimation of NMVOC emissions from an urban-scale wastewater treatment plant

The emissions of 19 different non-methane volatile organic compounds (NMVOCs) from the sewage treatment plant of the province of Eski?ehir in Turkey were estimated. The estimations were based on the modified surface-renewal model suggested by EPA. The estimated total annual amounts of the pollutants emitted (from the plant's primary and secondary clarifier units and their weirs, as well as the aerated biological treatment unit) varied between a range of 0.00024 t (1,3-dichlorobenzene) and 0.1646 t (tetrachloroethylene). The corresponding flux data ranged from 9.98 x 10(-10)g cm(-2) h(-1) (1,3-dichlorobenzene) to 8450 x 10(-10)g cm(-2) h(-1) (tetrachloroethylene). Resulting total hourly NMVOC emission rate (0.041 kg h(-1)) was found not to exceed the current national standards. This work may be considered as a regional background for a possible contribution to the national and international emission inventory study on NMVOCs.     

Screening for diabetic retinopathy using computer based image analysis and statistical classification

Diabetic retinopathy is one of the most common causes of blindness in Europe. However, efficient therapies do exist. An accurate and early diagnosis and correct application of treatment can prevent blindness in more than 50% of all cases. Digital imaging is becoming available as a means of screening for diabetic retinopathy. As well as providing a high quality permanent record of the retinal appearance, which can be used for monitoring of progression or response to treatment, and which can be reviewed by an ophthalmologist, digital images have the potential to be processed by automatic analysis systems. We have described the preliminary development of a tool to provide automatic analysis of digital images taken as part of routine monitoring of diabetic retinopathy in our clinic. Various statistical classifiers, a Bayesian, a Mahalanobis, and a KNN classifier were tested. The system was tested on 134 retinal images. The Mahalanobis classifier had the best results: microaneurysms, haemorrhages, exudates, and cotton wool spots were detected with a sensitivity of 69, 83, 99, and 80%, respectively.     

A new in vitro/in vivo kinetic correlation method for nitrofurantoin matrix tablet formulations

The kinetic distributions of in vitro percentage release and in vivo percentage urinary excretion rates of nitrofurantoin from matrix tablets were plotted using a kinetic program. In vitro release rates were determined using the USP paddle and half-change methods. Urinary excretion curves of the drug were characterized by means of the statistical moments. The individual linear correlations between each in vitro and in vivo kinetic distribution were established, and regression equations were calculated. The application results of the best correlations obtained were evaluated according to in vivo results. A reversed kinetic procedure was applied for transformation of the correlated kinetic values to the drug percentage release rates. The modified Langenbucher kinetic showed excellent linear correlation (r = .9985). The method that is proposed in this study, the kinetic correlation program, is simple, independent of time, and suggests that it is possible to use kinetic distributions in the in vitro/in vivo correlation. This study also suggests using kinetic correlation to investigate the suitability of the in vitro dissolution methods with the in vivo drug dissolution.     

Energy recovery from hydrogen combustion at elevated pressures

Hydrogen is assumed as one of the most environmentally benign fuels. By the combustion of hydrogen enormous amount of H₂O; and therefore, latent heat is produced. Because, there is not so much need to heat at low temperatures, methods are needed to recover latent heat at higher temperatures. One of the methods to upgrade the latent heat at higher temperatures is the method of combustion at elevated pressures. Increasing the pressure of the exhaust gas makes it possible to recover latent heat and higher extra exergy output from the system. In this work, both latent and sensible heat recoveries at elevated pressures are investigated using environmentally friendly fuel hydrogen. It is shown that coefficient of performance (COP) and exergy efficiency (${\eta }_{ex}$) is very satisfactory even at high pressures.     

Ionising Radiation Promotes Invasive Potential of Breast Cancer Cells: The Role of Exosomes in the Process

Along with the cells that are exposed to radiation, non-irradiated cells can unveil radiation effects as a result of intercellular communication, which are collectively defined as radiation induced bystander effects (RIBE). Exosome-mediated signalling is one of the core mechanisms responsible for multidirectional communication of tumor cells and their associated microenvironment, which may result in enhancement of malignant tumor phenotypes. Recent studies show that exosomes and exosome-mediated signalling also play a dynamic role in RIBE in cancer cell lines, many of which focused on altered exosome cargo or their effects on DNA damage. However, there is a lack of knowledge regarding how these changes in exosome cargo are reflected in other functional characteristics of cancer cells from the aspects of invasiveness and metastasis. Therefore, in the current study, we aimed to investigate exosome-mediated bystander effects of 2 Gy X-ray therapeutic dose of ionizing radiation on the invasive potential of MCF-7 breast cancer cells in vitro via assessing Matrigel invasion potential, epithelial mesenchymal transition (EMT) characteristics and the extent of glycosylation, as well as underlying plausible molecular mechanisms. The findings show that exosomes derived from irradiated MCF-7 cells enhance invasiveness of bystander MCF-7 cells, possibly through altered miRNA and protein content carried in exosomes.     

The effect of Dy3+ doping on the thermoluminescence properties of Ba2SiO4

The thermoluminescence (TL) properties of barium silicate phosphor, Ba₂SiO₄:%3Dy³⁺ synthesized by using hydrothermal method were investigated and presented in detail. The crystallographic structure of Ba₂SiO₄:%3Dy³⁺ was determined by conventional x-ray diffraction technique and the results showed that the sample was grown in orthorhombic phase with Pmcn (62) space group (PDF: 01-077-0150). The excitation spectra of Ba₂SiO₄:Dy³⁺ were measured in the wavelength range of 220-400 nm and the spectra showed that there were several excitation bands in the sample. The CIE chromaticity coordinates were also calculated from emission spectra for Dy³⁺-doped Ba₂SiO₄. In order to calculate the kinetic parameters of the sample the additive dose, peak shape and computerized glow curve deconvolution methods were used. It was found that Ba₂SiO₄:Dy³⁺ was composed of five general order TL glow peaks. The fading characteristics of the sample were also studied over a period time. At the end of the planned storage times, the normalized TL peak area of Ba₂SiO₄:Dy³⁺ reduced 60% of its original value.