STEP-NC compliant process planning of additive manufacturing: remanufacturing

Additive manufacturing is becoming one of the key methods for reproducing repair sections in remanufacturing processes. The major advantage of using additive processes is to minimize production time and waste. However, the surface quality and shape accuracy are usually insufficient for the final product because the approximated representation format causes the accumulation of the error during the geometric operations of the process planning. This limitation is a barrier to utilize additive processes as finishing processes, such as general metal cutting. There is need to improve the final quality of parts obtained with additive manufacturing. In this paper, STEP-based numerical control (STEP-NC)-based process planning is applied to the additive manufacturing. ISO 14649 (STEP-NC) describes part programs with geometric data directly and also contains the information necessary for the intelligent process planning. This paper proposes the STEP-NC-based representation method of additive manufacturing and the series of geometric reasoning to automate the derivation of the repair section. The proposed representation has the benefits to provide a high accuracy for the final surface and to describe multiple materials. Topological data maintain low error during the series of process planning through the CAD-CAM-CNC chain. The proposed platform supports consideration of the process tolerance and comparison of the selected plan with alternative processes. In order to show the practical advantages, an analysis of the remanufacturing process is carried out. The case study of remanufacturing a pocket part is presented in order to validate the proposed process plan. The result of the case study shows the improvement in terms of automatic process planning and surface quality accuracy.     

Growth of hydroxyapatite on physiologically clotted fibrin capped gold nanoparticles

The growth of hydroxyapatite (HAp) on physiologically clotted fibrin (PCF)-gold nanoparticles is presented for the first time by employing a wet precipitation method. Fourier transform infrared (FTIR) spectroscopy confirmed the characteristic functionalities of PCF and HAp in the PCF-Au-HAp nanocomposite. Scanning electron microscopy (SEM) images have shown cuboidal nanostructures having a size in the range of 70-300?nm of HAp, whereas 2-50?nm sized particles were visualized in high-resolution transmission electron microscopy (TEM). Energy-dispersive x-ray (EDX) and x-ray diffraction (XRD) studies have confirmed the presence of HAp. These results show that gold nanoparticles with PCF acted as a matrix for the growth of HAp, and that PCF-Au-HAp nanocomposite is expected to have better osteoinductive properties.     

Effect of SBS and HDPH polymer on rheological properties of asphalt

The present work discusses the combined effect of High Density Polyethylene Homo polymer and Styrene-Butadiene-Styrene on properties of Viscosity Grade 30 asphalt commonly used in India. Six blends of binders were prepared using varying percentages of both polymers and were evaluated for rheological properties. Use of both polymers leads to higher viscosity, while blending with HDPH polymer only leads to marginal increase in viscosity when compared to unmodified binder. Comparison of dynamic modulus and phase angle master curves indicated, significant differences were found among master curves obtained with different aging conditions when compared to unaged condition especially at lower reduced frequencies.     

Radiosensitizer Effect of β-Apopicropodophyllin against Colorectal Cancer via Induction of Reactive Oxygen Species and Apoptosis

β-apopicropodophyllin (APP), a derivative of podophyllotoxin (PPT), has been identified as a potential anti-cancer drug. This study tested whether APP acts as an anti-cancer drug and can sensitize colorectal cancer (CRC) cells to radiation treatment. APP exerted an anti-cancer effect against the CRC cell lines HCT116, DLD-1, SW480, and COLO320DM, with IC50 values of 7.88 nM, 8.22 nM, 9.84 nM, and 7.757 nM, respectively, for the induction of DNA damage. Clonogenic and cell counting assays indicated that the combined treatment of APP and γ-ionizing radiation (IR) showed greater retardation of cell growth than either treatment alone, suggesting that APP sensitized CRC cells to IR. Annexin V–propidium iodide (PI) assays and immunoblot analysis showed that the combined treatment of APP and IR increased apoptosis in CRC cells compared with either APP or IR alone. Results obtained from the xenograft experiments also indicated that the combination of APP and IR enhanced apoptosis in the in vivo animal model. Apoptosis induction by the combined treatment of APP and IR resulted from reactive oxygen species (ROS). Inhibition of ROS by N-acetylcysteine (NAC) restored cell viability and decreased the induction of apoptosis by APP and IR in CRC cells. Taken together, these results indicate that a combined treatment of APP and IR might promote apoptosis by inducing ROS in CRC cells.     

Morphological core/shell structure and dispersion stability of water-dispersible copolyester graft polymerized with acrylic acid and ethyl acrylate

Anionic water-dispersible copolyester was prepared by the polycondensation of dimethyl isophathalate (DMI)/5-sodium sulfo dimethyl isophathalate (DMS) with ethylene glycol (EG)/ diethylene glycol (DEG) to synthesize water-dispersible copolyester-g-AA/EAs by chemical method. In the case of graft polymerization of AA/EA onto DMI/DMS/EG/DEG copolyester does not. This is a result of the core/shell structure that was ascertained by the graft yield and the zeta potential of copolyester-g-AA/EAs. It appears that grafted AA/EA exists at the surface of copolyester-g-AA/EA particles, and the backbone polymer, i.e., DMI/DMS/EG/DEG copolyester, exists in the inner phase of the copolyester, -g-AA/EA particles. The complete solubility of copolyester-g-AA/EAs in 1N NaOH aqueous solution seems to come mainly from the electrostatic repulsion between  COOs that are present at the surface of copolyester-g-AA/EA particles due to AA grafting and  OHs that are present at the dispersion medium due to NaOH decomposition and which cause the hydrolytic breakage and consequently the coagulation of copolyesters in alkaline medium. © 1996 John Wiley & Sons, Inc.     

Analysis of Collaborative Brain Computer Interface (BCI) Based Personalized GUI for Differently Abled

Brain-Computer Interfaces (BCI) use Electroencephalography (EEG) signals recorded from the brain scalp, which enable a communication between the human and the outside world. The present study helps the patients who are people locked-in to manage their needs such as accessing of web url’s, sending/receiving sms to/from mobile device, personalized music player, personalized movie player, wheelchair control and home appliances control. In the proposed system, the user needs are designed as a button in the form of a matrix, in which the main panel of rows and columns button is flashed in 3 sec intervals. Subjects were asked to choose the desired task/need from the main panel of the GUI by blinking their eyes twice. The double eye blink signals extracted by using the bio-sensor of NeuroSky’s mind wave device with portable EEG sensors are used as the command signal. Each task is designed and implemented using a Matlab tool. The developed Personalized GUI application collaborated with the EEG device accesses the user’s need. Once the system identifies the desired option through the input control signal, the appropriate algorithm is called and performed. The users can also locate the next required option within the matrix. Therefore, users can easily navigate through the GUI Model. A list of personalized music, movies, books and web URL’s are preloaded in the database. Hence, it could be suitable to assist disabled people to improve their quality of life. Analysis of variance (ANOVA) is also carried out to find out the significant signals influencing a user’s need in order to improve the motion characteristics of the brain computer interface based system.     

Development of non-perfluorinated hybrid materials for single-cell proton exchange membrane fuel cells

Development of low temperature fuel cells that operate under 100 °C are needed to reduce the costs, to design a class of hybrid membranes and to construct various structures of membrane-electrode-assembles (MEAs) for proton exchange membrane fuel cells (PEMFC). In this work, PVA/PMA/SiO₂ hybrid composite membranes were synthesized and their conductivities were determined by impedance measurements. We found a maximum conductivity value of 4.2 × 10⁻³ S/cm at 80 °C and 100% relative humidity (RH). A fuel cell test evaluation for various MEAs was conducted by the potentiodynamic analysis and the current density values were determined from the current–voltage (I–V) curves. A maximum current density of 635 mA/cm² was obtained at 80 °C and 100% RH. To the best of our knowledge, this is the first time that a high current density of PVA-based electrolytes for PEMFCs operating at low temperature is reported. The structural characters were examined using of XRD and FTIR methods, and thermal properties were studied using DSC and TGA techniques and the results were discussed (cf. supplementation). The present study revealed that the single cell performance depends mainly on the temperature, relative humidity and chemical compositions of the membranes.