On solving constrained optimization problems with neural networks:a penalty method approach

Deals with the use of neural networks to solve linear and nonlinear programming problems. The dynamics of these networks are analyzed. In particular, the dynamics of the canonical nonlinear programming circuit are analyzed. The circuit is shown to be a gradient system that seeks to minimize an unconstrained energy function that can be viewed as a penalty method approximation of the original problem. Next, the implementations that correspond to the dynamical canonical nonlinear programming circuit are examined. It is shown that the energy function that the system seeks to minimize is different than that of the canonical circuit, due to the saturation limits of op-amps in the circuit. It is also noted that this difference can cause the circuit to converge to a different state than the dynamical canonical circuit. To remedy this problem, a new circuit implementation is proposed.     

Intussusception caused by a carcinoma of the cecum during pregnancy: report of a case and review of the literature

Respiratory infections are the most common infection in children. They differ remarkably according to age, bacteria and viruses. Therefore a careful history of outbreak, age, former infections, involvement of surroundings, symptoms, etc are essential. The present study included 50 children, aged between 0.3 and 12 yrs, all treated ambulatorily. 21 received brodimoprim (B) and 29 erythromycin (E). Indications were: tonsillitis, bronchitis, otitis media, sinusitis and scarlet fever. Dosages were: B was given 10 mg/kg body weight (b.w.) initially followed by 5 mg/kg b.w., once-a-day. The duration of treatment varied between 4 and 14 days (mean 8.3 days). E was given 30.50 mg/kg b.w. 3 times per day; duration 4 to 14 days (mean 8.6 days). Overall results were: in group B:12 cures, 5 improvements, 3 failures; 1 not assessable. In group E: 20 cures, 8 improvements, 1 failure. Side effects: in group B: vomiting (1), skin reaction (2), discontinuation (2); in group E: skin reaction (1), diarrhea (5), diarrhea+vomiting (1); discontinuation (2). The differences in efficacy and tolerability in the two groups are not statistically significant. The improved compliance with a single versus t.i.d. dosages has to be taken into account.     

MEASUREMENT OF THE SPECIFIC SURFACE AREA OF POWDERS BY THIN LAYER WICKING

The specific surface areas (A) of different clay mineral powders were measured by both the BET method and by thin layer wicking. The values of A for the BET and the wicking experiments coincided within a few percent. Thus, the simple and inexpensive thin layer wicking approach may well suffice to obtain reliable specific surface area values for most powders. From the wicking data it is also possible to obtain a rough estimate of the average particle size.     

Use of gas plasmas to increase breakdown strengths in polycarbonatefilm/foil capacitors

It is shown that the electrical breakdown voltages of polycarbonate film/metal foil capacitors can be increased. This can be achieved by briefly exposing the metal foil in these spirally wound film foil sections to a low-pressure, low-temperature gas plasma. Exposure of tin/lead foil to a 96% CF₄/4% O₂ gas plasma for four min, for example, produced >500% increase in breakdown voltage of sealed polycarbonate capacitors     

Langzeitiges Kriechrißverhalten kennzeichnender Kraftwerksstähle

Long Term Creep Crack Behaviour of Typical Power Plant Steels The creep crack behaviour of the steels was investigated in a wide loading range up to a test duration of 40 000 h and down to a creep crack growth rate of 2 · 10^?5 mm/h with specimens of different shape and size. For steels of type l%Cr-l%Mo-0.6%Ni-0.3%V, 1%Cr-0.9%Mo-0.7%Ni-03.%V, 12%Cr-1%Mo-0.3%V-0.22%C and 12%Cr-l%Mo-0.3%V-0.20%C tested at 550°C, the creep crack growth rate could be described by the parameter C₂* with significantly smaller scatter bands than by the parameter C₁* or the stress intensity factor K_I. For steel 12%Cr-2%Ni-1%Mo tested at 450°C, parameter K_I leads to the smallest scatter band. The creep crack initiation can be described in a two-criteria diagram based on nominal stress and stress intensity factor. However the method is assumed to be over-conservative in case of increasing specimen size. As a result of several aperiodic creep fatigue crack tests, precracking under fatigue conditions gave a weak increase of the creep crack growth rate whereas by precracking under creep conditions the fatigue crack rate was strongly decreased.     

Peritoneal healing after fibrin glue application: a comparative study in a rat model

The influence of fibrin glue on adhesion formation and peritoneal healing is evaluated in a prospective, randomized, controlled study. In all, 20 Wistar rats underwent microsurgical suturing of two silicone sheets, one covered with a fibrin glue barrier, to the anterior peritoneum. Each animal thus served as its own control. After 10 days, adhesions and peritoneal healing were evaluated by a blinded observer through a second-look laparotomy. Adhesions were scored using a modification of the classification of Diamond. Tissue around the silicone sheet was examined histologically and by scanning electron microscopy to evaluate the inflammatory reaction and peritoneal healing (ingrowth of blood vessels and quality of peritoneal cells). Adhesion scores for treated and control sides were (mean +/- SD) 2.89 +/- 4.68 and 6.79 +/- 9.09 (P = 0.181) respectively, and the percentage of the sheet covered by peritoneum was 26.25 +/- 31.50 and 29.21 +/- 40.21 (P = 0.226) respectively. Using the paired Wilcoxon rank test, the P values for the ingrowth of blood vessels and peritoneal healing evaluated by histology and scanning electron microscopy were 0.842, 0.692 and 0.695 respectively. We conclude that although the mean adhesion score was reduced by > 50% by fibrin glue, there is no statistically significant difference concerning adhesion formation or peritoneal healing with the use of fibrin glue.     

The effects of retinol on in vitro immunoglobulin synthesis by cord blood and adult peripheral blood mononuclear cells

In this study we examined the effects of retinol (ROH), a metabolic precursor of retinoic acid (RA), on Staphylococcus aureus Cowan I (SAC)-induced immunoglobulin synthesis of cord blood mononuclear cells (CBMC) and adult peripheral blood mononuclear cells (PBMC). ROH augmented SAC-induced IgM synthesis of CBMC by 5.9 +/- 1.5-fold (n = 7, mean +/- s.d.), and IgG synthesis of adult PBMC by 16.3 +/- 5.1-fold (n = 3) at optimal concentrations of 10(-6) M and 10(-11) M, respectively. No augmenting effects could be demonstrated for the other immunoglobulin isotypes. Time-course studies showed that the synthesis of IgM by CBMC was accelerated with detectable immunoglobulin in supernatant fluids starting on day 3. ROH augmented immunoglobulin synthesis of CBMC stimulated by Epstein-Barr virus (EBV), a T cell-independent polyclonal activator, and of EBV-transformed B cell clones (2.5 +/- 0.2 and 4.1 +/- 1.5-fold increase, respectively), which suggests that ROH can act directly on B cells to enhance immunoglobulin synthesis. In contrast, when ROH was preincubated with cord blood T cells, washed and added to the B cell-enriched fraction with SAC, no increase (0.9-1.8-fold) in IgM synthesis was obtained. Thus, the principal mechanism(s) by which ROH augments immunoglobulin synthesis is by acting on B cells. This is in contrast to the immunoglobulin-enhancing effects of RA which is mediated by T cells, or T cell products, e.g. cytokine. Our studies suggest that RA and ROH may have different pathways of immunoglobulin-enhancing effects, perhaps mediated by different retinoid binding proteins resulting in gene activation and immunoglobulin synthesis.     

Hierarchical intelligent control with flexible AC transmission systems application

A novel hierarchical intelligent controller configuration is proposed using an artificial neural network as a control-mode classifier in the supervisory level and a set of pre-designed controllers in the lower level. Controller outputs are modified nonlinearly by the classifying signals in a structure resembling one artificial neuron with adaptively changed weights. The lower-level local controllers are implemented using neural networks. An illustrative example of this approach is based on the transient stabilization of a single-machine infinite-bus system studied in Flexible AC Transmission Systems (FACTS) research.     

Our gynecologic heritage. Robert von Olshausen (1835-1915), pioneer in surgical gynecology. 5th contribution on the history of the Berlin Society of Obstetrics and Gynecology

Robert von Olshausen was an outstanding German gynecologist at the turn of the century and a pioneer of operative gynaecology. His fields of excellency were ovarotomy, the problems of asepsis, carcinoma therapy and the development of obstetrics in general. Under his chairmansship, the Berlin Department of Obstetrics and Gynecology (Universit?ts-Frauenklinik) became the leading Clinic in Germany. For many years Olshausen was the chairman of the Berlin Society of Obstetrics and Gynecology, since 1894 as honorary chairman. The present paper is a biography of Robert von Olshausen, showing his importance for the development of the modern gynaecology in Berlin and Germany.