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161.
对院基寺水库运行过程中出现的坝基渗漏现象进行了全面的描述,结合坝址工程地质和水文地质条件、施工情况及坝体结构,系统地分析了产生渗漏的原因及渗漏途径,并提出了防渗帷幕灌浆处理方案。灌浆试验、现场施工质量检查及实际观测成果证实,工程处理措施取得了良好的效果。 相似文献
162.
Xu Baowen Zhang Weifeng 《电子科学学刊(英文版)》2002,19(4)
The users' interest can be mined from the web cache and can be used widely. The interest can be specialized by the two-tuple (term, weight) in the simple interest model, in which the association relations are not mined, and then the interest cannot be associated in expressing the users' interest. Based on analyzing the WWW cache model, this letter brings forward a two-dimensional interest model and gives the interrelated methods on how to store the two-dimensional interest model effectively. 相似文献
163.
The kinetics of substrate removal by the liver and the resulting nonlinear changes in unbound fraction along the flow path at varying input drug concentrations were examined by a model simulation study. Specifically, we varied the binding association constant, KA, and the Michaelis-Menten constants (Km and Vmax) to examine the steady state drug removal (expressed as hepatic extraction ratio E) and changes in drug binding for (i) unienzyme systems and (ii) simple, parallel metabolic pathways; zonal metabolic heterogeneity was also added as a variable. At low KA, E declined with increasing input drug concentration, due primarily to saturation of enzymes; only small differences in binding were present across the liver. At high KA, a parabolic profile for E with concentration was observed; changes in unbound fraction between the inlet and the outlet of the liver followed in parallel fashion. Protein binding was the rate-determining step at low input drug concentrations, whereas enzyme saturation was the rate-controlling factor at high input drug concentration. Heterogeneous enzymic distribution modulated changes in unbound fraction within the liver and at the outlet. Despite marked changes in unbound fraction occurring within the liver for different enzymic distributions, the overall transhepatic differences were relatively small. We then investigated the logarithmic average unbound concentration and the length averaged concentration as estimates of substrate concentration in liver in the presence of nonlinear drug binding. Fitting of simulated data, with and without assigned random error (10%), to the Michaelis-Menten equation was performed; fitting was repeated for simulated data obtained with presence of a specific inhibitor of the high-affinity, anteriorly distributed pathway. Results were similar for both concentration terms: accurate estimates were obtained for anterior, high affinity pathways; an overestimation of parameters was observed for the lower affinity posteriorly distributed pathways. Improved estimations were found for posteriorly distributed pathways upon inhibition with specific inhibitors; with added random error, however, the improvement was much decreased. We applied the method for fitting of several sets of metabolic data obtained from rat liver perfusion studies performed with salicylamide (SAM) (i) without and (ii) with the presence of 2,6-dichloro-4-nitrophenol (DCNP), a SAM sulfation inhibitor. The fitted results showed that SAM sulfation was a high-affinity high-capacity pathway; SAM glucuronidation was of lower affinity but comparable capacity as the sulfation pathway, whereas SAM hydroxylation was of lower affinity and lower capacity. 相似文献
164.
One month following the Great Hanshin Earthquake of January 17, 1995, we conducted a survey of 173 hospitals in Aichi Prefecture to pinpoint problems related to their actual disaster-readiness and the medical backup systems in place to deal with such disasters. This study revealed that staff at 50% of the surveyed hospitals could reach the hospital within an hour, but that communication is almost entirely dependent on phone lines, suggesting that cordless/portable/mobile phones, radio systems, Internet, communications satellites and the like should be studied in the days to come for possible use as effective communication alternatives in times of disaster. Whereas 92% of the surveyed hospitals had manuals dealing with fire outbreaks, other areas were less well represented. For example, only 36.9% of surveyed hospitals had manuals for earthquakes, 31.7% had manuals for power outages and 14.2% had manuals to deal with flooding and water disasters. New manuals must be developed incorporating the key points garnered from experience (especially Hanshin) and be ready for use immediately. It is the time for each hospital to seriously rethink the measures it should take to deal with disasters. 相似文献
165.
Boole函数的线性可分性是前向人工神经网络理论中的一个比较困难的问题之一。目前仅对变量数n≤7的某些问题给予讨论。当n≥8时,尚无判别Boole函数线性可分的一般准则,更无线性可分Boole函数的计数公式。基于此,本文详细地研究了与Boole函数线性可分性有关的n-维超立方体的基本理论,包括n-维超立方体的基本性质、超立方体中的平行线、子超立方体的计数等,并给出了构造n-维超立方体图的一种新方法。 相似文献
166.
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169.
无线局域网安全问题研究 总被引:10,自引:0,他引:10
为了提供相当于有线局域网的数据安全,IEEE802.11定义了有线等价保密(WEP)协议。然而,最近的研究发现WEP存在严重的缺陷。介绍了无线局域网存在的安全隐患,分析了WEP的结构以及WEP协议的缺陷以及可能遭受的攻击,并探讨了改进方案。 相似文献
170.