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排序方式: 共有321条查询结果,搜索用时 31 毫秒
31.
K Hosokawa S Yoshitatsu M Kakibuchi S Nishimoto M Higashiyama K Yoshikawa 《Canadian Metallurgical Quarterly》1998,102(2):448-449
We report a case of identical twins with recessive dystrophic epidermolysis bullosa, who developed squamous cell carcinoma in the hand at the latter half of their third decade. To our knowledge, this is the first case of manifestation of squamous cell carcinoma in identical twins and may contribute to the understanding of oncogenesis in such patients. 相似文献
32.
When methyl mercury chloride was administered orally the amount of mercury excretion with feces of germfree mice was noticeably lower than that of the control mice. Germfree mice excreted 24 percent of the administered mercury within 10 days of administration while the control mice excreted 46 percent. Mercury retention in the organs of germfree mice was slightly higher than in the control mice. These results suggest that the existence of microorganisms in animal intestines are concerned with mercury excretion in the animal body. 相似文献
33.
Particle-initiated breakdown characteristics in SF6 gas are investigated. Breakdown voltages are greatly influenced by particle diameter especially for AC voltages, and for very fine metallic wire particles are much higher than those for moderately thick ones. The breakdown stress of a gas gap is obtained as a function of particle length and can be estimated fairly well by assuming a corona stabilizing zone. For a spacer, the electric stress which is parallel to its surface dominates surface breakdowns and the relation between the stress and particle length is experimentally determined. In order to increase breakdown voltages, the effects of both the dielectric coating on a high-voltage electrode and spacer shape are examined. Finally, the effectiveness of the dielectric coating on a grounded electrode is demonstrated to prevent particle levitation. 相似文献
34.
T Yamashita K Hayakawa M Hosokawa T Kodama N Inoue K Tomita H Kobayashi 《Canadian Metallurgical Quarterly》1982,73(2):222-228
The incidence of tumor metastases was studied in WKA/Hok rats after cryosurgery and surgical excision of primary tumors. When rats with syngeneic fibrosarcoma, KMT-17, were treated by cryosurgery 5 days after transplantation of the tumor, 15 out of 31 rats (48.4%) died with tumor metastases. In contrast only 4 out of 34 (11.8%) died with tumor metastasis after surgical excision. Because tumor cells either in the regional lymph nodes or in the peripheral blood were already detectable in about half of the rats treated by either cryosurgery or surgical excision, mechanical and physical control of enhanced metastasis by cryosurgery is ruled out. The development of anti-tumor immunity was delayed in the rats treated by cryosurgery as compared with that in rats treated by surgical excision. This was investigated by means of Winn's assay. A marked reduction of tumor metastasis was seen after the surgical removal of cryonecrotized tumor tissue, while implantations of cryonecrotized tumor tissue into the rats treated by surgical excision resulted in an increment of metastasis. The mechanism of the enhanced metastasis observed in this experimental investigation is discussed from an immunological point of view. 相似文献
35.
36.
H. Sawada T. Sasaki F. Hosokawa S. Yuasa M. Terao M. Kawazoe T. Nakamichi T. Kaneyama Y. Kondo K. Kimoto K. Suenaga 《Ultramicroscopy》2010
We developed a new electron optical system with three dodecapoles to compensate for spherical aberration and six-fold astigmatism, which generally remains in a two-hexapole type corrector. In this study, we applied the corrector for image-forming system in transmission electron microscope. Compensation for higher-order aberration was demonstrated through a diffractogram tableau using a triple three-fold astigmatism field system, which was then compared with a double hexapole field system. Using this electron optical system, six-fold astigmatism was measured to be less than 0.1 mm at an acceleration voltage of 60 kV, showing that the system successfully compensated for six-fold astigmatism. 相似文献
37.
Saburo Hosokawa Yukihiro Hayashi Seiichiro Imamura Kenji Wada Masashi Inoue 《Catalysis Letters》2009,129(3-4):394-399
Ceria colloidal particles with a mean crystallite size of 2 nm were synthesized by a solvothermal reaction. The Ru/CeO2 catalyst prepared from the CeO2 colloids exhibited higher activity than the catalyst prepared from Ce(NO3)3. Temperature-programmed reduction analysis indicated that the reduction of surface Ce4+ was accelerated by highly dispersed Ru species on the CeO2 particles and occurred at low temperatures. The single component CeO2 sample prepared by the coagulation of the CeO2 colloid was more easily reduced and re-oxidized than the CeO2 sample prepared by the precipitation method from Ce(NO3)3. The higher activity of Ru/CeO2 prepared from the CeO2 colloids came from the inherent nature of the CeO2 support itself. 相似文献
38.
Yokohira M Yamakawa K Saoo K Matsuda Y Hosokawa K Hashimoto N Kuno T Imaida K 《Journal of food science》2008,73(7):C561-C568
To clarify the effects of purple corn color, enzymatically modified isoquercitrin (EMIQ), and isoquercitrin (IQ), registered as natural food additives in Japan, on liver carcinogenesis in vivo, a medium-term bioassay was employed. A total of 100 male F344 rats were divided into 5 groups; groups 1 to 4 were given a single intraperitoneal injection of diethylnitrosamine (200 mg/kg b.w.) on day 1. From weeks 2 to 8, they were administered basal diet purple corn color, EMIQ, or IQ as containing test chemicals at doses of 1.0% (groups 1 and 5), 0.1% (group 2), 0.01% (group 3), or 0% (group 4) (experiments 1, 4, and 5). All rats were subjected to two-thirds partial hepatectomy at week 3 and were sacrificed at week 8. Purple corn color exerted no significant modifying effects on GST-P positive foci, preneoplastic foci, development in the liver. However, serum of rats treated with purple corn color provided evidence of antioxidant power significantly by potential antioxidant (PAO) test in vivo (experiment 2). And microarray analyses showed purple corn color to induce RNA expression such as P450 (cytochrome) oxidoreductase, phosphatidylinositol 3-kinase, and phospholipase A2 (experiment 3). Higher doses of EMIQ or IQ with strong antioxidant power in vivo by PAO test treated groups were correlated with smaller numbers of GST-P positive foci, with Spearman's rank correlation coefficients of P= 0.002 and P= 0.049, respectively (experiments 4 and 5). Therefore, the tested food additives may be effective as antioxidants in vivo and have chemopreventive potential against liver preneoplastic lesion development. 相似文献
39.
Water activity-adjusted enzymatic partial hydrolysis of phospholipids to concentrate polyunsaturated fatty acids 总被引:2,自引:0,他引:2
Masayo Ono Masashi Hosokawa Yoshikazu Inoue Koretaro Takahashi 《Journal of the American Oil Chemists' Society》1997,74(11):1415-1417
Selective partial hydrolyses of egg yolk phospholipid and squid skin phospholipid were carried out. By keeping the water activity
(a
w) of Lipozyme IM at an intermediate level, it was easy to concentrate docosahexaenoic acid (DHA). It was also possible to
concentrate both DHA and arachidonic acid (AA) simultaneously to a certain level under this a
w range. However, it was impossible to concentrate AA alone when DHA was present. Though there is a limitation in concentrating
AA exclusively, the proposed a
w-adjusted hydrolytic reaction is a promising way for preparing phospholipids rich in DHA. 相似文献
40.
Masashi Hosokawa Koretaro Takahashi Yuji Kikuchi Mutsuo Hatano 《Journal of the American Oil Chemists' Society》1995,72(11):1287-1291
Highly unsaturated fatty acid-containing phospholipids (HUFA-PL), which serve to increase the deformability of human red blood
cells, were prepared through porcine phospholipase A2-mediated esterification of the lysophosphatidylcholine, which was derived from soy phosphatidylcholine (PC), and by Lipozyme-mediated
acidolysis. Through these processes, phospholipase A2, with formamide as a water mimic, enhanced the incorporation of HUFA into positionsn-2 of PC and suppressed hydrolysis of the synthesized PL. On the other hand, Lipozyme-mediated acidolysis between positionsn-1 of soy PC and HUFA was enhanced by a combination of water and propylene glycol. Simultaneously, the recovered PL products
showed decreased hydrolysis of newly synthesized health-beneficial HUFA-PL. 相似文献