A new family of yeast genes implicated in ergosterol synthesis is related to the human oxysterol binding protein

We have identified three yeast genes, KES1, HES1 and OSH1, whose products show homology to the human oxysterol binding protein (OSBP). Mutations in these genes resulted in pleiotropic sterol-related phenotypes. These include tryptophan-transport defects and nystatin resistance, shown by double and triple mutants. In addition, mutant combinations showed small but apparently cumulative reductions in membrane ergosterol levels. The three yeast genes are also functionally related as overexpression of HES1 or KES1 alleviated the tryptophan-transport defect in kes1Δ or osh1Δ mutants, respectively. Our study implicates this new yeast gene family in ergosterol synthesis and provides comparative evidence of a role for human OSBP in cholesterol synthesis.     

求解机械装配规划的新方法

本文提出一个求解机械装配规划的算法,其计算量～O(sN~2),其中s是零件所有可能装配方向的个数,N是工件的零件数(一般s～O(N)).而现行的求机械装配规划的算法,其计算量均随N的增加按指数律增加.     

Improved coupled-mode theory for nonlinear directional couplers

An improved coupled-mode equation for nonlinear directional couplers (NLDC) with Kerr-like nonlinear media is proposed. The method is based on the generalized reciprocity relation in which two sets of field solutions satisfying Maxwell's equations are for the NLDC and for the isolated nonlinear waveguide. That leads to a reasonable result that all the coefficients in the coupled-mode equations, including the coupling coefficient, become power dependent. For the NLDC with a self-focusing or self-defocusing nonlinear material, the authors examine how the coupling coefficient, the coupling length, and the guided power depend on the input power in the range of coupling stronger than in previous reports. It is found that the critical power at which the coupling length becomes infinity does not increase as much with the two guides for the case of self-focusing media     

油脂己烷浸出工程进展

油脂己烷浸出工程经过几十年的发展，在工艺、设备、自控、节能、环保等方面都已趋于完善。装置的规模日趋大型化。车间内的工段组合更加科学、合理与多样化，浅料层浸出器，形式多样化的湿粕脱溶系统，湿粕挤压机，废水零排放系统，不同理念的负压蒸发及余热回收系统，蒸汽冷凝水的再利用，简洁实用的全电脑操作系统，分步萃取，混合油过滤，浸出车间内的混合油碱炼、水化脱胶、磷脂干燥等使得当今的油脂浸出向大型化、集约化、自动化、节能环保的方向发展，为客户提供了越来越多的选择。     

2#板坯连铸机振动台故障分析及改造

论述了银山型钢有限公司炼钢厂2#板坯连铸机自投产以来其振动台存在的问题，根据实际情况分析论证并进行改造实施，实施后效果明显。     

En/Decoder for Spectral Phase-Coded OCDMA System Based on Amplitude Sampled FBG

A novel en/decoder for spectral phase-coded optical code-division multiple-access system based on amplitude sampled fiber Bragg grating (FBG) is proposed. Both equivalent chirp and equivalent phase shift are achieved by amplitude sampling. Compared with previous en/decoder based on step chirped FBG, it is easier to fabricate. The performance of the proposed en/decoder is verified by both numerical simulation and experimental demonstration.     

Geotechnical properties of the soft soil in Guangzhou College City

The paper describes some geotechnical properties of the soft soils in Guangzhou College City, China, which are difficult to both sample and test. Laboratory and in situ tests were carried out to assess the physical and mechanical indices of the soils. The data were statistically analyzed and linear regression undertaken such that equations could be developed by which the geotechnical properties of the soft soils can be predicted. The statistical validity of the degree of correlation confirmed that using these equations, the mechanical indices can be estimated from physical indices determined by routine testing.      

Novel blood-compatible waterborne polyurethane using chitosan as an extender

A series of novel block polymers of polyurethane (PU) and chitosan have been prepared in two steps. The first step is the preparation of PU prepolymer, obtained from polytetramethylene oxide glycol (PTMO, M_n = 1000), isophrone diisocyanate (IPDI), and 2,2′-dimethylol propionic acid (DMPA), followed by ionizing PU prepolymer with triethylamine (TEA). The second step involves PU chain-extended by water-soluble chitosan of low molecular weight (M_n = 5000) by self-emulsion polymerization method. The sizes of the latex particles, morphology, and copolymer architecture have been characterized by dynamic light scattering (DLS), general tensile test, infrared spectroscopy (IR), surface contact angle measurement, and transmission electron microscopy (TEM). Furthermore, it shows that the addition of chitosan remarkably increases anticoagulative property of PU elastomers confirmed by the recalcification time. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008