Meniscal regeneration in the long-term after total meniscectomy?

A cohort of 39 patients (28 male, 11 female) that had undergone total meniscectomy as adolescents (mean age 16 years) underwent FISP 3D Magnetic Resonance Imaging at a mean follow up of 30 years. The presence of meniscal tissue was assessed by two independent observers blinded to the operation details. The volume of any meniscal tissue present was calculated. A posterior horn remnant was seen in 57% of medial and 45% of lateral meniscectomy cases. The mean volume of an operated medial meniscal remnant was 0.29 mL compared with a mean volume of 1.15 mL for an intact medial meniscus. The mean volume of an operated lateral meniscal remnant was 0.30 mL compared with 1.07 mL for an intact lateral meniscus. We have shown that the incidence of incomplete excision of the posterior horn is more common after total medial meniscectomy, and that at a mean follow up of 30 years there is no convincing in vivo MRI evidence of long-term meniscal regeneration.     

Transluminal balloon angioplasty, stents, and atherectomy

Arterial bypass grafting for occlusive disease is still considered the gold standard in the treatment of arterial occlusive disease. However, less invasive methods are available for select patients. Percutaneous balloon angioplasty has been shown to be effective in focal iliac artery stenosis, with patency rates of 50% to 90% at 5 years. Patency rates for femoropopliteal lesions are generally less than 50% at 2 years. Complications seen with balloon angioplasty often can be treated with arterial stents. Stents can be categorized into balloon-expandable, which provide a rigid scaffold to support the artery, self-expanding, which exert radial force to resist external compression, and thermal expanding stents, which allow for the use of a smaller introducer sheath. Another treatment option is atherectomy, in which the offending lesion is removed instead of fracturing and dilating the lumen. Although overall initial results of atherectomy have not been favorable, short lesions with eccentric atheroma or intimal hyperplasia, such as those seen in dialysis access fistulas or vein graft stenoses, may respond well.     

水利水电施工企业项目管理浅析

阐述了水利水电施工企业项目管理的特点,就本施工企业实行项目管理的实践情况作了介绍,对施工企业如何进行规范化项目管理提出了建议。     

Lithium-induced follicular hyperkeratosis

Scanning with Tc-99m labeled RBC was performed in two patients with recurrent postoperative gastrointestinal bleeding after partial colonic resection. Imaging correctly identified the source of bleeding at the anastomotic site in the large bowel, effectively contributing in the patient's treatment planning. Radionuclide scintigraphy provides a simple, noninvasive modality to diagnose and manage difficult clinical situations such as postoperative bleeding.     

An atomic model of the outer layer of the bluetongue virus core derived from X-ray crystallography and electron cryomicroscopy

BACKGROUND: Bluetongue virus (BTV), which belongs to the Reoviridae family and orbivirus genus, is a non-enveloped, icosahedral, double-stranded RNA virus. Several protein layers enclose its genome; upon cell entry the outer layer is stripped away leaving a core, the surface of which is composed of VP7. The structure of the trimeric VP7 molecule has previously been determined using X-ray crystallography. The articulated VP7 subunit consists of two domains, one which is largely alpha-helical and the other, smaller domain, is a beta barrel with jelly-roll topology. The relative orientations of these two domains vary in different crystal forms. The structure of VP7 and the organizations of 780 subunits of this molecule in the core of virus is central to the assembly and function of BTV. RESULTS: A 23 A resolution map of the core, determined using electron cryomicroscopy (cryoEM) data, reveals that the 260 trimers of VP7 are organized on a rather precise T = 13 laevo icosahedral lattice, in accordance with the theory of quasi-equivalence. The VP7 layer occupies a shell that is between 260 A and 345 A from the centre of the core. Below this radius (230-260 A) lies the T = 1 layer of 120 molecules of VP3. By fitting the X-ray structure of an individual VP7 trimer onto the cryoEM BTV core structure, we have generated an atomic model of the VP7 layer of BTV. This demonstrates that one of the molecular structures seen in crystals of the isolated VP7 corresponds to the in vivo conformation of the molecule in the core. CONCLUSIONS: The beta-barrel domains of VP7 are external to the core and interact with protein in the outer layer of the mature virion. The lower, alpha-helical domains of VP7 interact with VP3 molecules which form the inner layer of the BTV core. Adjacent VP7 trimer-trimer interactions in the T = 13 layer are mediated principally through well-defined regions in the broader lower domains, to form a structure that conforms well with that expected from the theory of quasi-equivalence with no significant conformational changes within the individual trimers. The VP3 layer determines the particle size and forms a rather smooth surface upon which the two-dimensional lattice of VP7 trimers is laid down.     

认知定位系统的自适应精度研究

为了能够实现定位精度的自适应,本文分析了认知无线电定位系统(cognitive positioning systems,CPS)的原理。该系统利用频谱及环境感知等模块中的传感器单元来获取所需的定位参数,并将其与到达时间(time of arrival,TOA)定位估计算法相结合,以克拉美罗下界(Cramer-Rao lower bound,CRLB)为准则分析最大似然(maximum likelihood,ML)定位精度自适应算法。本文还对单径和多径环境条件下定位精度自适应性能进行了比较。仿真结果表明,该算法能够实现定位精度的自适应,并能通过改善系统可用的频带带宽、分散频谱的数目、信号的调制方式等因素来提高定位精度。     

基于REST架构的矿山数字移动办公平台

基于面向资源思想以及REST架构,首次提出了矿山资源抽象层的概念,将矿山中各个异构系统的功能、文档、界面、工作流等抽象为能够通过标准URI来唯一标识的抽象资源元数据,在决策或智能分析层通过对元数据的分析和处理来实现相应操作或得出相关的分析结果;提出了基于REST框架的矿山数字移动办公平台设计方案,并以神木张家峁矿业有限公司移动办公平台的建设为例,介绍了将多个异构系统快速集成在移动终端的实现方法。应用结果表明,该移动办公平台运行稳定,操作流畅,使得工作人员能够随时、随地、随手办公,大大提高了办公灵活性及效率。     

从锌锗浸出液中提取锗的研究进展

锗资源开发对通讯和航空航天行业的发展具有重要的战略意义,由于提取锗的原料有限,所以开发和优化锗提取工艺受到日益关注.通过综述国内外从锌锗浸出液中提取锗的研究进展,对比多种锗的提取方法,总结出单宁沉锗法为应用最广泛的提锗方法.该方法具有绿色环保、操作简单的优点,但也存在单宁用量大,锗直收率低等问题亟待解决.基于超声波具有频率高、方向性好等优点,且已成功应用于湿法冶金工业中,因此进一步提出将超声外场引入单宁沉锗工艺中,并详细分析了超声外场强化的可行性和机理,以期降低单宁酸用量,提高锗直收率.指出超声外场强化单宁沉锗新工艺具有很好的研究和应用前景.     

多网融合方案在电力基建工程现场中应用研究

针对输变电工程陆续开展基建智慧工地,智慧物联系统平台建设已成为常态,目前建设思路主要是通过基于"大、云、物、移、智"开展新技术、新产品的应用,实现"人、机、料、法、环、测"等施工现场六要素的感知采集,以支撑智慧工地及基建信息化的业务开展.如何实现施工现场感知层数据、视频流数据以及业务数据三类数据的传输,并实现设备安装布设无线化、部署简易化,是重点思考和解决的方向,提出建设以5G(generation)专网为主,无线接入点(access point,AP)网络、远距离(long range,LoRa)通信网络为辅的多网融合方案,开展智慧工地网络层的建设,以支撑智慧工地物联网业务的开展,提供高质量、高体验的网络层支撑.