Constraint-based beautification and dimensioning of 3D polyhedral models reconstructed from 2D sketches

3D models reconstructed from 2D sketches are inaccurate because of the inherent inaccuracies in the input and the reconstruction method. It is therefore necessary to “beautify” them before use in CAD systems. We present a method that detects geometric constraints, such as parallel and orthogonal faces, present in the reconstructed model and then selects a subset that constrains the object sufficiently and consistently. The subset selection algorithm first prioritizes the constraints depending on their type and then uses a novel method, based on quasi-Newton optimization, to detect and eliminate redundant and inconsistent constraints. The remaining constraints then define the dimensions of the model fully and consistently. Results from our implementation show that the method can beautify and dimension recovered 3D models correctly at acceptable speed.     

信息化经济发展的新动力——写在石龙以宽带速度驶向E-TOWN之际

“我们在一个非常合适的时期,　在一个非常合适的地点,　召开了一个非常合适的会议。”在2003年的“中国城市信息技术应用高层论坛”上,中国市长协会副会长兼秘书长陶斯亮曾过这样一句话。这个“合适的地点”,就是石龙。 广东中心城镇——石龙　　　　美丽的东江蜿蜒而下的北干流与南支流交汇一处,形成一河三埠的风水宝地——石龙。石龙北靠广州,南临深圳,毗邻香港,距广州69公里,深圳78公里,历来都是东江水运的重要港口。　　　　石龙,已有800年的悠久历史,自宋代开始有人定居。由于东江穿境而过,航运极为便利,石龙在明末清…     

袖珍计算机放射性总量测量系统

本文介绍以PC-1500(A)型袖珍计算机为主体的地面放射性总量数据采集及处理系统的方案、硬件、软件及应用。     

用好炉温优化串级调控的探讨

将焦炉加热优化串级调控技术与焦炉加热DCS自动控制技术进行比较，叙述使用好炉温优化串级控制的措施及其效果。     

浅谈多媒体技术在数字图书馆中的运用

介绍了多媒体的概念、特点，探讨了多媒体在图书馆各项工作中的应用方式，论述了多媒体在图书馆应用中对读者产生的意义。     

用EGS4分析9MeV行波直线加速器屏蔽系统

采用了国际上广泛使用的ＭｏｎｔｅＣａｒｌｏ模拟计算程序ＥＧＳ４对海关集装箱检测系统用加速器屏蔽系统进行了辐射模拟分析，与实际测试数据进行分析、比较，解释了特殊剂量分布的原因，提出了系统改进的参考方案。     

秦山300MW核电机组全范围仿真机测试验收

介绍了秦山３００ＭＷ核电机组全范围仿真机的测试验收的整个过程，包括：验收测试规程的形成，工厂内部预测试和工厂用户测试。并分析了测试验收过程中存在的重大问题及解决的办法。     

Mechanical stretch induces hypertrophic responses in cardiac myocytes of angiotensin II type 1a receptor knockout mice

Many lines of evidence have suggested that angiotensin II (AngII) plays an important role in the development of cardiac hypertrophy through AngII type 1 receptor (AT1). To determine whether AngII is indispensable for the development of mechanical stress-induced cardiac hypertrophy, we examined the activity of mitogen-activated protein kinase (MAPK) family and the expression of the c-fos gene as hypertrophic responses after stretching cultured cardiac myocytes of AT1a knockout (KO) mice. When cardiac myocytes were stretched by 20% for 10 min, extracellular signal-regulated protein kinases (ERKs) were strongly activated in KO cardiomyocytes as well as wild type (WT) myocytes. Both basal and stimulated levels of ERKs were higher in cardiomyocytes of KO mice than in those of WT mice. Activation of another member of the MAPK family, p38(MAPK), and expression of the c-fos gene were also induced by stretching cardiac myocytes of both types of mice. An AT1 antagonist attenuated stretch-induced activation of ERKs in WT cardiomyocytes but not in KO cardiomyocytes. Down-regulation of protein kinase C inhibited stretch-induced ERK activation in WT cardiomyocytes, whereas a broad spectrum tyrosine kinase inhibitor (genistein) and selective inhibitors of epidermal growth factor receptor (tyrphostin, AG1478, and B42) suppressed stretch-induced activation of ERKs in KO cardiac myocytes. Epidermal growth factor receptor was phosphorylated at tyrosine residues by stretching cardiac myocytes of KO mice. These results suggest that mechanical stretch could evoke hypertrophic responses in cardiac myocytes that lack the AT1 signaling pathway possibly through tyrosine kinase activation.     

Uterine relaxation responses to calcitonin gene-related peptide and calcitonin gene-related peptide receptors decreased during labor in rats

OBJECTIVES: Our purpose was to investigate (1) whether uterine relaxation responses to calcitonin gene-related peptide are differentially regulated during pregnancy and labor, (2) the involvement of nitric oxide in smooth muscle relaxant action of calcitonin gene-related peptide in the rat uterus, (3) whether receptors for calcitonin gene-related peptide are expressed in rat uterus, and if so (4) whether the concentrations of these receptors are differently regulated during pregnancy and labor. STUDY DESIGN: Rats were killed on day 18 of gestation, at the time of spontaneous labor, or postpartum day 2. The uteri were removed for in vitro contractility measurements, nitric oxide production, and calcitonin gene-related peptide receptor binding assay. RESULTS: (1) Calcitonin gene-related peptide induced a dose-dependent relaxation in spontaneously contracting uterine strips from pregnant rats on day 18 of gestation; (2) the relaxation effects of calcitonin gene-related peptide on the uterus were decreased during spontaneous delivery at term and post partum compared with that during pregnancy; (3) calcitonin gene-related peptide-induced relaxation was inhibited by pretreatment of the uterine tissue with a calcitonin gene-related peptide receptor antagonist, calcitonin gene-related peptide(8-37); (4) nitric oxide synthesis inhibitor (N(G)-nitro-L-arginine methyl ester) and soluble guanylate cyclase inhibitor (LY83583) significantly decreased calcitonin gene-related peptide-induced relaxation of the rat uterus during pregnancy; (5) calcitonin gene-related peptide increased the uterine nitric oxide production in pregnant rats, and this increase was obliterated in the presence of calcitonin gene-related peptide(8-37); and (6) calcitonin gene-related peptide receptors are present in rat uterus, and the concentration of these receptors dramatically increases during pregnancy and decreases during labor at term. CONCLUSIONS: Calcitonin gene-related peptide inhibits uterine spontaneous contractions in rats during pregnancy but not during labor and post partum. The inhibitory effects of calcitonin gene-related peptide on uterine contractility appear to be modulated, at least in part, by the activation of nitric oxide generation in the rat uterus. Changes in calcitonin gene-related peptide receptors could contribute to the changes in calcitonin gene-related peptide-mediated uterine relaxation during pregnancy and labor.     

程控交换机收号系统模拟的研究

本文提出了一种模拟程控交换机收号系统的有效方法,采用消息驱动收号事件表的思想,运用并发控制技术,实现了在没有话路硬设备的条件下多用户同时拨号在线模拟收号控制的功能。本文提出的收号系统模拟方案已成功应用于某国产中大容量程控交换机的呼叫模拟系统中。