Optimal implementation of morphological operations on neighborhood-connected parallel computers

To efficiently perform morphological operations on neighborhood-processing-based parallel image computers, we need to decompose structuring elements larger than the neighborhood that can be directly handled into neighborhood subsets. In the special case that the structuring element is a convex polygon, there are known decomposition algorithms in the literature. In this paper, we give an algorithm for the optimal decomposition of arbitrarily shaped structuring elements, enabling an optimal implementation of morphological operations on neighborhood-connected parallel computers in the general case.     

Inhibition of microtubule assembly in tumor cells by 3-bromoacetylamino benzoylurea, a new cancericidal compound

We have synthesized a new compound, 3-bromoacetylamino benzoylurea (3-BAABU), which showed strong cancericidal activity by inducing irreversible mitotic arrest and subsequently apoptosis in human T cell leukemic cells (CEM), human biphenotypic leukemic cells (SP), a human prostate cancer cell line (PC-3), murine melanoma cells (B-16), and murine lymphoma/leukemia cells (EL4) in vitro with an ID50 in the range of 0.013-0.07 microg/ml (0.04-0.22 microM). Treatment of tumor cells for 12-24 h with 3-BAABU resulted in mitotic arrest at prometaphase/metaphase/anaphase, with separation and dispersion of chromosomes and with the absence of mitotic spindle apparatus in cytoplasm. Treatment with 3-BAABU had no cytotoxic and mitotic blocking effect in normal human lymphocytes, proliferating fibroblast cells (3T3), or proliferating myocardial cells (MOT). Cell cycle analyses showed that most treated leukemic cells accumulated at M phase 12 h after treatment. By the end of 48 h of treatment, the cells underwent apoptosis with DNA fragmentation. 3-BAABU inhibited the assembly of microtubules from tubulin but did not interfere with the disassembly of microtubules. The presence and the position of bromine and urea groups on the benzoic ring are the determining factors for its inhibition of microtubule assembly. Replacing bromine with chlorine yielded much less mitotic blocking activity and increased the ID50 40-fold. Substitution of the urea group with ethyl ester abrogated the activity of blocking mitosis but induced apoptosis. Moving the bromoacetylamino group from the 3-position to the 4-position removed blocking activity for mitosis but induced necrosis. These results suggest that 3-BAABU possesses a unique and functional structure and is a potential agent for cancer chemotherapy.     

Osteogenesis of electrically stimulated bone cells mediated in part by calcium ions

Culture selected and expanded osteoblastic cells may be able to be reintroduced into massive skeletal defects to accelerate cell mediated regeneration of skeletal tissues, especially in bone ingrowth in total joint replacement, fracture healing, and osteoporosis. In vitro osteogenic cell culture is a useful model in studying the mechanism of bone metabolism under direct current stimulation. In this study, an osteoblastlike cell line was isolated from newborn rat calvaria. The osteogenic processes of the in vitro cultured cell line were studied by cytochemical, electron microscopic, and energy dispersive x-ray analysis techniques that resembled those observed in membrane bone ossification centers in vivo. Direct current stimulation of 100 microA/cm2 accelerated greatly the proliferation and calcification of the in vitro cultured cells. Intracellular free calcium ion metabolism was measured with an Adherent Cell Analysis and Sorting Machine. Under direct current stimulation, intracellular free calcium ion concentration increased an average of 2.3 times of the original level, which may play a key role in regulating osteogenesis and bone metabolism.     

Determination of the epitope of an inhibitory antibody to proliferating cell nuclear antigen

We identified an expansion of the CAG trinucleotide repeat in the coding region of the Machado-Joseph disease gene in 7 of 24 American families diagnosed with autosomal dominant ataxia. All affected individuals were heterozygous for an expanded allele that ranged from 67 to more than 200 CAG repeats, whereas the normal allele had 14 to 33 repeats. In contrast to the Azorean-Portuguese origins of Machado-Joseph disease, the two largest American families were of German and Dutch-African descent. Clinical, pathologic, and genetic evaluations suggest that American families with spinocerebellar ataxia type 3 differ from those with Machado-Joseph disease by their ethnic origins, predominant spinopontine atrophy, lack of dystonic features, and larger CAG repeat expansion.     

最佳相位设计的MBE声码器语音合成

提出了一种基于最佳相位设计的语音合成技术,能够有效降低MBE声码器合成语音信号由于波形失衡而导致的饱和失真的概率.此外,为了保证合成滤波器的稳定性,对线谱频率(LSF)系数提取进行了优化.实验结果显示,合成语音信号波形近似平衡地分布在零幅度值的上下,语音听起来没有不舒服的感觉.实验结果表明,基于最佳相位设计的语音合成技术能够有效改善合成语音质量.     

基于AROP程序包的类Landsat遥感影像配准与正射纠正试验和精度分析

遥感影像的精确配准和正射纠正是进行图像融合、变化检测、图像镶嵌、定量遥感建模、多时相和多传感器影像协同应用的基础和前提。以美国国家航空和航天管理局下设LEDAPS(Landsat Ecosystem Disturbance Adaptive Processing System)课题组开发的配准与正射纠正程序包AROP(Automated Registration and Orthorectification Package)为例,详细阐述了其配准的原理与程序设计流程,并对其配准的精度进行了分析和评价。试验表明:AROP程序包算法能够找出足够的控制点,且控制点分布较为均匀,配准误差小于0.5个像元。误差特征表现为:扫描误差明显大于航向误差,误差的结果与影像漂移、DEM、坡度存在一定的相关性,高程和坡度是影响配准精度的主要因素之一。该程序包目前能够用于对我国CBERS影像的正射校正以及波段不匹配处理,但是对HJ卫星CCD影像数据配准还有待于进一步研究。     

Correction to: Parallel Single-Pixel Imaging: A General Method for Direct–Global Separation and 3D Shape Reconstruction Under Strong Global Illumination

International Journal of Computer Vision - In the original publication of the article, the name of the last author should be Yang Xu, instead of Xu Yang. “Xu” is the family name, and...     

双目视觉系统在风洞伞摆角测量中的研究与应用

伞系统是飞行器的重要组成部分,其摆角参数是系统安全性的重要指标之一;针对目前风洞试验中伞摆角难以测量的问题,提出了一种基于双目视觉系统的试验方法,该系统主要由两部CCD相机、图像采集卡和控制计算机组成,通过立体视觉标定和数字图像处理技术解算出空间特征标记的三维坐标,根据坐标的空间几何关系计算出伞摆角参数;试验结果表明该方法应用成功,能够同时获取伞运动过程中投影在正交平面上的竖直和水平摆角,且具有系统组成简单、通用性强的优点,有较高的应用价值。     

基于FPGA和ARM的弹上相位自动微调控制器设计与实现

为了提高相位自动微调控制器的控制性能,针对某型导弹,提出并实现了以ARM+ FPGA双微处理器为核心的硬件设计方案,采用了模糊PID控制算法,通过优化步进电机控制模式,提高了相位自动微调控制器的控制精度,将步进电机的调整时间由800 ms缩短到100 ms以内;该方案已成功应用于某型弹上系统,实践证明,该设计方案成本低、可扩展性强,能够满足系统控制需求,具有较高的实用性,大大提高了装备维护效率.