Decision Support System for Stakeholder Involvement

Stakeholder involvement is essential to the development of a total maximum daily load (TMDL) and its implementation plan. A tool, beyond a simulation model, is needed to support the decision making process that requires negotiation and compromise among stakeholders. The decision support system (DSS) described herein has a TMDL module to calculate various combinations of point and nonpoint loads that can meet the water quality criteria. Its Consensus module allows stakeholders to formulate, evaluate, modify, and vote for alternatives. The DSS displays bar charts for pollution loads from various subwatersheds and attributes the nonpoint loads to land uses. The water quality consequence of the pollution loads is output in maps, which shows sections meeting criteria in green and those not in red. The DSS requires a front end effort of site specific adaptation and model calibration. An Internet-based stakeholder process was developed to allow more concerned citizens to participate in management decisions.     

主动约束层阻尼板结构动力学建模研究

将有限元法和GHM法相结合，给出了建立主动约束层阻尼（ACLD）板结构动力学模型的新方法。建模时，考虑到粘弹材料（VEM）的纵向位移影响，采用GHM方法描述VEM的本构关系，解决了VEM的力学特性随温度和频率变化的难点，避免因VEM的复杂本构关系而产生的微分积分方程。算例表明本文给出的建模方法是准确的，ACLD结构能够有效控制结构振动。     

Renal R2 chemoreceptor activity is attenuated after back heating in the rat

The aim of the present study was to determine the afferent connections of the nucleus accumbens in snakes, in particular its catecholaminergic input. For that purpose, in vitro and in vivo applications of retrograde tracers in the nucleus accumbens of Elaphe guttata were combined with tyrosine hydroxylase (TH) immunohistochemistry. Both techniques revealed telencephalic inputs to the nucleus accumbens originating from the diagonal band of Broca, ventral pallidum, amygdaloid complex, and dorsal cortex. Major diencephalic inputs arise from the dorsomedial thalamic nucleus and the hypothalamus. In the brainstem, a few retrogradely labeled cells were observed in the raphe nucleus and the locus coeruleus. Considerably more cells were found in the midbrain tegmentum. Within the confines of the locus coeruleus and, in particular, the midbrain tegmentum, retrogradely labeled cells stained also for TH suggesting that those areas constitute the major catecholaminergic input to the nucleus accumbens of snakes. The experimental approach used in the present study, in particular the in vitro technique, seems to be very suited for studying the development of basal ganglia organization of reptiles in the near future.     

NMR structure and mutagenesis of the FADD (Mort1) death-effector domain

When activated, membrane-bound receptors for Fas and tumour-necrosis factor initiate programmed cell death by recruiting the death domain of the adaptor protein FADD to the membrane. FADD then activates caspase 8 (also known as FLICE or MACH) through an interaction between the death-effector domains of FADD and caspase 8. This ultimately leads to the apoptotic response. Death-effector domains and homologous protein modules known as caspase-recruitment domains have been found in several proteins and are important regulators of caspase (FLICE) activity and of apoptosis. Here we describe the solution structure of a soluble, biologically active mutant of the FADD death-effector domain. The structure consists of six antiparallel, amphipathic alpha-helices and resembles the overall fold of the death domains of Fas and p75. Despite this structural similarity, mutations that inhibit protein-protein interactions involving the Fas death domain have no effect when introduced into the FADD death-effector domain. Instead, a hydrophobic region of the FADD death-effector domain that is not present in the death domains is vital for binding to FLICE and for apoptotic activity.     

The complexity of oblivious plans for orienting and distinguishing polygonal parts

In the problem ofparts feeding we are given a class of feasible operations for reorienting a part, and we are asked to find a fixed sequence of these operations which is guaranteed to bring the part into a known goal orientation from any possible initial orientation. Goldberg addressed this problem in [2], and showed that, for planar polygonal parts, there is always a sequence of simple operations which can be performed by a simple parallel-jaw gripper, which is guaranteed to orient the part (up to symmetry) without the use of any sensor information; he also conjectured thatO(n) steps are sufficient.In this paper we prove Goldberg's conjecture by explicitly constructing plans of at most2n – 1 steps for orienting polygonal parts in this model. We also give a lower bound on the number of steps required for such plans to show that this upper bound is tight.Finally, we extend these results to the problem ofdistinguishing among a finite set of parts using minimal sensing. Specifically, we assume that we are given a set of known polygonal parts, and a parallel-jaw gripper able to sense the distance between its jaws upon closure. We construct a simple oblivious plan of linear complexity which, when presented with a polygonal part, determines the index of this part.This research was supported in part by the NSF under Grant CCR-9207422, and by a Zumberge Fellowship. A preliminary version of this paper appeared in theProceedings of the Fourth Canadian Conference on Computational Geometry [1].     

Experimental realization of a new transistor

The authors report on the fabrication and characteristics of a unipolar, three-terminal, resonant-tunneling transistor. The operating principle of this new transistor is based on the fact that the quantum mechanical resonant-tunneling probability of hot electrons between the emitter and the collector is switched almost completely on and off, when either the base or the collector bias is swept. The emitter injects hot electrons to the second lowest subband of a thin (100 Å in this work) GaAs quantum well. Subsequently, the hot electrons will either resonantly tunnel to the collector, or relax to the lowest subband and contribute to the base current. As a result of resonant transmission, at 77 K the current-voltage characteristics of the transistor display negative differential resistance with extremely large (4691) peak-to-valley ratio. Furthermore, when biased near resonance, a maximum DC current gain of ~1.2 and a maximum AC current gain of ~11.9 were observed. The first use of a new `tunneling-in and tunneling-out' scheme in contacting a thin quantum well is also demonstrated     

随机模拟在电信网性能评价中的应用

本文介绍了可在微机上实现大规模电信网践模拟的实用化软件ＳＩＭＵＮＥＴ，及基所采用的无时钟事件追踪法。该软件可用规划中的电信网络和实际网路的模拟及性能评价，也可用于不同流量控制算法的评价。文中给出一个评价实例。     

Static and dynamic analysis of tunable two-section high-speeddistributed feedback laser utilizing the gain lever effect

Analysis of a novel semiconductor laser structure designed for obtaining wide tuning range along with high speed modulation response is presented. The laser consists of a composite cavity structure with two active (gain) sections. One of the sections has a grating corrugation while the other is flat. A detailed round-trip analysis is combined with the rate equations, which include sublinear gain/carrier relation, to perform steady-state and small-signal analysis. It is shown that the biasing (dc) condition of the different sections plays a critical role in the determination of the dynamic response of the device. In addition, we show that the gain-lever effect can be utilized for a considerable enhancement of the frequency modulation (FM) response. Other critical structural parameters such as the grating coupling coefficient and device geometry are discussed