Electron spin resonance of DNA irradiated with a heavy-ion beam ([16]O[8+]): evidence for damage to the deoxyribose phosphate backbone

A major problem in the intensive care unit nowadays is the development of multiple organ dysfunction syndrome (MODS), a cumulative sequence of progressive deterioration of organ functions. While the pathogenic pathways of MODS remain to be elucidated, it is assumed that cells of the host defence system, especially the macrophages, are altered in their function. During the development of MODS it is assumed that macrophages are overactivated and that an exaggerated inflammatory response may contribute to its pathogenesis. In order to gain insight into the alterations of the functional status of the macrophage during the development of MODS, a series of macrophage functions was measured in the subsequent phases of zymosan induced generalized inflammation in mice. Male C57BL/6 mice received a single dose of zymosan intraperitoneally and groups of animals were killed after 2, 5, 8, and 12 days. Peritoneal macrophages were collected for in vitro assessment of the ADCC, the production of superoxide (O2-) and nitric oxide (NO), and complement mediated phagocytosis and intracellular killing of Staphylococcus aureus. A single intraperitoneal injection with zymosan resulted in a three-phase illness. During the third phase the animals developed MODS-like symptoms. Peritoneal cells from control animals produced very low to non-detectable amounts of O2- and NO, and the cytotoxic activity was also low. During the development of MODS, from day 7 onwards, the ability to produce O2- and NO2- became strongly elevated, as did the cytotoxic activity. These findings are in parallel with the development of MODS whereas the phagocytic and killing capacity remained essentially unaltered. The changes found could be detrimental for the organism, thus possibly contributing to the onset and development of MODS.     

铂与氢、水和苯分子相互作用的量子化学研究

采用量子化学程序Gaussian98(A.9)从头算的B3LYP方法，全优化计算铂对氢、水和苯的化学吸附作用，得到了3种相关络合物PtX、PtXX和Ptxxx(X=H，H2O或C6H6)的平衡几何构型和电子结构信息，并探讨了这些络合物的成键性质，以及苯环与铂原子之间的分子轨道作用性质。结果表明，苯环与铂原子之间有很强的成键作用，并随着游离氢原子和水分子的参与，作用强度有很大变化。苯分子吸附在金属铂上，它的芳香性得到不同程度的降低，苯环被活化，苯环与铂原子之间形成η^2型π键络合物；水参与作用后，苯环与铂原子之间形成σ络合物；氢和水同时参与作用后，苯环与铂原子之间仅有很弱的π轨道作用。     

EDTA络合滴定法定量测定油田水中SO42-的一项改进

测量油气田水中SO4^2-的EDTA络合滴定法在2000年及以后的石油天然气行业标准（SY／T5523（（油气田水分析方法》）中已废止。本工作发现稀释受测水样所用蒸馏水要消耗EDTA，导致测量误差。基于1992年版行业标准，提出了增加蒸馏水校正项的EDTA络合滴定法。将此改进方法用于含各种不同共存离子的自配盐水样中SO4^2-的测量，结果如下：不含SO4^2-的水样SO4^2-测量值均为零；测量结果不受共存离子种类和种数的影响；测量值的相对误差随SO4^2-质量浓度P的增大而减小，P〉1000mg／L时为0、4％～1．0％，P在227．30～755．50mg／L范围时为-5．8％～＋5、8％。均与ICP法十分接近；P在34、97-78、05mg／L范围时测量值相对误差为-8.9％～-13．1％；P低于30mg／L时测量误差很大，此法不适用。重量法用于盐水样中SO4^2-测量时误差很大或测不出。此法用于梁南地层水中SO4^2-的测量，测量值相对于ICP法测量值（340．40～1082．36mg／L）的误差为-2．2％～＋5．1％。表3参4。     

High-level synthesis design flow for power side-channel security

The lack of efficient security guidance is a prominent problem in the design flow of high-level synthesis. To tackle this issue, this paper proposes a security-based high-level synthesis design flow featuring the power side-channel vulnerabilities. The side-channel leakage is quantified by establishing a secure component module library, a more efficient and secure parallel scheduling mechanism is generated by optimizing the control flow, and a more secure architecture of the storage system is achieved by optimizing the data flow. The goal is to perform tradeoffs between performance and security, reducing the side-channel risks at the early stage of design and simultaneously generating more secure and efficient cryptographic cores in hardware. Furthermore, the proposed HLS design flow is verified on a field programmable gate array platform. Experimental results show that, in comparison with the traditional design flow, this method reduces the resources by 72% and the clock cycles by 70% and increases the throughput by 88%, and that it can lower the power side-channel risks within an ongoing design to the greatest extent.     

Computer Simulation of the Structure and Propertiesof Nanocrystals

This paper provides a computer modeling method for the study of nanocrystals. Structural features,such as the boundary component proportion, the reduced density proportion, the excess lattice parameter, and the radial distribution function, have been atomistically simulated. The energy and elastic properties also have been investigated. Simulation results indicate that the structure of grain boundaries in nanocrystals is different from those of the amorphous and the gas, or rather, it is a special structure with some degree of short-range order. Moreover, the structure of crystallites is not entirely the same as that in the perfect crystal lattice. The present simulation method may become one of the foundations of the theoretical study of nanocrystals.     

研究动画角色的类型化、系列化

动画角色类型化、系列化设计是动漫产业向多元化发展的一环,它能使动画片中角色更感人,更具明星效应,同时产生更大的商业附加值。在我国,动画角色造型质量上不去这一现象,这已成为阻碍中国动画设计产业不断发展的重要瓶颈。文章主要分析美国、日本经典动画片中角色的类型化、系列化,找到他们合乎时代要求并成功的原因,得出趋同、趋异的动画角色系列化设计方法,为创新角色设计找到可以依据的途径。     

一种动态Q值多标签识别算法的性能分析

EPCglobal组织发布的第二代超高频射频识别空中接口协议EPC-C1G2协议可同时识别多个标签,该协议采用时槽ALOHA算法来解决多标签识别时产生的碰撞问题。文章首先介绍了EPC-C1G2协议多标签碰撞解决所需的参数和命令,指出协议中的Q值决定了解决碰撞时所用的时槽数。时槽数越多,标签越不容易碰撞,但识别时间越长,因此,恰当地选择Q值可以在标签识别时间和识别标签数之间找到最佳点。文中同时给出了一种动态Q值算法,该算法可根据标签碰撞解决的实际情况动态调整Q值,使标签识别更高效。文章最后对这种多标签识别流程的性能进行了仿真分析。     

基于DWT的水印嵌入规则性能研究

在数字水印研究中,一个重要的问题是水印的不可见性与鲁棒性之间的折中。根据实际应用,数字水印的嵌入规则主要有乘性规则、加性规则和一种区域融合嵌入规则。本文主要从数字水印的抗攻击性方面,结合不同的嵌入规则,对各种常见图像攻击进行测试,在检测不同嵌入规则性能优劣的同时,为水印方法的选择与应用,提供指导和参考,以达到最佳的使用目的。     

环境荷载联合作用下海上风电结构动力响应分析

为研究海上风电结构在复杂的海洋环境中承受环境荷载(风、波、冰、流)的联合作用时,结构产生的剧烈的动力响应问题。文章以三脚架基础海上风电结构为研究对象,采用ANSYS有限元软件建立其整体模型并进行荷载(风、波、流和风、冰、流)联合作用下的静力校核,通过对环境荷载联合作用下的三脚架基础海上风电结构进行瞬态分析,掌握其动力响应的特性及规律。结果表明:三脚架基础结构的一、二阶自振频率均为0.285Hz,在所选风机允许的频率范围内,可以保证整体结构不会与风机转动发生共振;风荷载在风、波、流荷载联合作用下主导控制结构响应的稳态波动,冰荷载在风、冰、流荷载联合作用下主导控制结构的稳态振动过程;塔筒顶端呈现的位移和加速度响应均远大于三脚架基础顶端;环境荷载联合作用下结构动力响应是环境荷载单独作用下动力响应叠加的结果。