用修正淬透性系数法对反应堆压力容器锻件RTNDT数值的预估

分析反应堆压力容器(RPV)锻件制造过程中关键化学元素含量及基准无塑性转变温度(RTNDT)数值,通过引入修正淬透性系数,建立了反映RTNDT变化规律的修正淬透性系数函数表达式,并给出了实例验证,结果表明,通过本文建立的修正淬透性系数函数式可以比较精确地预估RPV锻件的RTNDT值。     

基于Newton-Raphson算法的COSINE热工水力程序安注箱模块研发

COSINE软件包是国家核电技术有限公司北京软件技术中心自主研发的堆芯设计和安全分析一体化软件包,安注箱是该软件包用于压水堆核电厂主回路分析的重要设备。本文介绍了基于NewtonRaphson算法建立的安注箱模型,该模型采用半隐式离散方法,程序的四个守恒方程采用有限体积法,其方程分别为:不凝气体质量守恒方程,液相质量守恒方程、气相动量守恒方程以及气相能量守恒方程。守恒方程考虑惯性力,壁面摩擦,局部阻力损失以及重力等因素影响。利用COSINE安注箱模型和参考程序RELAP5计算结果对比,两者计算结果误差较小,吻合较好;结果表明:COSINE安注箱模型能正确模拟安注箱,个别情况下COSINE安注箱模块更具稳定性和收敛性。     

核设备抗震鉴定试验中功率谱密度检验方法分析评估

为满足核设备抗震鉴定试验中输入运动的功率谱密度(PSD)要求,基于对规范背景和目标PSD算法的调研以及典型算例的对比分析,对PSD的检验方法进行分析评估。结果表明,检验PSD最为直观的方法即对比输入运动PSD与目标PSD;根据各类目标PSD算法的结果精度、保守性及其规范依据,推荐使用2014版美国核管理委员会标准审查大纲(SRP)3.7.1节附录B中人工合成时程的方式来计算目标PSD:虽然该算法通常适用于核电厂的厂址设计反应谱,但对于设备抗震鉴定反应谱,仅需将人工合成时程的目标反应谱替换为鉴定反应谱即可;采用本文推荐方法计算目标PSD时,设备抗震鉴定输入运动的PSD检验应与SRP 3.7.1保持一致,即在0.3 Hz到目标反应谱的最高截断频率范围内包络目标PSD的70%。     

Synthesis and dissociation of soliton molecules in parallel optical-soliton reactors

Mode-locked lasers have been widely used to explore interactions between optical solitons, including bound-soliton states that may be regarded as"photonic molec...     

大数据、云计算在轨道交通工程中的应用需求

大数据、云计算、移动互联网等新兴行业和新技术正在改变着传统的勘察设计、工程建设管理及维护模式。当前轨道交通领域的设计阶段已基本实现了数字化,但在某些环节数据管理与处理能力仍需加强,更由于施工和运营阶段数据管理与处理手段、能力的限制,使得设计成果未能得到充分应用,难于实现全阶段信息的集成和共享,制约了轨道交通领域的信息化建设。从庞杂的资料或海量数据中研究应用大数据、云计算技术解决问题的途径是轨道交通工程信息化需要解决的关键问题之一。由于轨道交通工程领域对大数据和云计算技术研究起步较晚,目前这些技术能用到该领域全生命周期哪些方面是值得研究的问题。本文结合大数据和云计算的特点,对轨道交通工程规划、设计、施工、运营维护各阶段可能的应用需求进行分析,旨在为今后研究工作提供参考。     

牛乳过敏原及加工技术对其致敏性的影响

对婴幼儿来说,牛乳营养丰富,是母乳最好的替代品,但牛乳中的蛋白质可能会引起过敏。牛乳中的主要过敏原是酪蛋白、β-乳球蛋白和α-乳白蛋白。本文从牛乳过敏原的结构和抗原表位、热处理、发酵和酶处理等不同的加工技术对牛乳蛋白致敏性的影响和过敏原标记检测方法三个方面进行了综述,为开发低致敏牛乳制品提供借鉴。      

Genetic Dissection of Phosphorus Use Efficiency and Genotype-by-Environment Interaction in Maize

Genotype-by-environment interaction (G-by-E) is a common but potentially problematic phenomenon in plant breeding. In this study, we investigated the genotypic performance and two measures of plasticity on a phenotypic and genetic level by assessing 234 maize doubled haploid lines from six populations for 15 traits in seven macro-environments with a focus on varying soil phosphorus levels. It was found intergenic regions contributed the most to the variation of phenotypic linear plasticity. For 15 traits, 124 and 31 quantitative trait loci (QTL) were identified for genotypic performance and phenotypic plasticity, respectively. Further, some genes associated with phosphorus use efficiency, such as Zm00001eb117170, Zm00001eb258520, and Zm00001eb265410, encode small ubiquitin-like modifier E3 ligase were identified. By significantly testing the main effect and G-by-E effect, 38 main QTL and 17 interaction QTL were identified, respectively, in which MQTL38 contained the gene Zm00001eb374120, and its effect was related to phosphorus concentration in the soil, the lower the concentration, the greater the effect. Differences in the size and sign of the QTL effect in multiple environments could account for G-by-E. At last, the superiority of G-by-E in genomic selection was observed. In summary, our findings will provide theoretical guidance for breeding P-efficient and broadly adaptable varieties.     

Preparation and Characterization of Nanofibrous Membranes Electro-Spun from Blended Poly(l-lactide-co-ε-caprolactone) and Recombinant Spider Silk Protein as Potential Skin Regeneration Scaffold

Biomaterial scaffolding serves as an important strategy in skin tissue engineering. In this research, recombinant spider silk protein (RSSP) and poly(L-lactide-co-ε-caprolactone) (PLCL) were blended in different ratios to fabricate nanofibrous membranes as potential skin regeneration scaffolds with an electro-spinning process. Scanning electron microscopy (SEM), water contact angles measurement, Fourier transform infrared (FTIR) spectroscopy, wide angle X-ray diffraction (WAXD), tensile mechanical tests and thermo-gravimetric analysis (TGA) were carried out to characterize the nanofibrous membranes. The results showed that the blending of RSSP greatly decreased the nanofibers’ average diameter, enhanced the hydrophilicity, changed the microstructure and thermal properties, and could enable tailored mechanical properties of the nanofibrous membranes. Among the blended membranes, the PLCL/RSSP (75/25) membrane was chosen for further investigation on biocompatibility. The results of hemolysis assays and for proliferation of human foreskin fibroblast cells (hFFCs) confirmed the membranes potential use as skin-regeneration scaffolds. Subsequent culture of mouse embryonic fibroblast cells (NIH-3T3) demonstrated the feasibility of the blended membranes as a human epidermal growth factor (hEGF) delivery matrix. The PLCL/RSSP (75/25) membrane possessed good properties comparable to those of human skin with high biocompatibility and the ability of hEGF delivery. Further studies can be carried out on such membranes with chemical or genetic modifications to make better scaffolds for skin regeneration.     

Conservation Study of Imprinted Genes in Maize Triparental Heterozygotic Kernels

Genomic imprinting is a classic epigenetic phenomenon related to the uniparental expression of genes. Imprinting variability exists in seeds and can contribute to observed parent-of-origin effects on seed development. Here, we conducted allelic expression of the embryo and endosperm from four crosses at 11 days after pollination (DAP). First, the F1 progeny of B73(♀) × Mo17(♂) and the inducer line CAU5 were used as parents to obtain reciprocal crosses of BM-C/C-BM. Additionally, the F1 progeny of Mo17(♀) × B73(♂) and CAU5 were used as parents to obtain reciprocal crosses of MB-C/C-MB. In total, 192 and 181 imprinted genes were identified in the BM-C/C-BM and MB-C/C-MB crosses, respectively. Then, by comparing the allelic expression of these imprinted genes in the reciprocal crosses of B73 and CAU5 (BC/CB), fifty-one Mo17-added non-conserved genes were identified as exhibiting imprinting variability. Fifty-one B73-added non-conserved genes were also identified by comparing the allelic expression of imprinted genes identified in BM-C/C-BM, MB-C/C-MB and MC/CM crosses. Specific Gene Ontology (GO) terms were not enriched in B73-added/Mo17-added non-conserved genes. Interestingly, the imprinting status of these genes was less conserved across other species. The cis-element distribution, tissue expression and subcellular location were similar between the B73-added/Mo17-added conserved and B73-added/Mo17-added non-conserved imprinted genes. Finally, genotypic and phenotypic analysis of one non-conserved gene showed that the mutation and overexpression of this gene may affect embryo and kernel size, which indicates that these non-conserved genes may also play an important role in kernel development. The findings of this study will be helpful for elucidating the imprinting mechanism of genes involved in maize kernel development.