Large capacitance and fast polarization response of thin electrolyte dielectrics by spin coating for two-dimensional MoS2 devices

Nano Research - A spin-coating method was applied to obtain thinner and smoother PEO/LiClO4 polymer electrolyte films (EFs) with a lower level of crystallization than those obtained using a...     

Peptidyl Virus-Like Nanovesicles as Reconfigurable “Trojan Horse” for Targeted siRNA Delivery and Synergistic Inhibition of Cancer Cells

The self-assembly of peptidyl virus-like nanovesicles (pVLNs) composed of highly ordered peptide bilayer membranes that encapsulate the small interfering RNA (siRNA) is reported. The targeting and enzyme-responsive sequences on the bilayer's surface allow the pVLNs to enter cancer cells with high efficiency and control the release of genetic drugs in response to the subcellular environment. By transforming its structure in response to the highly expressed enzyme matrix metalloproteinase 7 (MMP-7) in cancer cells, it helps the siRNA escape from the lysosomes, resulting in a final silencing efficiency of 92%. Moreover, the pVLNs can serve as reconfigurable “Trojan horse” by transforming into membranes triggered by the MMP-7 and disrupting the cytoplasmic structure, thereby achieving synergistic anticancer effects and 96% cancer cell mortality with little damage to normal cells. The pVLNs benefit from their biocompatibility, targeting, and enzyme responsiveness, making them a promising platform for gene therapy and anticancer therapy.     

车辆四轮转向系统的控制方法

系统地评述了车辆四轮转向系统的原理及其控制方法的发展,在此基础上指出四轮转向系统的研究必须以闭环综合评价为出发点,并与其它主动安全技术相结合才能真正达到实用阶段。     

基于范畴论的多TBox整合研究

在语义Web环境下,单一和分散的知识库会引发数据的冗余和不一致性,且严重影响知识库智能化查询,降低知识库中数据的重用性和可操作性.文中提出一种基于范畴论的多TBox整合方法来整合知识库,旨在解决上述者类问题.此方法具有高度抽象性和强大表达能力的范畴论是多知识库整合的理想工具.将TBox作为操作对象,范畴论中"态射"功能可实现TBox的映射,"外推"功能可实现TBox的整合,最后通过实验验证方法的可行性和有效性,实验结果基本符合要求.     

EDA9033A在分布式风机性能测试系统中的应用

针对以单片机为核心的风机性能测试系统存在稳定性差、抗干扰能力差、精度低等问题,开发了以PLC为核心、采用互感式采集模块EDA9033A采集风机电参数的分布式风机性能测试系统,给出了该风机性能测试系统的结构,详细介绍了EDA9033A的硬件及软件设计。实际应用表明,EDA9033A采集的风机电参数结果稳定、快速、准确。     

初探民间竹制品之设计意匠——以浙江省缙云地区竹制品的研究为例

英国学者李约瑟在深入研究中国科技史后认为,东亚文明乃是"竹子文明,中国人民的血液里流着竹子的文化"。我国不仅竹资源丰富,更是在竹资源的开发与利用上历史最为悠久的国家。我国南方有着大面积的竹产地,竹子及竹制品对当地的社会经济、民俗文化都有很大的影响。如何对"竹"这一传统材料进行创新性的开发和利用,最大限度的实现竹自身的价值,使制竹产业焕发出新的活力,成为当前研究的主要问题。     

Utility function of TCP

Understanding the TCP congestion control mechanism from a global optimization point of view is not only important in its own right, but also crucial to the design of other transport layer traffic control protocols with provable properties. In this paper, we derive a global utility function and the corresponding optimal control law, known as TCP control law, which maximizes the global utility. The TCP control law captures the essential behaviors of TCP, including slow start, congestion avoidance, and the binary nature of congestion feedback in TCP. We find that the utility function of TCP is linear in the slow start phase and is proportional to the additive increase rate and approaches the well-known logarithm function as the data rate becomes large in the congestion avoidance phase. We also find that understanding the slow start phase with a fixed threshold is critical to the design of new transport layer control protocols to enable quality of service features. Finally, as an application, we design a Minimum Rate Guaranteed (MRG) traffic control law that shares the same utility function as the TCP control law. Our simulation study of the MRG control law indicates that it is indeed TCP friendly and can provide minimum rate guarantee as long as the percentage of network resource consumed by the MRG flows is moderately small.     

CS-Chord:基于聚类分离的分布式高维向量索引

M-Chord是一种基于P2P网络的高维向量索引,其聚类边缘的向量容易与搜索圆频繁相交,使得查找的区域增多,降低了M-Chord的效率。提出一种基于聚类分离的分布式高维向量索引(CS-Chord),将边缘区域的高频检索向量从Chord环中分离出来,集中存储在服务器上,中心区域的向量仍存储于Chord环中,节省了大量资源的定位时间,从而提高检索效率。实验结果表明:在查询半径为0.2时,CS-Chord距离计算次数约为2000,比M-Chord减少了约2500次;CS-Chord消息转发次数约降低150次,仅为M-Chord的50%。