Effects of capsules on attachment of human periodontal ligament fibroblasts to root surface

The stability of cimetidine (Tagamet) was investigated in total parenteral nutrition (TPN) mixtures containing different amino acid sources. TPN mixtures were stored at 5 degrees C in ethylvinyl acetate bags for 28 days and analysed by stability-indicating high-pressure liquid chromatography. Results indicated that cimetidine was physically compatible and chemically stable (less than 5% degradation) for at least 28 days in TPN mixtures containing either Freamine III, Vamin 14 or Aminoplex 12 as the amino acid source.     

Ginkgolides antagonizing some effects of platelet-activating factor in vitro

The mixture of platelet-activating factor (PAF) and platelets produced significant contraction of guinea pigs' bronchus, while the contraction induced by PAF alone was mild relatively, the IC50 were 6.14 x 10(-7) mol/L and 6.32 x 10(-4) mol/L respectively. There was significant difference between these two groups (P < 0.05). When the platelets were pre-incubated with ginkgolides for 10 minutes in Tris-Tyrode's buffered saline, effects of the PAF and platelets mixture were significantly inhibited (P < 0.01). Exposure of guinea pigs' bronchus to PAF in vitro resulted in a loss of beta-adrenergic receptors and responses to isoproterenol, and this effect of PAF was prevented by prior incubation of the guinea pigs' bronchus with ginkgolides (P < 0.05). The results showed ginkgolides were a potent PAF antagonist.     

上海市吴淞工业区大气PM2.5水溶成分的元素分析及细胞毒性研究

通过ICP-MS测定了上海市吴淞地区大气PM2.5水溶成分金属元素含量,通过四唑盐(MTT)测定细胞存活率,通过超氧化歧化酶(SOD)和丙二醛(MDA)两个指标测定细胞氧化损伤,琼脂糖凝胶电泳测定细胞内DNA损伤,流式细胞仪(Flow cytometry)检测细胞凋亡和周期等实验研究了大气PM2.5水溶成分的细胞毒性.实验结果表明:PM2.5可溶成分中Zn元素含量最高,PM2.5在一定浓度范围内能导致细胞死亡,引起细胞的氧化损伤,影响DNA的复制,阻碍细胞增殖,但没有诱导细胞凋亡.PM2.5中可溶金属离子对细胞毒性表现为联合作用.     

环境放射化学研究中几个问题的讨论

本文从辐射环境保护和公众辐射防护的角度，讨论了放射性核素在环境中的迁移行为，放射性核素与环境介质的相互作用和放射性核素在环境中的形态等涉及到环境放射化学研究方向的问题，并讨论了它们之间相互依存的关系。     

西门子S7-200可编程控制器在气化油点火技术中的应用

以西门子S7—200PLC为核心。利用火检探头。温度、压力等传感器，结合STEP 7 MicmwIN V3．1以及ProTool Pro CS工业组态软件完成了对点火过程的自动控制。实现了西门子S7—200PLC在大型发电厂410吨级蒸汽锅炉“气化油直接点燃煤粉技术”中的应用。提高了锅炉点火系统运行的自动化水平。     

Neuroendocrine synaptic vesicles are formed in vitro by both clathrin-dependent and clathrin-independent pathways

Hereditary nonpolyposis colorectal cancer (HNPCC) is a syndrome involving a predisposition to cancers of the colon, endometrium and several other extra-colonic sites, accounting for approximately 1-5% of all colorectal cancer cases. It is not easily recognized because of a lack of distinctive clinical markers, making diagnosis and management of this disease problematic. To provide a basis for uniformity in diagnosis of HNPCC, the Amsterdam criteria were proposed and are currently in use. More recently, the discovery of four human mismatch repair genes (hMSH2, hMLH1, hPMS1 and hPMS2) has provided novel insight into the genetic basis of this disease, and raised the possibility of genetic diagnosis for management of HNPCC patients and their family members. This report summarizes the clinicopathologic aspects of HNPCC, reviews the recent genetic findings and surveillance strategies, and suggests a novel designation of certain patients as suspected HNPCC.     

堆底熔穿事故的场外后果及其对策

在压水堆核电站应急计划和应急响应中，堆底熔穿事故占有重要位置。本文用法国核电厂事故源项Ｓ３（对应于堆底熔穿事故）计算了在典型气象条件下的场外放射学的后果，根据一般防护决策原则和我国颁布的干预水平，提出了保护公众的应急防护措施的建议。     

Prediction of postoperative knee flexion in Insall-Burstein II total knee arthroplasty

Postoperative knee flexion in patients undergoing Insall-Burstein-II total knee arthroplasty at 2 years was evaluated regarding two basic questions: what groups of patients gain or lose the most flexion and what groups of patients have the best or worst postoperative flexion. Thirteen preoperative variables (maximum flexion, flexion arc, tibiofemoral angle, quadriceps strength, extensor lag, Knee Society score, Knee Society patient assessment, gender, age, height, weight, diagnosis, and surgeon) and four postoperative variable (leg length change, tibiofemoral angle, distance from patella to the joint line, and the tibial prosthesis anteroposterior translation on a lateral radiograph) were used in an attempt to explain postoperative flexion. The analysis was performed on 164 consecutive Insall-Burstein-II total knees in which the data were gathered prospectively on a time oriented medical record database. A regression tree analysis was used to identify several groups of patients, characterized by preoperative factor values, who had markedly above average performance on postoperative flexion. The preoperative factors identified include preoperative flexion, flexion arc, tibiofemoral angle, extensor lag, diagnosis, and age. The only postoperative variable of significance was tibiofemoral angle. Among the potential determinants of postoperative flexion that failed to appear predictive were the Knee Society scores and surgeon. Preoperative flexion is known to be a critical determinant of postoperative flexion in total knee replacement. However, in the current study, preoperative flexion accounted for only half of the difference between the best (122 degrees) and the worst (88 degrees) group, as determined with regression tree analysis.