VS2005—高校实验设备网络化管理的利器

高校实验设备实施网络化管理,能够极大提高设备信息的透明度,提高实验设备管理的效率,进一步优化管理工作.VS2005是开发高校设备管理网站的一种简单易学、功能强大的工具.现给出了一个基本的高校实验设备管理网站开发的全过程.     

从事放射性个人剂量监测分析与防护调查

为了能及时了解放射性工作人员的受照剂量，以便能够更好地保障放射工作人员的健康与安全，采用热释光测量法对包头地区从事放射性工作的工作人员进行了个人剂量监测，并对他们的剂量当量频数分布进行了统计与分析，对工作环境的防护进行了调查对比，就今后的工作提出建议。     

控轧技术在H型钢生产中的应用

根据钢板的控轧经验，结合H型钢轧制的特点分析控轧在轧制中运用的具体问题，制定H型钢控轧工艺方案。介绍了实际应用情况，并提出改进的措施。     

Model of Primary Austenite Dendrite Structure in Hypoeutectic Cast Iron

Ｉｔｗａｓｒｅｐｏｒｔｅｄ[1] ｔｈａｔｔｈｅｍｉｃｒｏ ｓｔｅｒｅｏｓｔｒｕｃｔｕｒｅｏｆｐｒｉｍａｒｙａｕｓｔｅｎｉｔｅｉｎｃａｓｔｉｒｏｎｃｏｎｓｉｓｔｓｏｆｐｒｉｍａｒｙｓｔｅｍｓａｎｄｓｅｃｏｎｄａｒｙａｒｍｓｔｈａｔ ｇｒｏｗａｃｃｏｒｄｉｎｇｔｏｄｅｎｄｒｉｔｅｃｒｙｓｔａｌｓｂｒａｎｃｈｒｕｌｅ ,ａｎｄｓｏｍｅｏｆｐｒｉｍａｒｙａｕｓｔｅｎｉｔｅｅｖｅｎｈａｖｅｔｈｉｒｄａｒｍｓ .ＭｉｙａｋｅＨｅｔａｌ[2 ]ｐｒｏｐｏｓｅｄａｃｏｎｃｅｐｔｏｆｒｅｇｉｏｎｍｏｄｅｌｂｙｓｔｕｄｙｉｎｇ…     

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine as a substrate of cytochrome P450 2D6: allosteric effects of NADPH-cytochrome P450 reductase

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), a neurotoxin that produces Parkinsonism symptoms in man, has been examined as a substrate of recombinant human cytochrome P450 2D6. When cumene hydroperoxide is used as an oxygen and electron donor, a single product is formed, identified as 4-phenyl-1,2,3,6-tetrahydropyridine. The K(m) for formation of this product (130 microM) is in agreement with the dissociation constants for MPTP binding to the enzyme determined by optical and nuclear magnetic resonance (NMR) spectroscopy. When the reaction is carried out with nicotinamide adenine dinucleotide phosphate (reduced) (NADPH) and recombinant human NADPH-cytochrome P450 reductase, a second product, identified as 1-methyl-4-(4'-hydroxyphenyl)-1,2,3,6-tetrahydropyridine, is formed in addition to 4-phenyl-1,2,3,6-tetrahydropyridine. The K(m) values for formation of these two products are 19 microM and 120 microM, respectively. Paramagnetic relaxation experiments have been used to measure distances between the protons of bound MPTP and the heme iron, and these have been used to construct models for the position and orientation of MPTP in the active site. For the cytochrome alone, a single mode of binding was observed, with the N-methyl close to the heme iron in a position appropriate for the observed N-demethylation reaction. In the presence of the reductase, the data were not consistent with a single mode of binding but could be explained by the existence of two alternative orientations of MPTP in the active site. One of these, characterized by a dissociation constant of 150 microM, is essentially identical to that observed in the absence of the reductase. In the second, which has a K(d) of 25 microM, the MPTP is oriented so that the aromatic ring is close to the heme iron, in a position appropriate for p-hydroxylation leading to the formation of the product seen only in the presence of the reductase. In the case of codeine, another substrate for cytochrome P450 2D6, the addition of reductase had no effect on the nature of the product formed, the dissociation constant, or the orientation in the binding site. These observations show that NADPH-cytochrome P450 reductase has an allosteric effect on the active site of cytochrome P450 2D6 that affects the binding of some substrates but not others.     

油砂地层中子-伽玛能谱Monte-Carlo模拟

本工作应用自行研制开发的中子 伽玛能谱测井的中子 伽玛射线随空间、能量、时间分布的蒙特卡罗模拟软件包计算了裸眼井、井眼里无下井仪器、油饱和砂岩地层、井眼注油条件下沿井轴和井壁的中子 伽玛射线随能量、时间分布及沿井轴和沿井壁的中子 伽玛射线能谱 ,研究了源距对中子 伽玛射线随能量、时间分布以及井轴与井壁中子 伽玛射线能谱的影响。     

超薄SiO2层的热生长

隧道小孔中超薄ＳｉＯ２的生长是ＥＥＰＲＯＭ电路制造的关键工艺之一。采用ＳＵＰＲＥＭ－Ⅲ工艺模拟程序对超薄ＳｉＯ２的热生长进行了工艺模拟，经过大量的工艺实验及优化，确定了超薄ＳｉＯ２的最佳生长条件，生长出的ＳｉＯ２性能良好，完全可满足ＥＥＰＲＯＭ研制的要求。     

HTR-10燃料元件装卸系统冷态调试

10MW高温气冷实验堆（HTR－10）是一座球床堆，由燃料元件装卸系统实现燃料元件的装卸和循环，且不需要停堆，为保证HTR－10的正常运行，燃料元件装卸系统必须安全，可靠，为此，必须对燃料元件装卸系统进行周密，细致的调试试验和验证，本文介绍了燃料元件装卸系统冷调试的主要调试项目，调试方法和调试结果。