环境镉致肾损伤与槲皮素应用时间的研究

实验研究了镉致急性肾损伤及槲皮素对肾损伤的保护作用.将雄性Wistar大鼠随机分成对照组、镉组、槲皮素治疗组,分别对各组大鼠进行生理盐水注射、氯化镉注射、氯化镉注射加槲皮素灌胃,然后测定镉致肾损伤指标:尿蛋白含量、血尿素氮(BUN)、尿乙酰氨基葡糖苷酶(NAG)、尿γ-L-谷氨酰转肽酶(γ-GT)、尿金属硫蛋白(UMT).研究结果表明:镉组与对照组相比,肾损伤指标含量显著增高;槲皮素治疗组与镉组相比,肾损伤指标含量显著降低,且随着应用槲皮素时间的增加,肾损伤指标含量逐渐恢复.因此,镉能够导致肾损伤,而槲皮素对镉致大鼠急性肾损伤具有保护作用,且其保护作用具有时间依赖性.     

求解背包问题的病毒协同进化粒子群算法

为提高粒子群算法的搜索性能,提出一种基于病毒进化理论的改进离散粒子群算法:病毒协同进化粒子群算法.在粒子群中引入生物病毒机制和宿主与病毒基于感染操作的思想,病毒采用与粒子等长的编码方式,执行反向代换、结合等操作,利用病毒的水平感染和垂直传播能力较好地维持个体的多样性和对解空间的局部搜索能力.通过解决背包问题对算法进行验证,仿真表明所提算法搜索性能优于遗传算法、模拟退火及标准粒子群等其他算法.该算法能有效求解背包问题等NP难题.     

MA制备GdSiGeDy合金系室温磁制冷性能研究

机械合金化(MA)是一种材料固态非平衡加工新技术.本文主要探讨稀土元素Dy在机械合金化工艺条件下对磁制冷合金GdSiGe磁熵变的影响,发现用机械合金化制备的GdSiGeDy合金系室温磁制冷材料不仅有光滑的磁熵变曲线,而且研究表明,由于元素Dy的加入在磁熵变达到单质Gd的两倍情况下大量减少使用昂贵元素Ge的结果,具有明显经济效益.     

双洞口配筋砌块砌体框支墙梁试验

为研究双洞口配筋砌块砌体框支墙梁地震前后的受力模式,在拟动力子试验前后进行了底层框架配筋砌块短肢砌体剪力墙结构三层足尺模型的竖向力静载试验.试验结果表明:托梁与上部墙体表现出良好的协同工作能力,其工作模式为拉杆拱.通过对其在拟动力试验前后的受力模式进行了比较,可知带洞口配筋砌块砌体框支墙梁结构体系在墙体受到一定损伤时,并不会使墙梁的受力机理发生明显改变.     

CFRP加固钢筋混凝土梁滞后应变计算方法

为了系统研究从零负载状态到满负载状态各个阶段CFRP片材加固梁滞后应变的计算方法,在充分考虑加固梁不同负载状态及受压区混凝土非线性本构关系的基础上,分别建立了不同负载贴片加固梁考虑混凝土抗拉作用时的滞后应变计算公式及不考虑混凝土抗拉作用时的简化计算公式.试验数据和对比分析结果表明:"考虑混凝土抗拉作用"公式的计算结果与试验数据吻合良好,计算误差<8%,明显优于现有文献的计算方法;"不考虑受拉区混凝土抗拉作用"公式的计算结果在混凝土开裂前和试验值相差较大,但对已裂加固梁的计算误差与"考虑混凝土抗拉作用"公式的计算误差接近.为简化计算,对未裂和已裂混凝土梁贴片加固时的滞后应变可分别采用"换算截面"公式和"不考虑混凝土抗拉作用"公式进行计算,两种简化方法的误差均不会超过10%.     

厌氧活性污泥PCR-DGGE图谱的优化

针对特种污泥PCR-DGGE图谱的优化一直是微生物分子生态学研究的重点.在反硝化抑制硫酸盐还原菌的研究中,研究厌氧硫酸盐还原污泥和反硝化污泥DNA的提取方法,应用通用引物958F/1401R扩增16S rDNA序列,探讨不同的退火温度对DGGE指纹图谱多样性影响,同时采用时间进程法对DGGE图谱进行优化.结果表明,采用PBS洗涤污泥和超声震荡有利于硫酸盐还原污泥DNA提取;采用958F/1401R为引物时,扩增片段大约500 bp,不同的退火温度对DGGE指纹图谱的多样性影响不显著;采用时间进程法可以很好地再现不同电泳阶段对样品的分离效果,最佳变性剂梯度为40%～60%,在130 V电压下,最佳电泳时间为5 h.     

S-P混杂纤维对混凝土长期性能与耐久性影响

采用对比的试验方法,研究并讨论了钢纤维、聚丙烯纤维及其混杂对混凝土长期性能及耐久性的影响.研究结果表明,用不同尺度、不同性质的钢纤维与聚丙烯纤维按二元混杂以总体积率0.9%掺入高性能混凝土中,明显改善了水泥混凝土的长期性能,90d干缩值减少36.6%,200d徐变度降低45.4%,并可显著提高混凝土的耐久性能,相对渗透系数降低79.03%,氯离子渗透系数降低30.5%.     

Set methods of left-turn waiting zone at signalized intersection

To maximize the number of vehicles passing by the stop-line in a cycle and improve the operation efficiency of intersection in China,the settlement of left-turn lane waiting-zone is becoming prevailing. Based on conflicting-point method,the internal mechanism of left-turn flow after stopping line was analyzed through taking postposition left-turn lane waiting-zone intersection for instance. The relationship between the first left-turn vehicle and the last vehicle of previous phase passing the conflicting point was expounded. According to the time of successive arriving of two vehicle flows at conflicting-point,the reasonable layout for waiting area of left-turn vehicles was researched when the clearance index was less than 0. The results suggest that the appropriate layout for waiting area of left-turning vehicles can improve the operation efficiency of intersections.     

An improvement to the simulation of phase-change heat-transfer during soil freezing and thawing

A new variable time step method, which is called the backwards calculating time step method, is presented in this paper. It allows numerical simulation of soil freezing and thawing while avoiding "phase change missing and overflowing". A sensitive heat capacity model is introduced through which the calculation errors are analyzed. Then the equation using the self-adjusted time step is presented and solved using finite differences. Through this equation, the time needed for a space cell to reach the phase change point temperature is calculated. Using this time allows the time step to be adjusted so that errors caused by "phase change missing and overflowing" are successfully eliminated. Above all, the obvious features of this method are an accelerated rate for adjusting the time step and simplifing the computations. An actual example proves that this method can accurately calculate the temperature fields during soil freezing and thawing. It is an improvement over traditional methods and can be widely used on com- plicated multi-dimensional phase change problems.