计算机图形学和模式识别在定量药物设计中的应用

一、引言本文简要介绍定量药物设计的概念及计算机图形学和模式识别在定量药物设计中的典型应用,并介绍了一个基于计算机图形学和模式识别的辅助药物设计系统。最后将指出它们的应用前景及有待解决的一些问题。     

一起220 kV变压器局部放电试验异常情况分析

对一起220 kV变压器现场局部放电测试结果进行分析,采用多端子校正-多端子测量的方法对变压器局部放电位置初步定位,结合变压器高压绕组局部放电表征参数进一步分析,最终确定油中气泡放电为变压器局部放电测试结果异常的原因,提出了现场处理方案,并对江苏地区冬季安装变压器的流程提出建议.     

略论上市公司反收购的法律规制

我国虽有多个法律部门对上市公司收购进行调整，但均未对反收购措施加以规范。文章介绍了美国、英国和欧盟对反收购的法律规定，建议在我国增设反收购法律规定。     

油色谱在线监测装置常见故障分析

油色谱在线监测装置通过对变压器油中溶解气体的实时检测,实现对变压器早期潜伏性故障的准确评估,其效果已在电网系统内得到充分肯定。但是在应用过程中,在线监测装置本身故障情况也越发频繁。首先简述了目前市面上主流的油色谱在线监测装置测试原理,分析常见的故障类型,并结合几起油色谱在线监测装置现场缺陷案例,阐述装置目前存在的一些问题。最后从保障变压器稳定运行的角度对在线监测装置提出运行维护建议。     

“一村一警”筑牢农村防火墙

10月30日上午,随着广西壮族自治区合山市公安消防大队4名干部挂职辖区派出所任副所长,专职消防工作,标志着该地区实行“一村一警”消防专项治理措施向纵深推进。     

异号权重模板CNN的似细化特性及其应用

本文发现并以定理的形式证明了具有异号权重模板的细胞神经网络系统在非均匀增益分段性输函数下的细 化稳态性性。     

掺杂光敏物质用于降低火工药剂激光发火阈值研究进展

在激光火工品研究领域,掺杂光敏物质是降低火工药剂发火阈值的核心技术之一。主要围绕近年来激光点火/起爆药剂研究中的光敏物质,包括炭黑、碳纳米管、氧化石墨烯、近红外吸收染料、金属纳米颗粒,梳理了各自的结构与光学特性之间的构效关系,归纳总结了掺杂光敏物质在火工药剂中用于激光点火研究取得的重要进展,分析了掺杂浓度、掺杂方式对发火性能影响的基本规律。通过对比发火阈值获得了光敏效果的初步排序,即以金纳米棒为首的金属纳米颗粒的光敏效果最佳,炭黑、碳纳米管、碳纳米粉、近红外吸收染料相继次之,并且建议未来需加强激光点火和材料研究领域交叉融合,提高研究系统性、普适性、可比性。     

INVESTIGATION ON THE COMPUTATIONAL PROPERTIES OF INTRANEURONAL DYNAMICS

This paper aims at exploring computational properties of dynamic processes in neu-ral systems,studying their mathematical formulation,and applying the results to artificial neuralnetwork modeling.The stimulus-response processes in neurons are first introduced briefly,thenproperties of neurons described by the Hodgkin-Huxley equations are analyzed.After studyinghow to simplify,the Hodgkin-Huxley equations while maintaining its properties,the concept of dy-namic neuron model is proposed.It is pointed out that the neuron model should include internalstates in order to obtain time-variant thresholds,such as refractory periods of neurons.Finallywe discuss problems related to neural network models based on pulse-stream communication andthe contribution of intraneuronal dynamics to collective properties of the neural network.     

Synthesis, characterization and antitumor activity of rare earth （Y, La） substituted phosphotungstates containing 5-fluorouracil

Two rare earth substituted Keggin-type phosphotungstates containing 5-fluorouracil,K10C4H4FN2O2Y(PW11O39)2·10H2O(FYPW) and K9(C4H4FN2O2)2La(PW11O39)2·18H2O(FLaPW)were synthesized in aqueous solution,and the structures were characterized by Fourier transform infrared spectroscopy(FT-IR),element analysis,inductively coupled plasma spectrometry(ICP),X-ray powder diffraction(XRD) and 1 H nuclear magnetic resonance(NMR).Thermal analysis showed that the decomposition processes of the two compounds could be divided into three steps,the loss of crystal water,the decomposition of 5-fluorouracil unit and the decomposition of Keggin-type polyanions. The in vitro cytotoxicities against HEK 293,HeLa and HepG-2 cells were studied by methyl thiazolyl tetrazolium(MTT)assay.The results showed that FYPW and FLaPW had higher antitumor activities than 5-fluorouracil,C4H4FN2O2H2PW12O40·8H2O and rare earth substituted polyoxometalates K11Ln(PW11O39)2·nH2O(Ln=Y,La).It was concluded that introducing 5-fluorouracil and rare earth(Y or La)into its structure was a considerable way to enhance antitumor activities of polyoxometalates.     

长城微机仿真日立T-560/20终端及GW560汉字仿真软件

长城微机仿真日立T-560/20终端及GW560汉字仿真软件,是由中国长城计算机集团公司和日立公司及日本INTER COM公司合作开发成功的,用国产化的长城系列机仿真日立M和L系列配置的T-560终端功能,可近程或远程连接日立主机系统,极其方便地在长城微机上实现各种联机操作,如数据资料查询、提取信息、资料录入、文件传输及程序的相互开发等。