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931.
G García-Bermúdez H Somacal MA Cardona A Filevich E Achterberg L Szybisz 《Canadian Metallurgical Quarterly》1995,51(3):1181-1191
932.
933.
T P?usa P Górski H Frank-Piskorska M Kowalski J Kruszewski P Kuna M Kurek R Kurzawa W Silny E Zawisza 《Canadian Metallurgical Quarterly》1996,1(4):292-293
A review of isolates of Neisseria meningitidis and other laboratory evidence of meningococcal infection was carried out for the period 1990-1995. Thirty-three patients with evidence of meningococcal disease were identified over the six year period. Group B organisms were the most commonly identified, but an increase in Group C has occurred and is almost equal in number. Data from clinical, laboratory and public health sources should be centralized in a National Surveillance Centre. 相似文献
934.
JP Larsen H Odegaard E Tandberg A H?dneb? D Aarsland 《Canadian Metallurgical Quarterly》1996,9(4):157-163
As hypersensitivity to natural rubber latex (NRL) has become an increasingly recognized problem in children, identification of all groups at risk seems important. In this study hypersensitivity to NRL was evaluated in 337 children with potential risk factors. We identified by questionnaire children's underlying diseases, history of surgical procedures, evidence of atopy and patient's history of NRL-specific reactions. Hypersensitivity to NRL and other allergens relevant in the Düsseldorf area was evaluated by skin prick test and specific IgE. In 9.2% of all children hypersensitivity to NRL was observed. Significant risk factors for hypersensitivity to NRL were, among the underlying diseases, spina bifida (odds ratio 29.2), hydrocephalus internus (10.1), gastrointestinal malformation (5.2) and atopy (2.2). Surgical procedures with significant risk were the implantation of a ventriculo-peritoneal shunt (15.7) and surgery of the gastrointestinal tract (3.1). Frequency of surgical procedures correlated (p < 0.001) with risk of hypersensitivity. Frequent surgery and atopy were found to have an additional effect on the risk of hypersensitivity. Information about previous NRL-specific reactions obtained by questionnaire was of little predictive value when performing multivariate analysis. For children at high risk for hypersensitivity to NRL preoperative evaluation and, in case of hypersensitivity, preventive measures seem to be advised. 相似文献
935.
R Bookstein W Demers R Gregory D Maneval J Park K Wills 《Canadian Metallurgical Quarterly》1996,23(1):66-77
Tumor suppressor genes such as p53 contribute to the oncogenic process via loss-of-function mechanisms such as genetic mutation or complex formation with other cellular or viral proteins. p53 is mutated in approximately 50% of human tumors and has an important role in the genesis or progression of both colorectal and hepatocellular cancers. Colorectal cancer is leading cause of cancer mortality in the United States, whereas hepatocellular cancer is the leading worldwide cause of cancer death; the liver is a primary site of morbidity in both diseases. Because systemic tumor suppressor gene therapy is currently not feasible, we have chosen to develop a regional form of such therapy directed at primary or metastatic liver neoplasms. Gene replacement therapy with p53 is a promising new strategy to treat advanced human cancers. 相似文献
936.
937.
938.
M. A. Lotonov 《Measurement Techniques》1996,39(11):1083-1091
It is proved that biased estimates of parameters are always more effective than unbiased estimates in the case of asymmetric
distribution laws of random quantities. Expressions are obtained for the root mean square deviation of a biased estimate of
a parameter from its value for the cases of normal, Poisson, Rayleigh, and gamma distribution laws.
Translated from Izmeritel'naya Tekhnika No. 11, pp. 8–13, November, 1996. 相似文献
939.
A.G. Berkovski G. Chiodi J.-P. Fabre A. Frenkel S.V. Golovkin Yu.I. Gubanov G.N. Kislizkai E.N. Kozarenko I.E. Kreslo A.E. Kushnirenko G. Martellotti D. Mazza A.M. Medvedkov G. Penso 《Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment》1996,380(3):537-543
We present the performance of a high-speed gateable vacuum image pipeline, which permits individual images to be delayed and selected from continuous non-repetitive image stream. This device is composed of a vacuum tube equipped with a photocathode at one end, a phosphor screen at the other end, and a system of metal grids in between. Photoelectrons produced by the images focused on the photocathode, are guided by a uniform magnetic field, parallel to the tube axis. By changing the grid potentials, the drift time of the photoelectrons inside the tube can be varied from 0.35 to 1.5 μs. An image can then be selected by an external trigger with a time resolution in the range of 4–30 ns, depending on the delay time. The selected photoelectrons are finally accelerated onto the phosphor screen, set at 10 kV, where they reproduce the desired image. With a magnetic field of 0.1 T, a spatial resolution of 33 lp/mm was obtained. The high spatial and time resolution make this device an interesting tool for high-energy physics and astrophysics experiments, and for high-speed photography. 相似文献
940.
This article describes the phenomenon of morphological instability in solid-solid phase transformations during thin-film interdiffusion,
specifically related to the initial stages of precipitation when phase growth occurs along the interface between thin films.
The experimental observations that revealed this effect will be presented, and a working hypothesis will be discussed. Experimental
observations suggest that the ledge mechanism of growth is present in this system but does not inhibit the formation of interfacial
instabilities. It is proposed that morphological stability for solid-phase growth occurring during thin-film interdiffusion
can be treated by the inclusion of a solute-source term into the two-dimensional perturbation approach generally used to study
unstable growth morphologies. Experimental observations that provide qualitative and semiquantitative support for the solute-source
model are also presented. 相似文献