Self-ignition and combustion of a water-fuel emulsion during its injection into heated air. II. Ignition delay time of M-40 fuel oil

We studied experimentally the influence of the degree of water emulsification ofM-40 mazut heated to the water boiling point on the self-ignition time with its pulsed high-pressure injection into heated air. It is shown that water addition does not change the chemistry of the reaction and heating the water-fuel emulsion leads to the disappearance of differences in the ignition character of the emulsion and the moisture-free fuel. It is confirmed that the features of selfignition are determined mostly by conditions of mixture formation. Indirect evidence is obtained that the dynamic tensile strength of the fluid strongly influences the primary dispersion of the jet during its outflow from the sprayer nozzle.Institute of Theoretical and Applied Mechanics, Novosibirsk 630090. Translated from Fizika Goreniya i Vzryva, Vol. 31, No. 4, pp. 20–25, July–August, 1995.     

Generation of chromosome fragment specific bovine DNA sequences by microdissection and DOP-PCR

Trends in causative organisms and sources of infection were studied in a series of 288 episodes of bacteremia in neutropenic cancer patients observed in a single institution from 1986 to 1993. The incidence of bacteremia increased significantly from 20 episodes per 1000 admissions in 1986 to 50 episodes per 1000 admissions in 1993 (p = 0.00001). Over the study period, a continuous increment in gram-positive bacteremia, which reached 81% of episodes in 1993 (p = 0.000001), was observed. Conversely, the incidence of gram-negative bacteremia remained stable. Coagulase-negative staphylococci and viridans group streptococci were the most commonly isolated pathogens. Bacteremia caused by coagulase-negative staphylococci increased from 3 episodes per 1000 admissions to 19 episodes per 1000 admissions (p = 0.0001), and viridans group streptococci bacteremia increased from 0 episodes per 1000 admissions to 19 episodes per 1000 admissions (p = 0.000001). The upward trend in gram-positive bacteremia appeared to be related to a significant increase in both intravascular catheters (p = 0.003) and oral mucositis (p = 0.003) as sources of infection. Specific strategies to prevent chemotherapy-induced mucositis and catheter-related bacteremia merit further investigations.     

Transmit permission control on spread ALOHA packets in LEOsatellite systems

A transmit permission control method for improving the throughput characteristics of a low Earth orbit (LEO) satellite communication system employing spread-slotted ALOHA multiple-access scheme is proposed. Both nonfading and fading satellite links are considered. The basic idea of the proposed scheme is to decrease the level of interference at each satellite and, hence, to increase the probability of packet success, by prohibiting the packet transmission from the users with relatively high propagation loss to their connecting satellites. It is shown that the method has the ability to improve the throughput performance in heavy traffic loads and the peak value of the throughput, significantly. It is also shown that the average delay performance of the system employing the proposed scheme is superior to that of the conventional system at heavy traffic loads     

The effect of bandwidth allocation policies on delay inunidirectional bus networks

We consider the problem of allocating bandwidth fairly to each node in a shared, unidirectional bus network. We focus on the p_i persistent protocol, since these are open loop policies designed to operate well in high speed networks, which have a very large bandwidth-delay product and feedback in the upstream direction is not available in a timely manner. First, we introduce an improvement to the basic p_i persistent protocol, in which we replace random coin tosses with a deterministic counting algorithm, and thereby reduce the delays for all nodes for any given choice of {p_i}. We then describe an exact method for calculating average packet delays and queue lengths in both the p_i persistent and our new deterministic n out of m protocols, based on the regenerative approach of Georgiades et al. (1987). These delay results, together with simulation measurements, show that both of these protocols still waste some bandwidth. After presenting a lower bounding argument to show that some wasted bandwidth is inevitable in all such distributed access control schemes, assuming a passive bus without feedback in the upstream direction, we show that changing the bus to unidirectional point-to-point links between (very simple) active interfaces at each node allows us to construct distributed access schemes that require no upstream feedback and are both work conserving and fair. To illustrate how this can be done, we introduce the p_i preemptive protocol, in which each node randomly inserts its own packets into the traffic arriving from upstream. We derive a simple and effective heuristic for calculating the preemption probability for each node, and use simulation to show how well it equalizes the delays at each node     

Effects of single doses of irradiation on the expression of resistance-related proteins in murine NIH 3T3 and human lung carcinoma cells

In this report the effects of single doses of ionizing radiation on the mRNA expression of several proteins involved in multiple drug resistance were analyzed. Murine NIH 3T3 cells treated with single doses of 5, 10 and 20 Gy during the time interval from 1.5 to 72 h after irradiation were compared with their corresponding controls at the same points of time. The glutathione S-transferase-pi (GST pi) level was elevated in cells treated with 10 or 20 Gy from 24 to 72 h after irradiation compared with the control. Topoisomerase II alpha and thymidylate synthase were decreased in irradiated cells 24-72 h after exposure. These down-regulations were associated with cellular proliferation, determined by mRNA expression of the proliferation marker histone 3. Irradiated cells exhibited no alteration in the P-glycoprotein or glutathione peroxidase mRNA content. The finding that GST pi mRNA was overexpressed after irradiation was validated by investigations on a human lung carcinoma cell line (LXF 289) on the mRNA and protein level. Thus, our results indicate that irradiation alters the expression of proteins involved in multidrug resistance and may, therefore, play a role in clinical drug response.     

c-KIT expression enhances the leukemogenic potential of 32D cells

The growth of human leukemic cells in culture and in vivo is dependent upon the presence of hematopoietic growth factors. Most populations of human leukemic acute myeloblastic leukemia (AML) cells express c-Kit on their surface and respond to Kit ligand (KL) in culture. To determine if this interaction was of potential significance in vivo we used a mouse model system. 32D cells, a murine IL-3-dependent myeloid cell line, were rendered KL responsive by transfection of the murine c-Kit. After injection of 32D or 32D-Kit cells into syngeneic hosts, animals bearing 32D-Kit cells, but not 32D cells, became moribund and were killed. These animals had circulating leukemic blast cells, infiltration of bone marrow, spleen, brain, liver, lung, and kidney. Cells recovered from some of the animals continued to be dependent upon IL-3 or KL for growth while in other cases the cells were factor independent. This model illustrates that the constitutive expression of c-Kit enhances the leukemic potential of 32D cells. The model will be useful for studying the progression of leukemia in vivo and testing whether interruption of the interaction of Kit and KL can affect the growth of leukemic cells.     

Transient and dynamic average-value modeling of synchronous machinefed load-commutated converters

A new average-value model of a synchronous machine fed load-commutated converter is set forth in which the stator dynamics are combined with the DC link dynamics. This model is shown to he extremely accurate in predicting system transients and in predicting frequency-domain characteristics such as the impedance looking into the synchronous machine fed load-commutated converter. The model is verified against a detailed computer simulation and against a hardware test system, thus providing a three-way comparison. The proposed model is shown to be much more accurate than models in which the stator dynamics are neglected     

Useful NMR solvent mixture for polyesters: Trifluoroacetic acid-d/chloroform-d

Summary NMR spectra of high molecular weight polyesters such as polyglycolide (PG) and poly(ethylene terephthalate) (PET) have not been available because of low solubility in suitable NMR solvents. Although PG is not soluble enough at ambient temperatures for NMR spectra in either chloroform-d or trifluoroacetic acid-d alone, it dissolves readily to over 0.9% in a mixture of the two. At this concentration, ¹H and ¹³C spectra can be obtained on samples where end group signals are visible from which molecular weights can readily be determined. The solutions are stable up to at least four days when moisture is excluded. NMR spectra of PET can likewise be obtained at ambient temperatures in the solvent mixture which dissolves up to at least 0.6% of PET.     

Movement stability analysis of a pipe string in a thixotropic fluid

Features of movement of a drill pipe string in a well filled with a thixotropic fluid are analyzed taking into account inertial and elastic forces of the rope system. It is shown that processes of fluid structure degradation can lead to nonstationary movement of the pipes. In this case periodic and chaotic auto-oscillations are excited in the system.Bashkir State University, Ufa, Russia. Translated from Inzhenerno-Fizicheskii Zhurnal, Vol. 66, No. 4, pp. 405–411, April, 1994.