MRT of experimental liver abscesses: a comparison of a new blood pool contrast medium with gadolinium-DTPA in animal experiments

PURPOSE: In an experimental pyogenic liver abscess model, the signal intensities were compared intraindividually and interindividually after the application of a new blood pool contrast agent, 24-gadolinium-DTPA (diethylenetriamine-pentaacetic acid) cascade polymer, and after the application of gadopentetate dimeglumine. METHODS: In 20 rabbits with experimentally induced liver abscesses, the relative signal intensities of the liver, abscess centre, abscess wall and portal vein were assessed before and between 30 seconds and 60 minutes after injection of a 25 mumol/kg dose of gadolinium polymer and of 100 mumol/kg of gadolinium-DTPA, respectively. Measurements were performed at 1.5 Tesla, using a head coil and a Flash-2-D sequence. RESULTS: The interindividual comparison (unpaired T-test, p < 0.05) yielded significant differences of the relative signal intensities of the abscess centre (at any time point after contrast-media application), abscess wall (between 15 and 60 minutes after contrast media application), and portal vein (between 30 seconds and 7.5 minutes after contrast media application). The interindividual comparison showed a significantly higher abscess centre-liver contrast (between 30 seconds and 12.5 minutes after contrast media application) and a significantly higher abscess wall-centre contrast (between two and 7.5 minutes after contrast media application) after the application of gadolinium polymer compared with gadopentetate dimeglumine. CONCLUSION: In this animal model, the higher abscess centre-liver contrast after the application of gadolinium polymer was the basis for a better and prolonged visibility of the abscesses, as compared with images acquired after injection of gadopentetate dimeglumine.     

Interactions in compatible polymer systems

Summary Dynamic mechanical measurements on polystyrene — poly(vinylmethylether) blends are demonstrating that the relaxation processes in the blends are mainly connected with the motions of the poly(vinylmethylether) chain.Concerning the effect of mixing on topological properties of the blends, an increase of the polydispersity of the relaxation processes is detected in blends with high molecular weight polystyrene while low molecular weight polystyrene exerts an effect of dilution upon the relaxation of the high molecular poly(vinylmethylether) chains.From these measurements as well as from thermoanalytical data it results that the energetic interaction is more pronounced in the blends with oligomeric than with high molecular weight polystyrene. The glass transition temperature shows a larger deviation from additivity for blends with high molecular polystyrene than for those with oligomeric polystyrene.Herrn Prof. Dr. M. Kryszewski zum 60. Geburtstag herzlichst gewidmet     

Natrium-Aluminium-Silicate - Eigenschaften und Anwendungen

Sodium Aluminium Silicates - Properties and Application Sodium aluminium silicates in amorphous and crystalline form are used since many years in various technical processes. The crystalline sodium aluminium silicates, e. g. zeolites, belong to the group of structured silicates and are known for their reversible water uptake and alkaline earth exchange properties. Recently, sodium aluminium silicates have gained considerable importance since their cation exchanging ability can be utilized in washing agents for the removal of undesirable hardness of water. Thus, the polyphosphates used in washing agents can possibly be substituted. Zeolites can be supplied to the detergent industry in the form of powder or suspension. Production of the powder by spray drying does not involve special problems. Incorporation of the powder into the slurry of the detergent appears to be an anachronism from the viewpoint of energy saving. Optimization work on suspensions of zeolite yielded stable products with 45 to 48% zeolite content. The theory of critical particle concentration was applied in this work.     

Numerical simulation of non-linear chatter vibration in turning

In this paper, basic relationships and algorithms for numerical simulation of non-linear, self-excited vibrations in single degree-of-freedom cutting systems are presented. Non-linearities due to the tool leaving the cut, as well as interference between the cutting tool clearance face and cutting surface waviness, were taken into consideration. Examples of vibration simulation results are shown.     

What if computers could think?

The question whether or not computers can think was first asked in print by Alan Turing in his seminal 1950 article. In order to avoid defining what a computer is or what thinking is, Turing resorts to the imitation game which is a test that allows us to determine whether or not a machine can think. That is, if an interrogator is unable to tell whether responses to his questions come from a human being or from a machine, the machine is imitating a human being so well that it has to be acknowledged that these responses result from its thinking. However, then as now, it is not an indisputable claim that machines could think, and an unceasing stream of papers discussing the validity of the test proves this point. There are many arguments in favour of, as well as against, the claims borne by the test, and Turing himself discusses some of them. In his view, there are mice possible objections to the concept of a thinking machine, which he eventually dismisses as weak, irrelevant, or plain false. However, as he admits, he can present no very convincing arguments of a positive nature to support my views. If I had I should not have taken such pains to point out the fallacies in contrary views.     

The UK Cleanfeed system — Lessons for the German debate?

As readers of this journal will of course know, the Zugangserschwerungsgesetz has caused considerable and often very profound debate in Germany about the limits of legal and technological interference with the freedom of access to information, culminating in the temporary refusal of the President to sign the law into action. In the UK by contrast, a core aspect of this law, the technical prevention of access to sites hosting illegal content by ISPs, was introduced through the so called “Cleanfeed system” as early as 1996, with little or no public debate, and bypassing by and large all parliamentary procedure and scrutiny. This article has a threefold aim: First, it gives a brief account of the history and implementation of the UK Cleanfeed system1; second, it explains some of its more unusual aspects by putting them into the historical and constitutional context of policing in the UK, and third, it highlights those experiences made with the system that are of direct relevance for the German discussion.