Surfactant-Controlled and Microwave-Assisted Synthesis of Highly Active Ce x Zr1−x O2 Nano-Oxides for CO Oxidation

Uniform nanosized, mesoporous and high specific surface area ceria–zirconia (1:1 mole ratio) solid solutions were synthesized employing a poly-block copolymer surfactant combined with microwave or thermal treatment. For comparison purpose an identical composition Ce _x Zr_1?x O₂ mixed oxide was also prepared by a conventional coprecipitation method. The surface and bulk structure of the synthesized samples were investigated using X-ray diffraction (XRD), small angle X-ray scattering (SAXS), Raman spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), BET surface area and BJH pore size distribution (PSD) methods. The catalytic activity was evaluated for CO oxidation at normal atmospheric pressure. The Ce _x Zr_1?x O₂ solid solutions obtained through surfactant use exhibited high specific surface area and mesoporosity. The XRD measurements revealed the presence of cubic Ce_0.75Zr_0.25O₂ and Ce_0.6Zr_0.4O₂ phases in the case of conventional coprecipitation and surfactant controlled synthesized samples, respectively. The Raman measurements revealed existence of more oxygen defects in the surfactant-controlled and microwave treated sample. The SEM images suggested that all samples consist of typical spherical agglomerates with almost uniform size within the nanometer size range. The TEM measurements revealed nanosized crystallites in a narrow range between 4 and 8 nm, and densely packed in the case of conventional precipitation and microwave treated samples. Interestingly, the Ce _x Zr_1?x O₂ solid solution obtained by surfactant-controlled method and treated with microwave radiation exhibited better CO oxidation activity than other samples. Enhanced activity of surfactant-controlled and microwave treated sample is correlated with its unique physicochemical characteristics.     

MiR-199a-3p Induces Mesenchymal to Epithelial Transition of Keratinocytes by Targeting RAP2B

Cutaneous squamous cell carcinoma (CSCC) is an epidermal skin cancer that evolves from normal epidermis along several pre-malignant stages. Previously we found specific miRNAs alterations in each step along these stages. miR-199a-3p expression decreases at the transition to later stages. A crucial step for epithelial carcinoma cells to acquire invasive capacity is the disruption of cell–cell contacts and the gain of mesenchymal motile phenotype, a process known as epithelial-to-mesenchymal transition (EMT). This study aims to study the role of decreased expression of miR-199a-3p in keratinocytes’ EMT towards carcinogenesis. First, we measured miR-199a-3p in different stages of epidermal carcinogenesis. Then, we applied Photoactivatable Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation (PAR-CLIP) assay to search for possible biochemical targets of miR-199a-3p and verified that Ras-associated protein B2 (RAP2B) is a bona-fide target of miR-199a-3p. Next, we analyzed RAP2B expression, in CSCC biopsies. Last, we evaluated possible mechanisms leading to decreased miR-199a-3p expression. miR-199a-3p induces a mesenchymal to epithelial transition (MET) in CSSC cells. Many of the under-expressed genes in CSCC overexpressing miR-199a-3p, are possible targets of miR-199a-3p and play roles in EMT. RAP2B is a biochemical target of miR-199a-3p. Overexpression of miR-199a-3p in CSCC results in decreased phosphorylated focal adhesion kinase (FAK). In addition, inhibiting FAK phosphorylation inhibits EMT marker genes’ expression. In addition, we proved that DNA methylation is part of the mechanism by which miR-199a-3p expression is inhibited. However, it is not by the methylation of miR-199a putative promoter. These findings suggest that miR-199a-3p inhibits the EMT process by targeting RAP2B. Inhibitors of RAP2B or FAK may be effective therapeutic agents for CSCC.     

An auto-learning approach for network intrusion detection

In this paper, we propose a novel intrusion detection technique with a fully automatic attack signatures generation capability. The proposed approach exploits a honeypot traffic data analysis to build an attack scenarios database, used to detect potential intrusions. Furthermore, for an effective and efficient intrusion detection mechanism, we introduce several new or adapted algorithms for signature generation, signature comparison, etc. Finally, we use DARPA’99 and UNSW-NB15 traffic to evaluate the proposed approach. The results indicate that the generated attack signatures are of high quality with low rates of false negatives and false positives.     

Asymmetric Epoxidation of α,β-Unsaturated Ketones over Heterogenized Chiral Proline Diamide Complex Catalyst in the Solvent-Free Condition

Chiral copper proline diamide complex has been immobilized on surface of mesoporous silica. These heterogenized complex catalysts were examined as asymmetric catalysts for the epoxidation of α,β-unsaturated carbonyl compounds with hydrogen peroxide, tert-butyl hydroperoxide and urea hydroperoxide as the oxidants under solvent-free condition. Enantiomeric excesses of up to 84% can be achieved conveniently with a good conversion using these promising catalysts.     

2007显示周:系统和部件

从显示器的背光源到屏幕保护玻璃,以及处于二者之间的显示系统和器件部分的发展状况,是2007年显示周上重要的展出内容,本文即是这次展览的概述。     

Performance of a small‐scale compressed air storage (CAS)

The use of renewable energy, such as wind and solar, has significantly increased in the last decade. However, these renewable technologies have the limitation of being intermittent; thus, storing energy in the form of compressed air is a promising option. In compressed air energy storage (CAES), the electrical energy from the power network is transformed into a high‐pressure storage system through a compressor. Then, when the demand for electricity is high, the stored high‐pressure air is used to drive a turbine to generate electricity. The advantages of CAES are its high energy density and quality, and for being environmentally friendly process. In the existing facilities of University of Auckland, New Zealand, air cavern is not available; thus, a high‐pressure tank is used to store the compressed air, which could provide an excellent opportunity for small size applications. There is a limited literature available on the temperature and pressure profiles in a typical high‐pressure tank during charging and discharging processes. Therefore, this research investigates how temperature and pressure inside a high‐pressure tank change during charging and discharging processes. It will provide a better understanding for heat transfer in such system. Furthermore, it will provide the necessary information needed for the designing of an efficient small‐scale CAES. In this work, air is compressed to a maximum pressure of 200 bar and stored into a 2 L tank, which is fully fitted with a pressure transducer and a thermocouple suitable for high‐pressure measurements. The charging and discharging process is theoretically modeled, and the results are compared with the experimental measurements, showing a good agreement. The heat balance on the system is used to validate the steady‐state condition, while dynamic analysis is used to predict the transient change of compressed air and tank wall temperatures. The theoretical modeling is undertaken by solving the differential equations describing the transient change in temperature of both air and tank wall. The results of this study show that air temperature rises from 24°C to 60°C at 100 bar and from approximately 17°C to over 60°C at 200 bar. During discharging process, air temperature drops from ambient to 5°C at starting pressure of 100 bar and to ?20°C at starting pressure of 200 bar.     

Ten Million Fold Reduction of Live Bacteria by Bactericidal Filter Paper

An extremely efficient bactericidal filter paper is developed that is capable of removing 99.99999% of Escherichia coli bacteria in a simple filtration process. The novel approach utilizes two active bactericidal components: a bactericidal agent, triclosan, which acts synergistically with a cationic polyelectrolyte binder with antibacterial properties. The biocide is incorporated into the block copolymer micelles attached to the cellulose fibers via the cationic polyelectrolyte. As the water containing the bacteria is passed by gravity through the filter paper, the bactericidal agents are transferred to the bacteria through collisions with the micelles or coated fibers. A synergy between the biocide and the polyelectrolyte is responsible for the extremely high efficiency in deactivating the bacteria. The filtered water is free of biocide other than that transported by the dead bacteria. This technology represents a very simple approach to provide potable water under a wide range of primitive conditions.