Modification of coconut fibers with polyaniline for manufacture of pressure‐sensitive devices

This article studies the modification of coconut fibers with polyaniline (PAni) with help of statistical experimental design techniques. The main factors studied here were the techniques used for particle dispersion (sonication vs. magnetic stirring) and the type of initiator (ammonium persulfate, APS, vs. ammonium cerium sulfate dihydrate, Ce(IV)). The obtained materials were characterized through low field nuclear magnetic resonance, small‐and wide‐angle X‐ray scattering, scanning electron microscopy, fourier transform infrared spectroscopy, and ultraviolet–visible spectroscopy. Additionally, the electrical resistivities and respective sensitivities to variations of the applied pressure were evaluated for all obtained samples, with help of standard volume resistivity measurements and electro‐mechanical tests. The materials prepared through magnetic stirring with APS presented the best electrical and electromechanical properties, although materials prepared through sonication with Ce(IV) also presented good electrical and electromechanical properties and could be prepared much faster. As a consequence, modification of coconut fibers with PAni, using sonication as the particle dispersion technique and Ce(IV) as initiator, constitutes a very promising procedure for manufacture of pressure‐sensitive devices. POLYM. ENG. SCI., 54:2887–2895, 2014. © 2014 Society of Plastics Engineers     

An investigation on machinability assessment of Al-6XN and AISI 316 alloys: an assessment study of machining

This work presents machinability assessment of AL-6XN super austenitic stainless steel alloy. Cutting forces, surface roughness, work hardening tendency and tool wear were analyzed. The assessment was conducted based on a comparison between the AL-6XN alloy and the well-known alloy in the machining field AISI 316. Finite element analysis (FEA) study was also conducted and used in this assessment. Experimental results showed maximum increase of 70% and 57% in the feed and normal forces of the AL-6XN alloy, respectively. Maximum increase in the work hardening tendency of 59% was recorded for the AL-6XN alloy while only 29% was recorded for the 316 alloy. The roughness analysis recorded an increase of 186% for the AL-6XN alloy compared to the 316 alloy. Tool wear analysis revealed the build-up edge formation, severe chipping, flank and crater wear (CW) during cutting AL-6XN alloy whereas small chipping, flank and CW were noticed during cutting 316 alloy. FEA study showed when the AL-6XN alloy machined using 65 and 94?m/min cutting speeds, the increases (compared to the 316 alloy) were: 12% and 8% in plastic strain; 20% and 20% in stresses; 48% and 100% in residual tensile stresses; 22% and 92% in residual compressive stresses, respectively.     

Effects of Sc Addition and Direct Aging Treatment on Microstructure and Hardness of AlSi10Mg Alloy

Cu-mold centrifugal cast processing is employed as a rapid solidification method for producing samples with and without Sc. The Al–Si–Mg and Al–Si–Mg–Sc alloy samples are exposed to direct aging treatments varying temperature and time to verify the microstructural changes. Both rapidly solidified samples and as-aged samples are characterized by a number of methods, including optical microscopy, SEM–EDS, transmission Electron Microscopy (TEM)–EDS, TEM–HAADF, X-ray diffraction (XRD), differential scanning calorimetry (DSC), and Vickers hardness. At first, the results point to a strong precipitate-related hardening effect formed as a result of the Sc addition to the alloy. All samples containing Sc show a higher hardness value when compared to their respective treated samples without Sc. Second, when comparing the Al–10Si–Mg–0.4Sc alloy samples among themselves after being treated at different conditions, high temperatures, and excessive treatment times are recognized as detrimental to the hardness. This is due to the growth of larger Sc-bearing precipitates of approximately 1 μm in size under such conditions, having lower efficiency in pinning dislocations during loading. The best aging condition is 255 °C for 60 min, which produces a very fine dispersion of Mg and Sc intermetallics (200 nm in size) with a peak hardness of 110 HV.     

Molecular Docking Reveals the Binding Modes of Anticancer Alkylphospholipids and Lysophosphatidylcholine within the Catalytic Domain of Cytidine Triphosphate: Phosphocholine Cytidyltransferase

Alkylphospholipids are synthetic analogues of endogenous phosphatidylcholines with a remarkable ability: induce the selective apoptosis of exponentially growing tumor cells. One hypothesis concerning their mechanism of action is the inhibition of cytidine triphosphate:phosphocholine cytidyltransferase (CCT), which would significantly suppress the phosphatidylcholine biosynthesis to trigger apoptosis. Herein, homology modeling, docking simulations, and the analyses of molecular interaction fields are used to suggest the most probable binding modes of four alkylphospholipids (edelfosine, erucylphosphocholine, perifosine, and miltefosine) and lysophosphatidylcholine at the catalytic domain of human CCT. All compounds display bind modes in agreement with the corresponding groups found in the CCT substrate, phosphocholine, while their binding strengths are increased because of the interaction of the alkyl chains with hydrophobic residues from the M domain of the protein. Analyses of the geometry of the CCT binding‐site also suggest that small groups, such as benzyl/2‐phenylethyl ethers or equivalent heterocycles, could replace the O‐methyl group in edelfosine to yield even better inhibitors. It is believed this study can guide the development of new alkylphospholipids with an improved profile for the inhibition of phosphatidylcholine biosynthesis, a critical component for cell cycle progression that can be explored in cancer chemotherapy. Practical Applications: Studies focusing on the interactions between small ligands and their protein targets are decisive for the comprehension of how conformational changes in the macromolecular structure dictates the biological activity and, consequently, how they can be explored in drug discovery. Most of the current studies on alkylphospholipids focuses on their physicochemical interactions with cholesterol and sphingolipids in lipid rafts that, because of the variability and complexity of the membrane phases, hardly can provide structural data in the X‐ray crystallography assays necessary for molecular modeling studies. Therefore, by exploring the inhibition of human cytidine triphosphate:phosphocholine cytidyltransferase as an alternative and, probably, complementary hypothesis to the membrane rafts, a helpful strategy can be provided to overcome the clinical limitations of alkylphospholipids.     

Simulation of Grain Drying in Natural Convection Dryer

All the works so far on simulation of grain drying by natural convection of air presents conflicting reslts on the drying time forecast. In this work the models of Hukill, Thompson and Michigan are tested in same type of dryer. Appropriate equations are developed to correct the drying time, starting form the models of Thompson and Hukill. The solution of the equations of michigan model is developed on fintie difference and similarly and some speical technuques are utilized on the Thompson model. 53 test results are utilzed here to validate the simulation model of drying.     

Characterization of Physico-Chemical Properties of Oil/Water Systems: Interfacial Behavior Prediction

The tractability of petroleum is intimately related to the type of emulsion that is formed during its production. The characteristics of water/oil and oil/water emulsions depend on some factors such as the density and the composition of the oil. In this work, the properties of oils coming from the Campos Basin, Brazil, were evaluated by means of water-in-oil emulsion physico-chemical, interfacial, and characterization tests. Such properties have been correlated with the tractability of the petroleum in order to establish a behavior prediction method based on the properties of such petroleum. The main tool used in this work was the chemiometry technique. Through this method, it was possible to conclude that density, viscosity, surface tension, and nickel content were the properties that influenced the separation of the oils. Density, pour point, initial temperature of crystal formation (TIAC), characterization factor, and nitrogen content were the properties that influenced the diameter of the emulsion drops.     

过程自动化实习培训装置的设计制造

介绍了一种实习培训装置，该装置新型、实用，具有强大的功能，能开出全部自动化单元及系统实验，DDC控制和SPC控制的实验。具有优良的性能价格比。