Bias-temperature instabilities (BTI) of HfO/sub 2/ metal oxide semiconductor field effect transistors (MOSFETs) have been systematically studied for the first time. NMOS positive BTI (PBTI) exhibited a more significant V/sub t/ instability than that of PMOS negative BTI (NBTI), and limited the lifetime of HfO/sub 2/ MOSFETs. Although high-temperature forming gas annealing (HT-FGA) improved the interface quality by passivating the interfacial states with hydrogen, BTI behaviors were not strongly affected by the technique. Charge pumping measurements were extensively used to investigate the nature of the BTI degradation, and it was found that V/sub t/ degradation of NMOS PBTI was primarily caused by charge trapping in bulk HfO/sub 2/ rather than interfacial degradation. Deuterium (D/sub 2/) annealing was found to be an excellent technique to improve BTI immunity as well as to enhance the mobility of HfO/sub 2/ MOSFETs. 相似文献
Considering the internet of things (IoT), end nodes such as wireless sensor network, RFID and embedded systems are used in many applications. These end nodes are known as resource-constrained devices in the IoT network. These devices have limitations such as computing and communication power, memory capacity and power. Key pre-distribution schemes (KPSs) have been introduced as a lightweight solution to key distribution in these devices. Key pre-distribution is a special type of key agreement that aims to select keys called session keys in order to establish secure communication between devices. One of these design types is the using of combinatorial designs in key pre-distribution, which is a deterministic scheme in key pre-distribution and has been considered in recent years. In this paper, by introducing a key pre-distribution scheme of this type, we stated that the model introduced in the two benchmarks of KPSs comparability had full connectivity and scalability among the designs introduced in recent years. Also, in recent years, among the combinatorial design-based key pre-distribution schemes, in order to increase resiliency as another criterion for comparing KPSs, attempts were made to include changes in combinatorial designs or they combine them with random key pre-distribution schemes and hybrid schemes were introduced that would significantly reduce the design connectivity. In this paper, using theoretical analysis and maintaining full connectivity, we showed that the strength of the proposed design was better than the similar designs while maintaining higher scalability.
Curcumin, the natural yellow‐colored active principle, also called turmeric yellow, extracted from the perennial herb Curcuma longa L., has potent biological and pharmacological properties such as antioxidant, anti‐inflammatory, antifungal, antibacterial, anti‐ischemic, antitumor, and anticancer actions. The molecular mechanism of the hepatoprotective action of curcumin is due to its antioxidant properties and inhibitory activity against nuclear factor (NF)‐κB that regulates different proinflammatory and profibrotic cytokines. Overall, scientific reports demonstrate that curcumin has high therapeutic ability for treating hepatic disorders. Here is a systematic discussion of the hepatoprotective activity of curcumin and its possible mechanisms of actions. 相似文献
Flavonoids play an important role in pharmaceutical and biomedical sciences. Various flavonoids, especially Morin, have potential to interact with DNA. Their prospective clinical and pharmacological utilities have attracted researchers?? attention in last two decades. Due to their interaction with DNA and their anticancer effects, a lot of investigations have been carried out all over the world. In this paper, we will review the properties of Morin and its different metal complexes as well as their interactions with DNA that have been reported by several research groups. Also, further details have been provided about binding mechanisms of these materials with DNA using analytical techniques such as UV?CVisible and fluorescence spectroscopies, viscosity and voltammetry. Structural analysis showed Morin binds to DNA through non-intercalation mode, but its metal complexes interact with DNA via intercalation mode and binding mode of Morin, and its metal complexes with DNA will be helpful in the determination of anticancer drugs binding mechanism to DNA. Therefore, it will be useful in new drug designs. 相似文献
The effect of copper(II) ions (Cu(+2)) on the structure of β-lactoglobulin (β-lg) was investigated spectroscopically using UV-visible, fluorescence and circular dichroism (CD) and calorimetrically using isothermal titration calorimetry (ITC), at different temperatures. Results of the UV-visible studies showed that adding Cu(+2) to β-lg solution caused increasing turbidity, indicative of protein aggregation. It was noticeable that the rate of increasing turbidity was directly proportional to increasing temperature. The far-UV CD studies displayed that the Cu(+2) cannot induce any significant changes in the secondary structures of β-lg at different temperatures. Also, the ITC data indicated that the binding process of Cu(+2) to β-lg is mainly entropically driven. The results highlight that copper ions cause the tertiary structure of β-lg to change and induce a slightly open structure leading to the formation of supramolecular aggregates in β-lg which may result in the reduced allergenicity of β-lg and its increased use in industrial applications. 相似文献
Since colossal ionic conductivity was detected in the planar heterostructures consisting of fluorite and perovskite,heterostructures have drawn great research interest as potential electrolytes for solid oxide fuel cells(SOFCs).However,so far,the practical uses of such promising material have failed to materialize in SOFCs due to the short circuit risk caused by SrTiO3.In this study,a series of fluorite/perovskite heterostructures made of Sm-doped CeO2 and SrTiO3(SDC–STO)are developed in a new bulk-heterostructure form and evaluated as electrolytes.The prepared cells exhibit a peak power density of 892 mW cm−2 along with open circuit voltage of 1.1 V at 550°C for the optimal composition of 4SDC–6STO.Further electrical studies reveal a high ionic conductivity of 0.05–0.14 S cm^−1 at 450–550°C,which shows remarkable enhancement compared to that of simplex SDC.Via AC impedance analysis,it has been shown that the small grain-boundary and electrode polarization resistances play the major roles in resulting in the superior performance.Furthermore,a Schottky junction effect is proposed by considering the work functions and electronic affinities to interpret the avoidance of short circuit in the SDC–STO cell.Our findings thus indicate a new insight to design electrolytes for low-temperature SOFCs. 相似文献
Most of the methods developed for efficiency estimation of distillation columns were based on the empirical mass transfer and hydraulic relations correlated to laboratory data. Therefore, these methods cannot estimate efficiency of industrial columns with sufficient accuracy. In this paper, a new and applicable method was developed for calculation of efficiency (and mass and heat transfer coefficients) of distillation columns containing structured packings. This method has potential advantages; e.g., it can calculate efficiency without using any empirical mass transfer and hydraulic correlations and models, and without the need to estimate the operational and hydraulic parameters of column. Therefore, it will be free of errors, limitations, and complexities of such empirical items. In addition, precision of the method does not decrease with increasing complexity of operating conditions and design parameters of column. The method can be used for efficiency calculation of any structured packing, including new ones, in distillation columns. 相似文献