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41.
Abstract

The main natural source of water available in Kuwait is the brackish groundwater located in the Kuwait Group and the Dammam aquifers, where the salinity ranges from 4300 to 10200 mg/l and from 2500 to 10000 mg/l, respectively. Limited fresh groundwater resources in Al‐Rawdhatain and Umm Al‐Aish fields, which have a salinity of 359 ‐1737 mg/l, are also available. Most of the groundwater in Kuwait is used for irrigation, domestic purposes, small‐scale industries and for blending with distilled water. Because rainfall is seasonal and less than annual evaporation, the recharge of the groundwater from rainfall is negligible. The objective of this paper is to assess the different water resources in Kuwait in order to make an integrated management plan and to focus on future sustainability. Generally, in the State of Kuwait, there is increasing pressure on the natural water resources because of the exploitation of the aquifers at a rate exceeding that of both the groundwater recharge and population growth (from 1.4 million in 1980 to 2.55 million in 2003). This has lead to the observed decline in groundwater level and to the deterioration of water quality. In the early 1950s, a plan was endorsed in Kuwait to establish seawater desalination plants. By 2005, six desalination plants have been established, with a total capacity of distillation units of 1434.72 ×103 m3/d (315.6 MIGD). However, the gross maximum consumption for the year 2003 reached a value of 1440.17 ×103 m3/d (316.8 MIGD), which is higher than the total capacity of the available distillation units. Given the limitation of conventional water and the shortages of non‐conventional water, along with the increasing population, Kuwait must consider the recycling of wastewater for irrigation, industrial or any other unrestricted non‐potable purpose.  相似文献   
42.
The multifocal electroretinography technique consists of performing sectorized light excitation of the retina and capturing the resulting evoked potential. This provides functional localized information about the state of the retinal neurons. Analysis of multifocal electroretinography signals can be used for diagnosing different types of optic neuropathies (glaucomatous, demyelinating and ischemic ethiology). In order to obtain a reliable diagnosis, it is necessary to apply advanced processing algorithms (morphological, frequency and time-frequency analysis, etc.) to the multifocal electroretinography signal. This paper presents a software application developed in MATLAB(?) (MathWorks Inc., MA) designed to perform advanced multifocal electroretinography signal analysis and classification. This intuitive application, mfERG_LAB, is used to plot the signals, apply various algorithms to them and present the data in an appropriate format. The application's computational power and modular structure make it suitable for use in clinical settings as a powerful and innovative diagnostic tool, as well as in research and teaching settings as a means of assessing new algorithms.  相似文献   
43.

Context

Several metrics have been proposed to measure the extent to which class members are related. Connectivity-based class cohesion metrics measure the degree of connectivity among the class members.

Objective

We propose a new class cohesion metric that has higher discriminative power than any of the existing cohesion metrics. In addition, we empirically compare the connectivity and non-connectivity-based cohesion metrics.

Method

The proposed class cohesion metric is based on counting the number of possible paths in a graph that represents the connectivity pattern of the class members. We theoretically and empirically validate this path connectivity class cohesion (PCCC) metric. The empirical validation compares seven connectivity-based metrics, including PCCC, and 11 non-connectivity-based metrics in terms of discriminative and fault detection powers. The discriminative-power study explores the probability that a cohesion metric will incorrectly determine classes to be cohesively equal when they have different connectivity patterns. The fault detection study investigates whether connectivity-based metrics, including PCCC, better explain the presence of faults from a statistical standpoint in comparison to other non-connectivity-based cohesion metrics, considered individually or in combination.

Results

The theoretical validation demonstrates that PCCC satisfies the key cohesion properties. The results of the empirical studies indicate that, in contrast to other connectivity-based cohesion metrics, PCCC is much better than any comparable cohesion metric in terms of its discriminative power. In addition, the results also indicate that PCCC measures cohesion aspects that are not captured by other metrics, wherein it is considerably better than other connectivity-based metrics but slightly worse than some other non-connectivity-based cohesion metrics in terms of its ability to predict faulty classes.

Conclusion

PCCC is more useful in practice for the applications in which practitioners need to distinguish between the quality of different classes or the quality of different implementations of the same class.  相似文献   
44.
45.
Valproic acid toxicity is not infrequent and is difficult to treat, as there is no specific antidote. In the past, this drug was considered unremovable by extracorporeal methods because of the highly protein bound state (90–95%). However, recent reports suggest that the toxicokinetics of valproate vary considerably from the pharmacokinetics at therapeutic levels, and at higher concentrations protein‐binding sites become saturated. The drug's relatively low molecular weight (144 Da), small volume of distribution (0.13–0.23 L/kg), and saturable protein binding render it potentially amenable to extracorporeal removal, but published experience is scant and there are only a few reported instances in which patients were successfully treated with extracorporeal methods. Here we report the case of a patient with serious valproate toxicity treated with simultaneous “in series” hemodialysis and hemoperfusion followed by continuous veno‐venous hemodiafiltration. A 35‐year‐old homeless male presented to the emergency department after ingesting 120 pills of valproic acid. Initial valproic acid level was 59 µg/mL. Urine drug screen was negative and serum chemistries including LFTs were normal. He was treated with activated charcoal and admitted to the intensive care unit. 4 h later, he developed respiratory failure and became hemodynamically unstable. He was intubated and successfully resuscitated. Subsequently, the valproic acid level was found to be 553 µg/mL and a decision was made to employ extracorporeal methods for drug removal. “In series” hemodialysis and hemoperfusion were done for 4 h and simultaneous blood samples for measurement of valproic acid levels were obtained as blood entered the hemoperfusion column (arterial) and as it exited the hemodialysis membrane (venous). Extraction ratio, whole blood, and plasma clearances were calculated and they compared substantially with the published data. The above measures decreased valproate levels from 572.6 (pre‐dialysis level) to 203.2 µg/mL. This was followed by continuous veno‐venous hemodiafiltration for 18 h, which sustained the drug removal and prevented significant post‐dialytic rebound. This is the first reported instance in which these three methods were administered together successfully in the management of valproic acid toxicity.  相似文献   
46.
47.
Waveguiding through a two-dimensional metallic photonic crystal   总被引:1,自引:0,他引:1  
We present a two‐dimensional (2D) finite‐difference time domain simulation of the propagation of light through linear and bent channels in metallic photonic crystals. We took as a starting point the Bozhevolnyi experiment, consisting of the scattering of surface plasmons by a 2D structure of finitely sized periodic gold dots arranged in a triangular lattice of 400‐nm period. We model injection and propagation of light through linear channels of different widths. We also study the behaviour of light in the presence of a 90° bent line defect made in the structure. We show that the confinement depends on the orientation of the input and output line defects. The two cases of ΓM and ΓK orientations are considered and a spectral study for five different wavelengths is carried out.  相似文献   
48.
Rosenbrock methods are known to be good in numerical modeling of stiff problems. In this work, a new symbolic algorithm is proposed for automating the derivation of order conditions for two-stage Rosenbrock schemes with complex coefficients. Software implementation of the proposed algorithm is discussed in detail.  相似文献   
49.
In this paper we propose an automatic methodology to verify the soundness of model checking reduction techniques. The idea is to use the consistency of the specifications to verify if the reduced model is faithful to the original one. The user provides the reduction technique, the specification and the system under verification. Then, using Higher Order Logic he verifies automatically if the reduction technique is soundly applied. The method is completely defined in an MDG–HOL special integration platform that combines an automatic high level model checking tool Multiway Decision Graphs (MDGs) within the HOL theorem prover. We provide two case studies, the first one is the reduction using SAT–MDG of an Island Tunnel Controller and the second one is the MDG–HOL assume-guarantee reduction of the Look-Aside Interface. The obtained results of our approach offer a considerable gain in terms of the correctness of heuristics and reduction techniques as applied to commercial model checking, however a small penalty is paid in terms of CPU time and memory usage.  相似文献   
50.
This paper analyzes the average bit error probability (BEP) of the differential binary and quaternary phase-shift keying (DBPSK and DQPSK respectively) with multiple-input multiple-output (MIMO) systems employing postdetection equal gain combining (MIMO EGC) diversity reception over Rayleigh fading channels. Finite closed-form expressions for the average BEP of DBPSK and DQPSK are presented. Two approaches are introduced to analyze the error rate of DQPSK. The proposed structure for the differential phase-shift keying (DPSK) with MIMO EGC provides a reduced-complexity and low-cost receiver for MIMO systems compared to the coherent phase-shift keying system (PSK) with MIMO employing maximal ratio combining (MIMO MRC) diversity reception. Finally, a useful procedure for computing the associated Legendre functions of the second kind with half-odd-integer order and arbitrarily degree is presented.  相似文献   
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