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181.
Sleep-related car crashes: risk perception and decision-making processes in young drivers 总被引:2,自引:0,他引:2
Lucidi F Russo PM Mallia L Devoto A Lauriola M Violani C 《Accident; analysis and prevention》2006,38(2):302-309
The aim of the present study is to analyse factors affecting worries, coping strategies and decisions of young drivers regarding the risk of sleep-related car crashes. Furthermore, the study also analyses whether framing the same information about sleepiness in two different linguistic forms influences: (1) the evaluation of the level of risk associated to a specific level of drowsiness (Attribute Framing problem); (2) the willingness to enact strategies to "prevent" sleepiness before night-time driving (Goal Framing problem); (3) the choice between two different ways, both of equal expected efficacy, of lowering drowsiness (Risky decision-making Framing problem). Six hundred and ninety-five young drivers [(57.6% females, 42.4% males); mean age 20.85 years (S.D.=1.2)] answered questions on drive risk perception and sleepiness, on nocturnal driving experience and on the strategies to deal with driver sleepiness, responding to one of the two different versions of the framed problems. A sub-sample of 130 participants completed the framed problems in both versions. The results show that experiences of sleep attacks and nocturnal driving frequency in the past 6 months affect both risk perception and the preventive strategies adopted. Furthermore, the manipulation on two out of the three problems (attribute and risky decision-making frames) significantly affected the respondents' evaluation. 相似文献
182.
A novel approach for carotenoid analysis has been developed. Orange essential oil and juice carotenoids were separated by means of comprehensive dual-gradient elution HPLC, using normal phase with a microbore silica column in the first dimension (first D), reversed phase with a monolithic C18 column in the second dimension (second D), and a 10-port switching valve as an interface. An on-line photodiode array detector was used in order to obtain absorption spectra. Peak identification was obtained by combining retention data with the UV-visible spectra. 相似文献
183.
The reversible addition-fragmentation chain-transfer polymerization was used to prepare microarray slides grafted with polymer brushes for DNA-based applications. Block copolymer brushes of N,N-dimethylacrylamide (DMA) and glycidyl methacrylate (GMA), poly(DMA-b-GMA) were prepared by extending living poly(dimethylacrylamide) chains. The functional surface was used as a substrate for oligonucleotide hybridization experiments. The results were compared to those provided by glass slides coated by a self-assembled monolayer made of (3-glycidyloxypropyl)trimethoxysilane. Surfaces coated with block polymer brushes bearing oxirane groups are more efficient as substrates for oligonucleotide hybridization than surfaces coated with nonpolymeric self-assembled monolayers containing the same functional group. The high probe grafting density and hybridization efficiency achieved with this polymeric coating reveal the importance of the block architecture to ensure good accessibility of the immobilized probe. The new surface was characterized by static angle measurements and diffuse reflectance FT-IR spectroscopy on a silica model system. 相似文献
184.
Immune protection of artificial tissue by means of pancreatic islet microencapsulation is a very ambitious new approach to avoid life-long immune suppression. But the success in the utilization of the alginate-beads with incorporated islets is unfortunately limited. Some of the problems cannot be solved by a two-component system, so polymer encapsulation of the microbeads was tested to improve the properties. In the present paper a pure nanoencapsulation multilayer approach was tested in order to reduce the size of the capsule and possibly apply in the future a multilayer capsule with individual properties in each layer or region of the capsule. Different polycations were attached in a self-assembly process. The advantage in using the surface charge of islets as binding site for the polyions is the guarantee of complete coverage after the second layer. Release of insulin was determined to characterize the function of the islets after encapsulation as well as the permeability of the capsule. Fluorescence microscopy was used to visualize the polyelectrolyte layers. Finally by means of an immune assay, the protection capability of the capsule was proved. In these first measurements the encapsulation with a multilayer nanocapsule was shown to be a possible alternative to the more space-consuming and random islet-trapping microencapsulation. 相似文献
185.
The purpose of this work is to evaluate the effect of a specific motorcycle licence, held by car drivers, in responsibility for motorcycle-car crashes. The data were provided by a multicentric case-control study (MAIDS) regarding the risk of crash and serious injuries of motorcyclists. A non-parametric method, classification and regression tree (CART), was used to accomplish the objective, and then compared to standard unconditional logistic regression. Drivers owning a motorcycle licence turned out to be less responsible for motorcycle-car crashes than drivers who do not have one; both types of analysis are consistent with this result. It is reasonable to assume that car drivers who hold a motorcycle licence have acquired more ability in riding and controlling two wheeled vehicles than drivers without a licence, and this may help them in predicting motorcycles manoeuvres. 相似文献
186.
187.
Tata A Fernandes AM Santos VG Alberici RM Araldi D Parada CA Braguini W Veronez L Silva Bisson G Reis FH Alberici LC Eberlin MN 《Analytical chemistry》2012,84(15):6341-6345
The ability of nanoassisted laser desorption-ionization mass spectrometry (NALDI-MS) imaging to provide selective chemical monitoring with proper spatial distribution of lipid profiles from tumor tissues after plate imprinting has been tested. NALDI-MS imaging identified and mapped several potential lipid biomarkers in a murine model of melanoma tumor (inoculation of B16/F10 cells). It also confirmed that the in vivo treatment of tumor bearing mice with synthetic supplement containing phosphoethanolamine (PHO-S) promoted an accentuated decrease in relative abundance of the tumor biomarkers. NALDI-MS imaging is a matrix-free LDI protocol based on the selective imprinting of lipids in the NALDI plate followed by the removal of the tissue. It therefore provides good quality and selective chemical images with preservation of spatial distribution and less interference from tissue material. The test case described herein illustrates the potential of chemically selective NALDI-MS imaging for biomarker discovery. 相似文献
188.
Cacciotti I Lombardi M Bianco A Ravaglioli A Montanaro L 《Journal of materials science. Materials in medicine》2012,23(8):1849-1866
In this work, the 45S5 bioactive glass was synthesized through an aqueous sol-gel method. Characteristic functional groups were evidenced by Fourier transform infrared spectroscopy, the thermal behaviour was investigated by thermogravimetric and differential thermal analysis, crystallization kinetics and phase evolution were followed by X-ray diffraction measurements. The sintering behaviour of the sol-gel derived 45S5 was then studied by dilatometry and the microstructural evolution was followed step-by-step, interrupting the thermal cycle at different temperatures. In vitro dissolution tests were performed in order to assess the degradation behaviour of sol-gel derived 45S5 samples thermally treated at different temperatures. A relevant influence of the calcination conditions (namely, dwelling time and temperature) of the as-prepared powder on the phase appearance and its sintering behaviour as well as on the porosity features, in terms of pore dimension and interconnectivity, of the fired materials was stated. 相似文献
189.
Accurate information on the actual performance of the structural system after retrofit is an essential part of a cost-effective bridge management program. This paper summarizes the results of a thorough experimental program concerning the reinforced concrete deck of a real 40 year-old viaduct. The structure exhibited severe damage at the extrados mainly due to environmental agents, chemical attack and action of asphalt milling machines. Samples of the deck were cut and carried to the laboratory in order to assess the possibility of retrofit. The design of retrofit was aimed at increasing the load carrying capacity through replacement of the deteriorated concrete with a new concrete overlay and strengthening in flexure for both negative (hogging) and positive (sagging) bending moments. Experimental testing on small specimens and nondestructive techniques were carried out to identify the material properties and to evaluate the level of damage. The bonding between external reinforcement and the original or new (standard or polymer-modified) concrete was assessed through single-shear push–pull tests on 33 prismatic specimens of 100 × 200 × 500 mm3 strengthened with CFRP strips. The efficiency of the retrofit techniques was checked at the structural level through four-point bending tests on eight slabs of 500 × 200 × 2000 mm3. This research can contribute to guidelines for concrete patch repair of FRP-retrofitted concrete bridge decks, to ensure better long-term performance under service loads and environmental effects. 相似文献
190.
Alessandra Olinda de Carvalho Lincoln Cardoso Brandão Túlio Hallak Panzera Carlos Henrique Lauro 《Journal of Materials Processing Technology》2012,212(8):1753-1760
Threads are used in the most assemblies of industrial products. Commonly, mechanical components need to have threaded parts allowing fast and accurate assemblies and disassemblies. Internal tapping is one of the most demanded machining operations, and threads obtained by forming have been a good alternative. This work investigates the effect of the factors the hole diameter, the forming speed and types of tool on the responses: torque, hardness, fill rate, and thrust force of the form tapping process. The experiments were carried out with three diameters, three forming speeds, and two coatings. The material used was the AM60 alloy due to its high ductility and wide application as head engine. The results revealed torque is more affected by the hole diameter than thrust force, and little hardening occurred using high forming speed with a small diameter. The fill rate of the thread profile was not significantly affected by the intermediate and large diameters. Finally, it can be stated that the recommended hole diameter provided by the tool's supplier can be modified to achieve more accurate thread profiles. 相似文献