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101.
Oxidative Stress Imaging: Visualizing Oxidative Cellular Stress Induced by Nanoparticles in the Subcytotoxic Range Using Fluorescence Lifetime Imaging (Small 23/2018) 下载免费PDF全文
102.
Y Furutani A Kato H Yasue LJ Alexander CW Beattie S Hirose 《Canadian Metallurgical Quarterly》1998,124(3):491-502
The purpose of the study was to examine the effects of manipulating lung volume (LV) on phonatory and articulatory kinematic behavior during sentence production in healthy adults. Five men and five women repeated the sentence "I sell a sapapple again" under five LV conditions. These included (1) speaking normally, (2) speaking after exhaling most of the air from the lungs, (3) speaking at end expiratory level (EEL), (4) speaking after a maximal inhalation, and (5) speaking after a maximal inhalation while attempting to maintain as normal a mode of speech as possible. From a multichannel recording, measures were made of LV, sound pressure level (SPL), fundamental frequency (F0) and semitone standard deviation (STSD), and upper and lower lip displacements and peak velocities. When compared with the reference condition, the sentence was spoken significantly more quickly at the lowest LV. SPL increased significantly for the high LV condition, as did the women's F0 and STSD. Upper lip displacements and peak velocities generally decreased for LVs other than the reference condition. Lower lip movements showed inconsistent changes as a function of LV. Adjustments to the LV for speech led to SPL and F0 changes consistent with a coordinated control of the respiratory system and the larynx. However, less consistent effects were observed in the articulatory kinematic measures, possibly because of a less direct biomechanical and neural control linkage between respiratory and articulatory structures. 相似文献
103.
Alexander Rabinovich 《Information and Computation》1996,124(2):154
We consider the problem of determining when two dataflow networks with uninterpreted nodes always have the same input-output behavior. We define a set of behavior-preserving transformations on networks and show that this set is “schematologically complete”; i.e., networks have the same input-output behavior under all interpretations if and only if they can be transformed into isomorphic networks. As a by product, we obtain a polynomial algorithm for deciding schematological equivalence of dataflow networks. 相似文献
104.
Georg Birkenheuer Andr�� Brinkmann Mikael H?gqvist Alexander Papaspyrou Bernhard Schott Dietmar Sommerfeld Wolfgang Ziegler 《Journal of Grid Computing》2011,9(3):355-377
Infrastructure federation is becoming an increasingly important issue for modern Distributed Computing Infrastructures (DCIs):
Dynamic elasticity of quasi-static Grid environments, incorporation of special-purpose resources into commoditized Cloud infrastructures,
cross-community collaboration for increasingly diverging areas of modern e-Science, and Cloud Bursting pose major challenges
on the technical level for many resource and middleware providers. Especially with respect to increasing costs of operating
data centers, the intelligent yet automated and secure sharing of resources is a key factor for success. With the D-Grid Scheduler
Interoperability (DGSI) project within the German D-Grid Initiative, we provide a strategic technology for the automatically
negotiated, SLA-secured, dynamically provisioned federation of resources and services for Grid-and Cloud-type infrastructures.
This goal is achieved by complementing current DCI schedulers with the ability to federate infrastructure for the temporary
leasing of resources and rechanneling of workloads. In this work, we describe the overall architecture and SLA-secured negotiation
protocols within DGSI and depict an advanced mechanism for resource delegation through means of dynamically provisioned, virtualized
middleware. Through this methodology, we provide the technological foundation for intelligent capacity planning and workload
management in a cross-infrastructure fashion. 相似文献
105.
106.
Classifiers based on radial basis function neural networks have a number of useful properties that can be exploited in many practical applications. Using sample data, it is possible to adjust their parameters (weights), to optimize their structure, and to select appropriate input features (attributes). Moreover, interpretable rules can be extracted from a trained classifier and input samples can be identified that cannot be classified with a sufficient degree of “certainty”. These properties support an analysis of radial basis function classifiers and allow for an adaption to “novel” kinds of input samples in a real-world application. In this article, we outline these properties and show how they can be exploited in the field of intrusion detection (detection of network-based misuse). Intrusion detection plays an increasingly important role in securing computer networks. In this case study, we first compare the classification abilities of radial basis function classifiers, multilayer perceptrons, the neuro-fuzzy system NEFCLASS, decision trees, classifying fuzzy-k-means, support vector machines, Bayesian networks, and nearest neighbor classifiers. Then, we investigate the interpretability and understandability of the best paradigms found in the previous step. We show how structure optimization and feature selection for radial basis function classifiers can be done by means of evolutionary algorithms and compare this approach to decision trees optimized using certain pruning techniques. Finally, we demonstrate that radial basis function classifiers are basically able to detect novel attack types. The many advantageous properties of radial basis function classifiers could certainly be exploited in other application fields in a similar way. 相似文献
107.
Bernhard Burgermeister Martin Arnold Alexander Eichberger 《Multibody System Dynamics》2011,26(1):1-14
The rapidly increasing complexity of multi-body system models in applications like vehicle dynamics, robotics and bio-mechanics
requires qualitative new solution methods to slash computing times for the dynamical simulation. 相似文献
108.
Zhengxiong Yang Stefan Kollmannsberger Alexander Düster Martin Ruess Eduardo Grande Garcia Rainer Burgkart Ernst Rank 《Computing and Visualization in Science》2011,14(5):207-216
Numerous numerical methods have been developed in an effort to accurately predict stresses in bones. The largest group are variants of the h-version of the finite element method (h-FEM), where low order Ansatz functions are used. By contrast, we3 investigate a combination of high order FEM and a fictitious domain approach, the finite cell method (FCM). While the FCM has been verified and validated in previous publications, this article proposes methods on how the FCM can be made computationally efficient to the extent that it can be used for patient specific, interactive bone simulations. This approach is called computational steering and allows to change input parameters like the position of an implant, material or loads and leads to an almost instantaneous change in the output (stress lines, deformations). This direct feedback gives the user an immediate impression of the impact of his actions to an extent which, otherwise, is hard to obtain by the use of classical non interactive computations. Specifically, we investigate an application to pre-surgical planning of a total hip replacement where it is desirable to select an optimal implant for a specific patient. Herein, optimal is meant in the sense that the expected post-operative stress distribution in the bone closely resembles that before the operation. 相似文献
109.
Oleksandr?PanchenkoEmail author Hasso?Plattner Alexander?B.?Zeier 《Information Systems Frontiers》2011,13(3):349-357
Enabling fast and detailed insights over large portions of source code is an important task in a global development ecosystem.
Numerous data structures have been developed to store source code and to support various structural queries, to help in navigation,
evaluation and analysis. Many of these data structures work with tree-based or graph-based representations of source code.
The goal of this project is to elaborate a data storage that enables efficient storing and fast querying of structural information.
The naive adjacency list method has been enhanced with the use of recent data compression approaches for column-oriented databases
to allow no-loss albeit compact storage of fine-grained structural data. The graph indexing has enabled the proposed data
model to expeditiously answer fine-grained structural queries. This paper describes the basics of the proposed approach and
illustrates its technical feasibility. 相似文献
110.
We present and analyze an unsupervised method for Word Sense Disambiguation (WSD). Our work is based on the method presented
by McCarthy et al. in 2004 for finding the predominant sense of each word in the entire corpus. Their maximization algorithm allows weighted
terms (similar words) from a distributional thesaurus to accumulate a score for each ambiguous word sense, i.e., the sense
with the highest score is chosen based on votes from a weighted list of terms related to the ambiguous word. This list is
obtained using the distributional similarity method proposed by Lin Dekang to obtain a thesaurus. In the method of McCarthy
et al., every occurrence of the ambiguous word uses the same thesaurus, regardless of the context where the ambiguous word occurs.
Our method accounts for the context of a word when determining the sense of an ambiguous word by building the list of distributed
similar words based on the syntactic context of the ambiguous word. We obtain a top precision of 77.54% of accuracy versus
67.10% of the original method tested on SemCor. We also analyze the effect of the number of weighted terms in the tasks of
finding the Most Frecuent Sense (MFS) and WSD, and experiment with several corpora for building the Word Space Model. 相似文献