Observing Proteins as Single Molecules Encapsulated in Surface‐Tethered Polymeric Nanocontainers

Protein unfolding inside immobilized polymerosomes : One of the most interesting properties of polymeric vesicles is their remarkable stability against extreme temperatures and osmotic stress, and their longevity even under harsh environmental conditions. We have demonstrated, in an application on protein folding, that surface‐tethered polymerosomes are suitable for performing time‐resolved single molecule studies with encapsulated proteins, as illustrated here.

     

Go Brown: Inner-Disciplinary Conjectures

The relationship of society to its excrement is telling at both a cultural and social level. The notion of green architecture with its emphasis on the naturally pure has so far eschewed waste as a primary generative material. Alexandros Tsamis here invokes a more inclusive notion of the environment in which by-product becomes intrinsic to any project. Copyright © 2010 John Wiley & Sons, Ltd.     

Simulation-based robust design of mass dampers for response mitigation of tension leg platforms

A robust stochastic design framework is discussed for design of mass dampers. The focus is on applications for the mitigation of the coupled heave and pitch response of Tension Leg Platforms under stochastic sea excitation. The framework presented fully addresses the complex relationship between the coupled dynamics of the platform, the stochastic excitation and the vibration of the dampers. Model parameters that have some level of uncertainty are probabilistically described. In this probabilistic setting, the system reliability is adopted as the design objective. Stochastic simulation is considered for evaluation of the system model response and the overall reliability performance. This way, all nonlinear characteristics of the structural response and environmental excitation are explicitly incorporated into their respective models. An efficient algorithm is discussed for performing the challenging stochastic design optimization. The ideas are illustrated in an application involving a tension leg platform with closely spaced frequencies for the heave and pitch degrees of freedom.     

Symmetric wedge in the roof of a tunnel excavated in an inclined stress field

An analytical method is presented for the calculation of the stability of a two-dimensional symmetric rock wedge which is formed in the roof of an underground circular opening within an inclined biaxial stress field. The stability of the wedge is evaluated using a two-stage relaxation procedure. In the first stage, the forces acting on the joint faces of the wedge are calculated analytically from the elastic stress distribution around the opening. Thus, formulae are provided that calculate the horizontal and vertical force components on the wedge faces exerted by the surrounding rock mass. In the second stage, a steadily increasing pull out force is applied to the wedge which strains its joints. Failure is assumed to occur due to simultaneous yield along the face of one of the joints. The stability of the wedge, which is expressed by its pull out resistance, is calculated from limit equilibrium equations at failure. Finally, analytically calculated values of the pull out resistance of the wedge are compared with numerically obtained ones using a discrete element code.     

Biomimetic Omnidirectional Antireflective Glass via Direct Ultrafast Laser Nanostructuring

Here, a single‐step, biomimetic approach for the realization of omnidirectional transparent antireflective glass is reported. In particular, it is shown that circularly polarized ultrashort laser pulses produce self‐organized nanopillar structures on fused silica (SiO₂). The laser‐induced nanostructures are selectively textured on the glass surface in order to mimic the spatial randomness, pillar‐like morphology, as well as the remarkable antireflection properties found on the wings of the glasswing butterfly, Greta oto, and various Cicada species. The artificial structures exhibit impressive antireflective properties, both in the visible and infrared frequency ranges, which are remarkably stable over time. Accordingly, the laser‐processed glass surfaces show reflectivity smaller than 1% for various angles of incidence in the visible spectrum for s–p linearly polarized configurations. However, in the near‐infrared spectrum, the laser‐textured glass shows higher transmittance compared to the pristine. It is envisaged that the current results will revolutionize the technology of antireflective transparent surfaces and impact numerous applications from glass displays to optoelectronic devices.