A new case of the unstable haemoglobin Genova (alpha 2 beta 2 28 (beta 10) leu leads to pro) in Canada: as a result of sporadic mutation and causing Heinz body haemolytic anaemia

The first case of the unstable Hb Genova as a result of sporadic mutation is described. It is found in a 3-year-old Canadian boy of East Indian extraction with chronic Heinz body haemolytic anaemia.     

Surface-active agents in the aqueous phase of the hot-water flotation process for oil sands

Sulphoxides were identified in the aqueous phase of the Hot-Water Flotation Process (HWFP) for the separation of oil from tar sand. The ease of formation of these polar compounds is demonstrated. Sulphonic acids and carboxylic acids were also detected in the aqueous phase and a tentative mechanism for their formation from organic sulphides via sulphoxides is suggested. The relevance of our results to the chemistry of oil spills is discussed.     

Effect of the addition of Ca2+ on the structure, microstructure and ferroelectric properties of (Pb1 − y Ca y )(Zr0.8Ti0.2)O3 system with y = 0.0, 0.02, 0.05 and 0.1

This work studies the relationship between ferroelectric properties and structural features of the (Pb_{1 – y} Ca _y )(Zr_0.8Ti_0.2)O₃ system with y = 0.0, 0.02, 0.05 and 0.1. All of the samples were prepared by hot-pressing of PZT calcined powder, prepared by conventional ceramic route. Single phase compositions of rhombohedral (RH) structure were observed for the whole series of the samples studied in this work. However, a linear decrease of RH lattice constant a _p is seen with increasing the Ca²⁺ concentration with a subsequent decrease of lattice strain expressed by (90 – _p). Further, a sharp decline is also observed in the magnitudes of saturation polarization (P _s) of the samples doped with 2 mol% Ca²⁺. However, the rate of decrease slows down for Ca²⁺ concentrations above this level. A diffuse phase transition was observed in the case of 10 mol% Ca²⁺-doped PZT(0.8) which is believed to be possibly due to the distribution in coupling strengths created from a random compositional fluctuations of Ca²⁺ and Pb^2– ions on A-sites. The results are interpreted on crystal-chemical grounds. It is proposed that the long range coupling of (Zr/Ti)O₆ coordination octahedra and Pb²⁺ ions, due to the covalency of the Pb–O bond, is interrupted by the incorporation of Ca²⁺. By considering the effect of calcium on coupling strength and coupling distribution, the observed dielectric response for the above compositions is qualitatively explained.     

Analysis of traffic accidents at urban intersections in Riyadh

Previous studies have shown that intersection-related accidents account for about 50% of all accidents registered annually in Riyadh, the capital of the Kingdom of Saudi Arabia (KSA). More than half of these accidents are classified as severe. In this study, an attempt was made to investigate traffic accidents that occurred at both intersections and non-intersection sites. The goal was to analyze the nature of such accidents to determine their characteristics so that remedies could be sought or at least future research could be suggested. For this purpose, a sample of 1774 reported accidents was collected in a systematic random manner for the period 1996-1998 (651 severe accidents (accidents resulting in at least one personal injury or fatality) and 1123 property-damage-only (PDO) accidents). Conditional probability and contingency table analyses were used to make inferences from the data. The study found that improper driving behavior is the primary cause of accidents at signalized urban intersections in Riyadh; running a red light and failing to yield are the primary contributing causes. The analysis indicates that there is an urgent need to review existing intersection geometry along with the traffic control devices installed at these sites. In addition, public education campaigns and law enforcement strategies are urgently needed.     

Objective-type dark-field illumination for scattering from microbeads

We introduce a method for detecting and tracking small particles in a solution near a surface. The method is based on blocking the backreflected illumination beam in an objective-type total internal reflection microscope, leaving unhindered the light scattered by the particles and resulting in dark-field illumination. Using this method, we tracked the motion of 60-nm polystyrene beads with a signal-to-noise ratio of 6 and detected 20-nm gold particles with a signal-to-noise ratio of 5. We illustrate the method's use by following the Brownian motion of small beads attached by short DNA tethers to a substrate.     

Sepiolite-PAN intercalation used as Si3N4 forming precursor

Silicon nitride (Si₃N₄) formation was investigated using sepiolite and polyacrylonitrile as silicon and carbon source, respectively. It was found that purified sepiolite could readily adsorb a sufficient amount of acrylonitrile (AN) reagent without pre-treatment. Polymerisation of sepiolite-AN mixtures and subsequent cyclization of the polymerised complex yielded a precursor, which was found ideal as a starting material in carbothermal reduction-nitridation (CRN) for the formation of silicon nitride powders. The quantity of silicon nitride, grain size and morphology were found to be dependent on the reaction conditions and starting reagent. Fine grain size, high surface area (up to approx. 12.4 m²/g) powders of mainly -Si₃N₄ were obtained via pyrolysis of sepiolite-PAN complex after 4 h heating at 1400°C in 1000 ml/min nitrogen flow with a heating rate of 300°C/h. Mg retained in the molecular structure of the mineral must have promoted the formation of -grains in CRN process.     

Allozyme polymorphism and variability in permethrin tolerance in British populations of the parthenogenetic stored product pest Liposcelis bostrychophila (Liposcelididae, Psocoptera)

Variability in allozyme patterns is demonstrated among 111 British populations of Liposcelis bostrychophila (Badonnel), an obligatory parthenogenetic liposcelid species that is a common domestic pest in the United Kingdom. In addition four tropical strains and a laboratory culture were included in the analysis. Permethrin toxicity was measured in a subset of the populations.Using cellulose acetate paper electrophoresis, 16 of 34 enzymes tested were found in the liposcelid material and, of these, four were polymorphic. A total of 47 distinct morphs were recognised. This enzyme variation appears to be random with respect to geography throughout the country.Permethrin tolerance was highly variable among populations. A significant relationship was demonstrated between the mean LC(50) for permethrin and latitude such that there appears to be higher levels of tolerance in southern, than in northern, Britain.No link could be established between the allozyme polymorphisms, particularly in the esterases, and permethrin tolerance.     

A hybrid multi-objective shuffled frog-leaping algorithm for a mixed-model assembly line sequencing problem

In this paper, a mixed-model assembly line (MMAL) sequencing problem is studied. This type of production system is used to manufacture multiple products along a single assembly line while maintaining the least possible inventories. With the growth in customers’ demand diversification, mixed-model assembly lines have gained increasing importance in the field of management. Among the available criteria used to judge a sequence in MMAL, the following three are taken into account: the minimization of total utility work, total production rate variation, and total setup cost. Due to the complexity of the problem, it is very difficult to obtain optimum solution for this kind of problems by means of traditional approaches. Therefore, a hybrid multi-objective algorithm based on shuffled frog-leaping algorithm (SFLA) and bacteria optimization (BO) are deployed. The performance of the proposed hybrid algorithm is then compared with three well-known genetic algorithms, i.e. PS-NC GA, NSGA-II, and SPEA-II. The computational results show that the proposed hybrid algorithm outperforms the existing genetic algorithms, significantly in large-sized problems.     

Header Detection to Improve Multimedia Quality Over Wireless Networks

Wireless multimedia studies have revealed that forward error correction (FEC) on corrupted packets yields better bandwidth utilization and lower delay than retransmissions. To facilitate FEC-based recovery, corrupted packets should not be dropped so that maximum number of packets is relayed to a wireless receiver's FEC decoder. Previous studies proposed to mitigate wireless packet drops by a partial checksum that ignored payload errors. Such schemes require modifications to both transmitters and receivers, and incur packet-losses due to header errors. In this paper, we introduce a receiver-based scheme which uses the history of active multimedia sessions to detect transmitted values of corrupted packet headers, thereby improving wireless multimedia throughput. Header detection is posed as the decision-theoretic problem of multihypothesis detection of known parameters in noise. Performance of the proposed scheme is evaluated using trace-driven video simulations on an 802.11b local area network. We show that header detection with application layer FEC provides significant throughput and video quality improvements over the conventional UDP/IP/802.11 protocol stack