Complete nucleotide sequence of the Plasmodium vivax 6 kb element

A small survey confirms that epidural infusions are often prepared by clinicians and solutions may be changed each day because of fears of microbiological contamination. We have assessed the microbiological safety of six mixtures of diamorphine (0.01-1.0%) and bupivacaine (0.1-0.5%) representing the spectrum of clinically useful concentrations for use as extradural infusions. The solutions were studied for antibacterial activity against common contaminants of fluids: Escherichia coli, Pseudomonas aeruginosa, Enterococcus faecalis and a coagulase negative Staphylococcus sp. A saline control was included. Challenge experiments used an inoculum of approximately 5.0 x 10(6) cfu/ml. Mixtures were incubated at 30 degrees C for up to 7 days. Viable counts of all organisms decreased with time for all the formulations tested. Formulations containing 0.5% bupivacaine were rapidly bactericidal, and increasing diamorphine concentrations increased this effect. Formulations with 0.5% bupivacaine had more activity than those with 0.1% bupivacaine. Mixtures of diamorphine and bupivacaine in concentrations used clinically have bactericidal activity against commonly encountered skin organisms. The common practice of changing every day epidural infusions containing these drugs is unnecessary.     

Non-linear elastic thermal stress analysis with phase changes

The non-linear elastic, thermal stress analysis with temperature induced phase changes in the materials is presented. An infinite plate (or body) with a circular hole (or tunnel) is subjected to a thermal loading on its inner surface. The peak temperature around the hole reaches beyond the melting point of the material. The non-linear diffusion equation is solved numerically using the finite difference method. The material properties change rapidly at temperatures where the change of crystal structures and solid-liquid transition occur. The elastic stresses induced by the transient non-homogeneous temperature distribution are calculated. The stresses change remarkably when the phase changes occur and there are residual stresses remaining in the plate after one cycle of thermal loading.     

Improvement of multicrystalline silicon solar cells by a low temperature anneal after emitter diffusion

The influence of an annealing step at about 500 °C after emitter diffusion of multicrystalline solar cells is investigated. Neighboring wafers from a silicon ingot were processed using different annealing durations and temperatures. The efficiency of the cells was measured and detailed light beam induced current measurements were performed. These show that mainly areas with high contents of precipitates near the crucible walls are affected by the anneal. An efficiency increase from 14.5 to 15.4% by a 2 h anneal at 500 °C was observed. The effect seems to be more likely external than internal gettering. Copyright © 2010 John Wiley & Sons, Ltd.     

Wheat gluten: high molecular weight glutenin subunits--structure, genetics, and relation to dough elasticity

ABSTRACT:  Gluten proteins, representing the major protein fraction of the starchy endosperm, are predominantly responsible for the unique position of wheat amongst cereals. These form a continuous proteinaceous matrix in the cells of the mature dry grain and form a continuous viscoelastic network during the mixing process of dough development. These viscoelastic properties underline the utilization of wheat to prepare bread and other wheat flour based foodstuffs. One group of gluten proteins is glutenin, which consists of high molecular weight (HMW) and low molecular weight (LMW) subunits. The HMW glutenin subunits (HMW-GS) are particularly important for determining dough elasticity. The common wheat possesses 3 to 5 HMW subunits encoded at the Glu-1 loci on the long arms of group 1 chromosomes (1A, 1B, and 1D). The presence of certain HMW subunits is positively correlated with good bread-making quality. Glutamine-rich repetitive sequences that comprise the central part of the HMW subunits are actually responsible for the elastic properties due to extensive arrays of interchain hydrogen bonds. Genetic engineering can be used to manipulate the amount and composition of the HMW subunits, leading to either increased dough strength or more drastic changes in gluten structure and properties.     

DOE applied to multi-response optimisation study on performance,combustion and emission characteristics of a VCR diesel engine

There are various parameters which may influence the IC engine performance. The trial and error method is a technique used to identify the best parameters. However, this method demands extensive experimental work and results in a great waste of time and resources. Thus, the design of experiments (DOEs) developed by Taguchi is employed. The multi-responses which need to be maximised are brake thermal efficiency, mechanical efficiency, cylinder pressure and cumulative heat release rate, whereas the responses which are to be minimised are specific fuel consumption, oxides of nitrogen and carbon monoxide. In the present study, an optimised DOE(L9) orthogonal array based on the Taguchi statistical method was formulated and a series of experiments were conducted under controlled supervision by considering three different injection operating pressures (IOPs) (200, 220 and 240 bar) and three different compression ratios (CRs) (16.5, 17.5 and 18.5). The main objective of this paper is to find the best suited IOP and CR values which obtain higher performance, better combustion and lower emissions.     

Photochemical reactions of polyene sequences produced during the degradation of poly(vinyl chloride)

Photosensitized reactions of tetrahydrofuran (THF) and dichloromethane (DCM) solutions of polyene sequences introduced into poly(vinyl chloride) molecules by chemical degradation have been investigated. The distribution of polyenes produced following further thermal degradation in DCM were shifted toward longer sequences than were observed for the same reaction in THF. Benzophenone-sensitized bleaching of the polyene absorption in aerated THF solutions was characterized by induction periods, but the presence of oxygen had little effect on the same reaction in DCM. The bleaching process seems to involve reaction of the polyenes with the tetrahydrofuranyl radical formed by abstraction of the α-hydrogen from THF by triplet benzophenone. No induction periods were observed for benzoin-sensitized reactions, but the rate of reaction was faster in DCM than in THF. The differences are discussed in terms of the difference in reactivity of the alkyl and alkoxy radicals.     

Influence of subchronic exposure to lindane on humoral immunity in mice

Lindane suppressed both primary and secondary antibody responses to sheep red blood cell (SRBC) in albino mice, the effects being more pronounced on the secondary than the primary response. However, a longer duration of pesticide exposure induced similar degrees of immunosuppression on both responses. The sequential study of plaque forming cells (PFC) kinetics revealed that suppression of plaque formation not only occurred at peak days but also on pre and post peak days, and there was no delay in peak antibody formation. Moreover, reduction in the primary PFC was not associated with decrease in the antibody response to SRBC. The results indicate that lindane suppresses both primary and secondary humoral immune responses in a time and dose dependent manner, and suggest a threshold susceptibility to exposure.