排序方式: 共有66条查询结果,搜索用时 15 毫秒
51.
Evgeniy N. Gribov Anastasiya Yu. Zinovieva Ivan N. Voropaev Pavel A. Simonov Anatoliy V. Romanenko Aleksey G. Okunev 《International Journal of Hydrogen Energy》2012
In this paper, a systematic investigation was carried out of activities at 80 °C of Pt supported on Sibunit-1562 graphitized carbon in the electroreduction of oxygen in the polymer electrolyte fuel cell. Pt content in the Pt/Sibunit-1562 catalysts was 20, 40, and 60 wt.% and Pt load at the cathode was varied in the 200–6.25 μgPt cm−2 interval. The results were compared with the activity of commercial 20 wt.% Pt/Vulcan XC-72 catalyst. To optimize the transport properties of the cathode layer and maintain its thickness upon using Pt/Sibunit −1562 catalysts with varied Pt content and Pt loads a definite amount of Vulcan-XC-72 carbon support was added to the cathode catalytic inks. Higher activity of Pt/Sibunit-1562 catalysts was found as compared to that of commercial 20 wt.% Pt/Vulcan XC-72 with similar particle size of the active component. 相似文献
52.
Mariya B. Borgoyakova Larisa I. Karpenko Andrey P. Rudometov Ekaterina A. Volosnikova Iuliia A. Merkuleva Ekaterina V. Starostina Alexey M. Zadorozhny Anastasiya A. Isaeva Valentina S. Nesmeyanova Daniil V. Shanshin Konstantin O. Baranov Natalya V. Volkova Boris N. Zaitsev Lyubov A. Orlova Anna V. Zaykovskaya Oleg V. Pyankov Elena D. Danilenko Sergei I. Bazhan Dmitry N. Shcherbakov Alexander V. Taranin Alexander A. Ilyichev 《International journal of molecular sciences》2022,23(4)
Despite the fact that a range of vaccines against COVID-19 have already been created and are used for mass vaccination, the development of effective, safe, technological, and affordable vaccines continues. We have designed a vaccine that combines the recombinant protein and DNA vaccine approaches in a self-assembled particle. The receptor-binding domain (RBD) of the spike protein of SARS-CoV-2 was conjugated to polyglucin:spermidine and mixed with DNA vaccine (pVAXrbd), which led to the formation of particles of combined coronavirus vaccine (CCV-RBD) that contain the DNA vaccine inside and RBD protein on the surface. CCV-RBD particles were characterized with gel filtration, electron microscopy, and biolayer interferometry. To investigate the immunogenicity of the combined vaccine and its components, mice were immunized with the DNA vaccine pVAXrbd or RBD protein as well as CCV-RBD particles. The highest antigen-specific IgG and neutralizing activity were induced by CCV-RBD, and the level of antibodies induced by DNA or RBD alone was significantly lower. The cellular immune response was detected only in the case of DNA or CCV-RBD vaccination. These results demonstrate that a combination of DNA vaccine and RBD protein in one construct synergistically increases the humoral response to RBD protein in mice. 相似文献
53.
Anastasiya Sedova Gregory Leitus Yishay Feldman Tatyana Bendikov Ronit Popovitz-Biro Sergey Khodorov Hanna Dodiuk Shmuel Kenig Reshef Tenne 《Journal of Materials Science》2017,52(11):6376-6387
Owing to their unique properties such as mechanical, optical, magnetic, nanomaterials attracted a great interest over the last two decades. Inorganic nanotubes, e.g. WS2, make an important class of nanomaterials with numerous potential applications. In the current work, a new synthetic strategy is developed to decorate the surface of WS2 nanotubes with FeWO4 nanoparticles. The FeWO4 nanoparticles were produced by first depositing amorphous iron oxide film onto the WS2 nanotubes’ surface and, subsequently, high-temperature annealing (600 °C). Careful analysis by electron microscopy; X-ray diffraction and other techniques were carried out. Based on these analyses, the growth mechanism of the hybrid nanostructures was elucidated. Magnetic measurements were employed to shed light on the magnetic behavior of the hybrid nanostructures. The orientation and position of the WS2 nanotubes decorated with the FeWO4 nanoparticles could be partially affected by applying a magnetic field using non-viscous solvents, like ethanol. 相似文献
54.
Ancuta Nartea Anastasiya Kuhalskaya Benedetta Fanesi Oghenetega Lois Orhotohwo Karolina Susek Lorenzo Rocchetti Valerio Di Vittori Elena Bitocchi Deborah Pacetti Roberto Papa 《Comprehensive Reviews in Food Science and Food Safety》2023,22(3):1953-1985
The demand for high-quality alternative food proteins has increased over the last few decades due to nutritional and environmental concerns, leading to the growing consumption of legumes such as common bean, chickpea, lentil, lupin, and pea. However, this has also increased the quantity of non-utilized byproducts (such as seed coats, pods, broken seeds, and wastewaters) that could be exploited as sources of ingredients and bioactive compounds in a circular economy. This review focuses on the incorporation of legume byproducts into foods when they are formulated as flours, protein/fiber or solid/liquid fractions, or biological extracts and uses an analytical approach to identify their nutritional, health-promoting, and techno-functional properties. Correlation-based network analysis of nutritional, technological, and sensory characteristics was used to explore the potential of legume byproducts in food products in a systematic manner. Flour is the most widely used legume-based food ingredient and is present at levels of 2%–30% in bakery products, but purified fractions and extracts should be investigated in more detail. Health beverages and vegan dressings with an extended shelf-life are promising applications thanks to the techno-functional features of legume byproducts (e.g., foaming and emulsifying behaviors) and the presence of polyphenols. A deeper exploration of eco-friendly processing techniques (e.g., fermentation and ohmic treatment) is necessary to improve the techno-functional properties of ingredients and the sensory characteristics of foods in a sustainable manner. The processing of legume byproducts combined with improved legume genetic resources could enhance the nutritional, functional, and technological properties of ingredients to ensure that legume-based foods achieve wider industrial and consumer acceptance. 相似文献
55.
Pavel V. Maslennikov Galina N. Chupakhina Liubov N. Skrypnik Pavel V. Feduraev Anastasiya S. Melnik 《The International journal of environmental studies》2018,75(5):719-731
This article considers the concentration of lead, polyphenols and water-soluble antioxidants (AOA) in the leaves of 4 species of woody, 11 species of shrub and 7 species of herbaceous plants growing in different functional zones in the city of Kaliningrad. The accumulations of Pb – the principal pollutant in urban ecosystems – were studied in the urban topsoil and plant leaves. An increase in Pb concentration in soils was associated with a decrease in AOA in tissues of the species examined. Changes in the background concentrations of antioxidants make it possible to estimate plant resistance to environmental stresses. The authors examine the contribution of polyphenols to the antioxidant potential of urban plants in soil polluted by Pb. The results obtained can be used to determine urban plant resistance to human impact and to improve the monitoring of industrial pollution in urban areas. 相似文献
56.
Anastasiya Gorodilova Sergey Agievich Claude Carlet Xiang-dong Hou Valeria Idrisova Nikolay Kolomeec 《Cryptologia》2020,44(3):223-256
AbstractProblems and their solutions of the Fifth International Students’ Olympiad in cryptography NSUCRYPTO’2018 are presented. We consider problems related to attacks on ciphers and hash functions, Boolean functions, quantum circuits, Enigma, etc. We discuss several open problems on orthogonal arrays, Sylvester matrices, and disjunct matrices. The problem of existing an invertible Sylvester matrix whose inverse is again a Sylvester matrix was completely solved during the Olympiad. 相似文献
57.
Vladimir A. Kuimov Svetlana F. Malysheva Nina K. Gusarova Anastasiya O. Korocheva 《Journal of Sulfur Chemistry》2014,35(2):137-144
Aromatic alkenes (vinylbenzene, 1-(tert-butyl)-4-vinylbenzene, 1-chloro-4-vinylbenzene) react with red phosphorus and elemental sulfur in the superbasic system KOH–DMSO(H2O) under microwave irradiation (600 W, 6–8 min, Ar) in the presence of hydroquinone to afford tris(2-phenylethyl)-, tris[2-(4-tBu-phenyl)ethyl]- and tris[2-(4-Cl-phenyl)ethyl]phosphine sulfides in 53%, 38% and 42% yield, respectively. 相似文献
58.
Anastasiya A. Kasimova Nikolay P. Arbatsky Jacob Tickner Johanna J. Kenyon Ruth M. Hall Michael M. Shneider Alina A. Dzhaparova Alexander S. Shashkov Alexander O. Chizhov Anastasiya V. Popova Yuriy A. Knirel 《International journal of molecular sciences》2021,22(11)
Whole genome sequences of two Acinetobacter baumannii clinical isolates, 48-1789 and MAR24, revealed that they carry the KL106 and KL112 capsular polysaccharide (CPS) biosynthesis gene clusters, respectively, at the chromosomal K locus. The KL106 and KL112 gene clusters are related to the previously described KL11 and KL83 gene clusters, sharing genes for the synthesis of l-rhamnose (l-Rhap) and 6-deoxy-l-talose (l-6dTalp). CPS material isolated from 48-1789 and MAR24 was studied by sugar analysis and Smith degradation along with one- and two-dimensional 1H and 13C NMR spectroscopy. The structures of K106 and K112 oligosaccharide repeats (K units) l-6dTalp-(1→3)-D-GlcpNAc tetrasaccharide fragment share the responsible genes in the respective gene clusters. The K106 and K83 CPSs also have the same linkage between K units. The KL112 cluster includes an additional glycosyltransferase gene, Gtr183, and the K112 unit includes α l-Rhap side chain that is not found in the K106 structure. K112 further differs in the linkage between K units formed by the Wzy polymerase, and a different wzy gene is found in KL112. However, though both KL106 and KL112 share the atr8 acetyltransferase gene with KL83, only K83 is acetylated. 相似文献
59.
Oxana Kazakova Codrua oica Marat Babaev Anastasiya Petrova Elmira Khusnutdinova Alexander Poptsov Ioana Macaoi George Drghici tefana Avram Lavinia Vlaia Alexandra Mioc Marius Mioc Cristina Dehelean Adrian Voicu 《International journal of molecular sciences》2021,22(19)
Cancer persists as a global challenge due to the extent to which conventional anticancer therapies pose high risks counterbalanced with their therapeutic benefit. Naturally occurring substances stand as an important safer alternative source for anticancer drug development. In the current study, a series of modified lupane and ursane derivatives was subjected to in vitro screening on the NCI-60 cancer cell line panel. Compounds 6 and 7 have been identified as highly active with GI50 values ranging from 0.03 µM to 5.9 µM (compound 6) and 0.18–1.53 µM (compound 7). Thus, these two compounds were further assessed in detail in order to identify a possible antiproliferative mechanism of action. DAPI (4′,6-diamidino-2-phenylindole) staining revealed that both compounds induced nuclei condensation and overall cell morphological changes consistent with apoptotic cell death. rtPCR analysis showed that both compounds induced upregulation of proapoptotic Bak and Bad genes while downregulating Bcl-XL and Bcl-2 antiapoptotic genes. Molecular docking analysis revealed that both compounds exhibited high scores for Bcl-XL inhibition, while compound 7 showed higher in silico Bcl-XL inhibition potential as compared to the native inhibitor ATB-737, suggesting that compounds may induce apoptotic cell death through targeted antiapoptotic protein inhibition, as well. 相似文献
60.
Yurii I. Evdokimenko Vyacheslav M. Kisel' Valerii Kh. Kadyrov Anastasiya A. Korol' Irina A. Podchernyaeva Alla D. Panasyuk 《Powder Metallurgy and Metal Ceramics》2003,42(11-12):578-586
We examine a new method for high-velocity gas-flame spraying: spraying of powdered materials by two-chamber torch devices, implementing the concept of flow rate control of the parameters of the carrier gas stream in their gasdynamic circuits. We give the parameters for the two-phase stream in the circuit of a two-chamber torch, obtained as a result of numerical modeling of the thermodynamic and gasdynamic processes in it. We show that maximum thermal efficiency for such torches is achieved when the flow rate of the gas phase through the front combustion chamber makes up 10 to 50% of the total flow rate. In this case, the enthalpy of the particles achieved during heating in two-chamber torches is 1.5 to 2 times greater than the enthalpy in torches of conventional design. The results of a comprehensive structural analysis of the coatings deposited by the new type of torches are evidence that they are of good quality and have high-level service properties. We demonstrate the prospects for using a composite powder based on Al2O3 – SiC for spraying low-porosity wear and corrosion resistant coatings that are functional at elevated temperatures. 相似文献